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Procedure price report · Pathology

Computer-assisted probe stain measurement, multiple probes

CPT 88374the billing code this page is about

Quantitative or semiquantitative measurement of an in situ hybridization stain that uses a combined multi-probe (multiplex) stain, read with computer-assisted technology; billed per stain procedure.

Hospitals typically charge $359 cash for this outpatient procedure — the median across 1,856 hospitals that filed a usable cash price; the average of the middle 60% is $376. Most fall between $187 and $647 (20th–80th percentile).

Hospitals
1,856
States
49
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,856 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$114$209$359$591$960

The most expensive tenth of hospitals charges at least 8.5× what the cheapest tenth charges ($114 vs $960).

How the prices are spread

$67 – $91: 52 hospitals$67$91 – $123: 66 hospitals$123 – $167: 92 hospitals$123$167 – $226: 240 hospitals$226 – $307: 251 hospitals$226$307 – $416: 284 hospitals$416 – $565: 274 hospitals$416$565 – $766: 231 hospitals$766 – $1,040: 95 hospitals$766$1,040 – $1,411: 87 hospitals$1,040median $359price bands are equal on a log scale
Hospitals per price band (1,672 of 1,856 — the bands cover the 5th to 95th percentile)
FromToHospitals
$67$9152
$91$12366
$123$16792
$167$226240
$226$307251
$307$416284
$416$565274
$565$766231
$766$1,04095
$1,040$1,41187

Against Medicare

Medicare pays (OPPS 2026, national rate)$174
Median cash price$359
Cash as a multiple of Medicare2.1×

The Medicare figure is the national unadjusted OPPS rate for this code — what Medicare itself pays a hospital before local wage adjustment. It is a benchmark, not a price anyone is charged.

By state

The median cash price in each state, against the national median of $359.

Alaska: 7 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 4 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 1 hospital filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $799 across 10 hospitalsNH$799Washington: median $378 across 56 hospitalsWA$378Idaho: median $323 across 15 hospitalsID$323Montana: 8 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $179 across 20 hospitalsMN$179Illinois: median $461 across 77 hospitalsIL$461Wisconsin: median $248 across 38 hospitalsWI$248Michigan: median $226 across 45 hospitalsMI$226New York: median $318 across 62 hospitalsNY$318Massachusetts: median $489 across 30 hospitalsMA$489Oregon: median $432 across 31 hospitalsOR$432Nevada: 9 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 8 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 6 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $326 across 42 hospitalsIA$326Indiana: median $212 across 76 hospitalsIN$212Ohio: median $465 across 84 hospitalsOH$465Pennsylvania: median $323 across 99 hospitalsPA$323New Jersey: median $221 across 41 hospitalsNJ$221Connecticut: median $382 across 11 hospitalsCT$382Rhode Island: median $285 across 10 hospitalsRI$285California: median $260 across 79 hospitalsCA$260Utah: median $1,411 across 34 hospitalsUT$1,411Colorado: median $510 across 40 hospitalsCO$510Nebraska: median $458 across 33 hospitalsNE$458Missouri: median $367 across 43 hospitalsMO$367Kentucky: median $358 across 36 hospitalsKY$358West Virginia: median $411 across 14 hospitalsWV$411Virginia: median $420 across 59 hospitalsVA$420Maryland: median $268 across 27 hospitalsMD$268Delaware: 4 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $413 across 27 hospitalsAZ$413New Mexico: 9 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $488 across 34 hospitalsKS$488Arkansas: median $211 across 17 hospitalsAR$211Tennessee: median $228 across 67 hospitalsTN$228North Carolina: median $288 across 67 hospitalsNC$288South Carolina: median $482 across 40 hospitalsSC$482Oklahoma: median $270 across 40 hospitalsOK$270Louisiana: median $222 across 27 hospitalsLA$222Mississippi: median $128 across 20 hospitalsMS$128Alabama: median $542 across 31 hospitalsAL$542Georgia: median $383 across 60 hospitalsGA$383Hawaii: median $727 across 15 hospitalsHI$727Texas: median $362 across 152 hospitalsTX$362Florida: median $269 across 91 hospitalsFL$269
Cash price by state, most expensive first. National median $359. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT34$1,411+293%$373 – $1,660
New Hampshire NH10$799+123%$577 – $1,420
Hawaii HI15$727+103%$121 – $854
Alabama AL31$542+51%$112 – $1,077
Colorado CO40$510+42%$341 – $603
Massachusetts MA30$489+36%$317 – $734
Kansas KS34$488+36%$260 – $908
South Carolina SC40$482+34%$297 – $536
Ohio OH84$465+30%$300 – $945
Illinois IL77$461+28%$159 – $685
Nebraska NE33$458+28%$276 – $746
Oregon OR31$432+20%$204 – $785
Virginia VA59$420+17%$114 – $568
Arizona AZ27$413+15%$209 – $1,282
West Virginia WV14$411+14%$250 – $595
Georgia GA60$383+7%$292 – $438
Connecticut CT11$382+7%$314 – $434
Washington WA56$378+5%$256 – $502
Missouri MO43$367+2%$205 – $566
Texas TX152$362+1%$232 – $640
Kentucky KY36$3580%$223 – $686
Iowa IA42$326−9%$292 – $563
Idaho ID15$323−10%$308 – $879
Pennsylvania PA99$323−10%$174 – $660
New York NY62$318−11%$203 – $614
North Carolina NC67$288−20%$184 – $647
Rhode Island RI10$285−21%$190 – $304
Oklahoma OK40$270−25%$69 – $363
Florida FL91$269−25%$140 – $631
Maryland MD27$268−25%$193 – $468
California CA79$260−28%$56 – $605
Wisconsin WI38$248−31%$216 – $625
Tennessee TN67$228−36%$114 – $577
Michigan MI45$226−37%$151 – $428
Louisiana LA27$222−38%$144 – $399
New Jersey NJ41$221−38%$187 – $551
Indiana IN76$212−41%$148 – $399
Arkansas AR17$211−41%$187 – $675
Minnesota MN20$179−50%$135 – $767
Mississippi MS20$128−64%$77 – $188
New Mexico NM9not enough hospitals filed a usable price
Nevada NV9not enough hospitals filed a usable price
Montana MT8not enough hospitals filed a usable price
Wyoming WY8not enough hospitals filed a usable price
Alaska AK7not enough hospitals filed a usable price
South Dakota SD6not enough hospitals filed a usable price
Delaware DE4not enough hospitals filed a usable price
Maine ME4not enough hospitals filed a usable price
Vermont VT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $359.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,513$353$179 – $625
Children’s18fewer than 20 hospitals
Critical access316$372$217 – $752
Ownership
For-profit293$399$184 – $801
Government265$377$188 – $647
Non-profit1,289$347$188 – $625
System affiliation
Part of a system1,589$359$187 – $650
Independent267$359$190 – $600

Cash price vs list price

Median list price (chargemaster)$631
Median cash price$359
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,318 hospitals filed a usable inpatient cash price for this code. The median is $362 and the average of the middle 60% is $380; most fall between $192 and $625.

Cash price percentiles, inpatient, across 1,318 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$114$216$362$574$886

The most expensive tenth of hospitals charges at least 7.8× what the cheapest tenth charges ($114 vs $886).

Of the 1,472 hospitals that filed this code inpatient, 1,318 gave a usable cash price; 96 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 58 a list price only.

How complete is this

1,856 of the 3,956 hospitals with a price file in our corpus (47%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 2,037 hospitals that filed this code at all gave us
Usable cash price — counted1,856
Cash price carrying a plausibility flag — shown on the compare tool, excluded here116
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded63
Hospitals that filed this code2,037

Sections not shown for this setting

  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as Microscopic genetic analysis of tissue, computer-assisted technology, initial procedure, each multiplex procedure.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Computer-assisted probe stain measurement, multiple probes (CPT 88374) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-88374-computer-assisted-probe-stain-measurement-multiple-probes