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Procedure price report · Pathology

Factor V Leiden blood clotting gene mutation test

CPT 81241the billing code this page is about

Laboratory test of the F5 gene for the single Factor V Leiden variant associated with an increased tendency to form blood clots. Covers one test on one sample.

Hospitals typically charge $193 cash for this outpatient procedure — the median across 3,174 hospitals that filed a usable cash price; the average of the middle 60% is $203. Most fall between $84 and $367 (20th–80th percentile).

Hospitals
3,174
States
50
Filings dated
Dec 2022 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 3,174 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$53$96$193$331$513

The most expensive tenth of hospitals charges at least 9.8× what the cheapest tenth charges ($53 vs $513).

How the prices are spread

$37 – $50: 145 hospitals$37$50 – $68: 151 hospitals$68 – $91: 289 hospitals$68$91 – $123: 289 hospitals$123 – $166: 352 hospitals$123$166 – $223: 405 hospitals$223 – $300: 420 hospitals$223$300 – $403: 417 hospitals$403 – $543: 258 hospitals$403$543 – $731: 132 hospitals$543median $193price bands are equal on a log scale
Hospitals per price band (2,858 of 3,174 — the bands cover the 5th to 95th percentile)
FromToHospitals
$37$50145
$50$68151
$68$91289
$91$123289
$123$166352
$166$223405
$223$300420
$300$403417
$403$543258
$543$731132

By state

The median cash price in each state, against the national median of $193.

Alaska: median $203 across 17 hospitalsAK$203Maine: median $123 across 28 hospitalsME$123Vermont: median $254 across 14 hospitalsVT$254New Hampshire: median $251 across 24 hospitalsNH$251Washington: median $230 across 74 hospitalsWA$230Idaho: median $112 across 22 hospitalsID$112Montana: median $261 across 29 hospitalsMT$261North Dakota: median $247 across 31 hospitalsND$247Minnesota: median $187 across 103 hospitalsMN$187Illinois: median $270 across 134 hospitalsIL$270Wisconsin: median $256 across 102 hospitalsWI$256Michigan: median $101 across 85 hospitalsMI$101New York: median $165 across 105 hospitalsNY$165Massachusetts: median $245 across 48 hospitalsMA$245Oregon: median $223 across 47 hospitalsOR$223Nevada: median $221 across 20 hospitalsNV$221Wyoming: median $218 across 15 hospitalsWY$218South Dakota: median $278 across 33 hospitalsSD$278Iowa: median $205 across 87 hospitalsIA$205Indiana: median $147 across 94 hospitalsIN$147Ohio: median $189 across 137 hospitalsOH$189Pennsylvania: median $289 across 117 hospitalsPA$289New Jersey: median $84 across 56 hospitalsNJ$84Connecticut: median $220 across 21 hospitalsCT$220Rhode Island: median $142 across 10 hospitalsRI$142California: median $123 across 137 hospitalsCA$123Utah: median $407 across 42 hospitalsUT$407Colorado: median $177 across 65 hospitalsCO$177Nebraska: median $314 across 75 hospitalsNE$314Missouri: median $220 across 72 hospitalsMO$220Kentucky: median $162 across 66 hospitalsKY$162West Virginia: median $226 across 42 hospitalsWV$226Virginia: median $176 across 73 hospitalsVA$176Maryland: median $122 across 39 hospitalsMD$122Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $248 across 37 hospitalsAZ$248New Mexico: median $280 across 25 hospitalsNM$280Kansas: median $221 across 81 hospitalsKS$221Arkansas: median $88 across 39 hospitalsAR$88Tennessee: median $107 across 81 hospitalsTN$107North Carolina: median $139 across 88 hospitalsNC$139South Carolina: median $450 across 47 hospitalsSC$450Oklahoma: median $197 across 69 hospitalsOK$197Louisiana: median $110 across 47 hospitalsLA$110Mississippi: median $105 across 51 hospitalsMS$105Alabama: median $203 across 41 hospitalsAL$203Georgia: median $231 across 102 hospitalsGA$231Hawaii: median $187 across 17 hospitalsHI$187Texas: median $276 across 232 hospitalsTX$276Florida: median $52 across 146 hospitalsFL$52
Cash price by state, most expensive first. National median $193. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Carolina SC47$450+134%$153 – $464
Utah UT42$407+112%$293 – $479
Nebraska NE75$314+63%$163 – $423
Pennsylvania PA117$289+50%$85 – $902
New Mexico NM25$280+45%$112 – $562
South Dakota SD33$278+44%$188 – $418
Texas TX232$276+43%$117 – $692
Illinois IL134$270+40%$122 – $518
Montana MT29$261+36%$123 – $362
Wisconsin WI102$256+33%$156 – $421
Vermont VT14$254+32%$178 – $505
New Hampshire NH24$251+30%$137 – $440
Arizona AZ37$248+29%$83 – $355
North Dakota ND31$247+28%$128 – $500
Massachusetts MA48$245+27%$204 – $400
Georgia GA102$231+20%$109 – $422
Washington WA74$230+19%$155 – $310
West Virginia WV42$226+17%$115 – $392
Oregon OR47$223+16%$110 – $352
Nevada NV20$221+15%$54 – $308
Kansas KS81$221+15%$104 – $321
Connecticut CT21$220+14%$119 – $312
Missouri MO72$220+14%$154 – $322
Wyoming WY15$218+13%$130 – $268
Iowa IA87$205+7%$128 – $380
Alaska AK17$203+5%$115 – $458
Alabama AL41$203+5%$88 – $402
Oklahoma OK69$197+2%$100 – $315
Ohio OH137$189−2%$98 – $350
Hawaii HI17$187−3%$157 – $370
Minnesota MN103$187−3%$100 – $352
Colorado CO65$177−8%$92 – $329
Virginia VA73$176−9%$105 – $592
New York NY105$165−14%$73 – $339
Kentucky KY66$162−16%$91 – $293
Indiana IN94$147−24%$76 – $364
Rhode Island RI10$142−26%$116 – $352
North Carolina NC88$139−28%$76 – $229
California CA137$123−36%$40 – $281
Maine ME28$123−36%$59 – $205
Maryland MD39$122−37%$57 – $176
Idaho ID22$112−42%$60 – $233
Louisiana LA47$110−43%$57 – $211
Tennessee TN81$107−44%$50 – $249
Mississippi MS51$105−45%$60 – $272
Michigan MI85$101−47%$50 – $349
Arkansas AR39$88−54%$48 – $283
New Jersey NJ56$84−56%$73 – $207
Florida FL146$52−73%$32 – $189
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $193.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,216$176$74 – $352
Children’s49$175$95 – $357
Critical access899$233$111 – $397
Ownership
For-profit432$201$60 – $470
Government586$200$88 – $347
Non-profit2,146$192$84 – $361
System affiliation
Part of a system2,595$192$81 – $385
Independent579$193$93 – $342

Cash price vs list price

Median list price (chargemaster)$312
Median cash price$193
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

2,150 hospitals filed a usable inpatient cash price for this code. The median is $201 and the average of the middle 60% is $211; most fall between $87 and $380.

Cash price percentiles, inpatient, across 2,150 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$57$105$201$340$527

The most expensive tenth of hospitals charges at least 9.2× what the cheapest tenth charges ($57 vs $527).

Of the 2,371 hospitals that filed this code inpatient, 2,150 gave a usable cash price; 113 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 108 a list price only.

How complete is this

3,174 of the 3,956 hospitals with a price file in our corpus (80%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,460 hospitals that filed this code at all gave us
Usable cash price — counted3,174
Cash price carrying a plausibility flag — shown on the compare tool, excluded here155
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded129
Hospitals that filed this code3,460

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between July 20, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Factor V Leiden Mutation.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Factor V Leiden blood clotting gene mutation test (CPT 81241) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81241-factor-v-leiden-blood-clotting-gene-mutation-test