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Procedure price report · Pathology

Special tissue stain for one more marker

CPT 88341the billing code this page is about

Immunohistochemistry staining of a tissue sample to look for one additional marker beyond the first; billed once for each extra antibody stain on the same specimen.

Hospitals typically charge $145 cash for this outpatient procedure — the median across 3,113 hospitals that filed a usable cash price; the average of the middle 60% is $147. Most fall between $63 and $262 (20th–80th percentile).

Hospitals
3,113
States
50
Filings dated
Mar 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 3,113 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$43$74$145$229$374

The most expensive tenth of hospitals charges at least 8.7× what the cheapest tenth charges ($43 vs $374).

How the prices are spread

$28 – $38: 101 hospitals$28$38 – $50: 181 hospitals$50 – $67: 246 hospitals$50$67 – $90: 281 hospitals$90 – $120: 323 hospitals$90$120 – $160: 444 hospitals$160 – $214: 519 hospitals$160$214 – $286: 366 hospitals$286 – $382: 212 hospitals$286$382 – $510: 136 hospitals$382median $145price bands are equal on a log scale
Hospitals per price band (2,809 of 3,113 — the bands cover the 5th to 95th percentile)
FromToHospitals
$28$38101
$38$50181
$50$67246
$67$90281
$90$120323
$120$160444
$160$214519
$214$286366
$286$382212
$382$510136

By state

The median cash price in each state, against the national median of $145.

Alaska: median $196 across 12 hospitalsAK$196Maine: median $99 across 28 hospitalsME$99Vermont: median $166 across 12 hospitalsVT$166New Hampshire: median $209 across 25 hospitalsNH$209Washington: median $124 across 70 hospitalsWA$124Idaho: median $108 across 22 hospitalsID$108Montana: median $197 across 23 hospitalsMT$197North Dakota: median $193 across 32 hospitalsND$193Minnesota: median $143 across 108 hospitalsMN$143Illinois: median $192 across 135 hospitalsIL$192Wisconsin: median $150 across 106 hospitalsWI$150Michigan: median $90 across 98 hospitalsMI$90New York: median $158 across 105 hospitalsNY$158Massachusetts: median $152 across 50 hospitalsMA$152Oregon: median $136 across 47 hospitalsOR$136Nevada: median $94 across 13 hospitalsNV$94Wyoming: median $150 across 13 hospitalsWY$150South Dakota: median $200 across 35 hospitalsSD$200Iowa: median $169 across 85 hospitalsIA$169Indiana: median $152 across 96 hospitalsIN$152Ohio: median $161 across 140 hospitalsOH$161Pennsylvania: median $141 across 111 hospitalsPA$141New Jersey: median $119 across 42 hospitalsNJ$119Connecticut: median $161 across 21 hospitalsCT$161Rhode Island: 9 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $170 across 151 hospitalsCA$170Utah: median $186 across 40 hospitalsUT$186Colorado: median $204 across 65 hospitalsCO$204Nebraska: median $190 across 78 hospitalsNE$190Missouri: median $143 across 71 hospitalsMO$143Kentucky: median $160 across 63 hospitalsKY$160West Virginia: median $64 across 36 hospitalsWV$64Virginia: median $145 across 69 hospitalsVA$145Maryland: median $145 across 40 hospitalsMD$145Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $105 across 34 hospitalsAZ$105New Mexico: median $94 across 24 hospitalsNM$94Kansas: median $222 across 76 hospitalsKS$222Arkansas: median $87 across 37 hospitalsAR$87Tennessee: median $79 across 76 hospitalsTN$79North Carolina: median $151 across 87 hospitalsNC$151South Carolina: median $183 across 48 hospitalsSC$183Oklahoma: median $114 across 59 hospitalsOK$114Louisiana: median $58 across 49 hospitalsLA$58Mississippi: median $57 across 52 hospitalsMS$57Alabama: median $128 across 35 hospitalsAL$128Georgia: median $137 across 96 hospitalsGA$137Hawaii: median $234 across 19 hospitalsHI$234Texas: median $141 across 217 hospitalsTX$141Florida: median $74 across 146 hospitalsFL$74
Cash price by state, most expensive first. National median $145. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Hawaii HI19$234+62%$188 – $284
Kansas KS76$222+54%$94 – $374
New Hampshire NH25$209+45%$39 – $394
Colorado CO65$204+41%$137 – $348
South Dakota SD35$200+38%$106 – $297
Montana MT23$197+36%$97 – $263
Alaska AK12$196+35%$83 – $441
North Dakota ND32$193+33%$129 – $238
Illinois IL135$192+33%$119 – $345
Nebraska NE78$190+31%$93 – $344
Utah UT40$186+28%$144 – $219
South Carolina SC48$183+27%$108 – $278
California CA151$170+17%$37 – $192
Iowa IA85$169+17%$96 – $292
Vermont VT12$166+15%$136 – $329
Connecticut CT21$161+11%$90 – $249
Ohio OH140$161+11%$75 – $266
Kentucky KY63$160+11%$85 – $279
New York NY105$158+9%$54 – $265
Indiana IN96$152+5%$93 – $264
Massachusetts MA50$152+5%$95 – $232
North Carolina NC87$151+5%$57 – $273
Wyoming WY13$150+4%$95 – $199
Wisconsin WI106$150+4%$93 – $239
Maryland MD40$1450%$97 – $192
Virginia VA69$1450%$104 – $261
Minnesota MN108$143−1%$78 – $211
Missouri MO71$143−1%$94 – $185
Texas TX217$141−3%$74 – $325
Pennsylvania PA111$141−3%$47 – $272
Georgia GA96$137−5%$71 – $179
Oregon OR47$136−6%$66 – $185
Alabama AL35$128−12%$65 – $405
Washington WA70$124−14%$74 – $188
New Jersey NJ42$119−18%$79 – $437
Oklahoma OK59$114−21%$45 – $205
Idaho ID22$108−25%$60 – $169
Arizona AZ34$105−27%$71 – $374
Maine ME28$99−32%$59 – $264
Nevada NV13$94−35%$32 – $333
New Mexico NM24$94−35%$56 – $262
Michigan MI98$90−38%$44 – $158
Arkansas AR37$87−40%$55 – $183
Tennessee TN76$79−45%$44 – $149
Florida FL146$74−49%$34 – $365
West Virginia WV36$64−56%$44 – $151
Louisiana LA49$58−60%$25 – $131
Mississippi MS52$57−60%$26 – $102
Rhode Island RI9not enough hospitals filed a usable price
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $145.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,229$141$59 – $264
Children’s59$159$85 – $257
Critical access815$158$75 – $248
Ownership
For-profit440$155$66 – $392
Government520$140$60 – $255
Non-profit2,143$145$62 – $243
System affiliation
Part of a system2,573$148$65 – $262
Independent540$130$57 – $252

Cash price vs list price

Median list price (chargemaster)$235
Median cash price$145
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

2,170 hospitals filed a usable inpatient cash price for this code. The median is $146 and the average of the middle 60% is $148; most fall between $64 and $257.

Cash price percentiles, inpatient, across 2,170 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$45$75$146$228$349

The most expensive tenth of hospitals charges at least 7.8× what the cheapest tenth charges ($45 vs $349).

Of the 2,397 hospitals that filed this code inpatient, 2,170 gave a usable cash price; 123 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 104 a list price only.

How complete is this

3,113 of the 3,956 hospitals with a price file in our corpus (79%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,428 hospitals that filed this code at all gave us
Usable cash price — counted3,113
Cash price carrying a plausibility flag — shown on the compare tool, excluded here137
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded2
A list price only, no cash figure — excluded176
Hospitals that filed this code3,428

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as Imhchem/Imcytchm Ea Addl Single Antb Stain Px|TECHNICAL COMPONENT.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Special tissue stain for one more marker (CPT 88341) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-88341-special-tissue-stain-for-one-more-marker