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Procedure price report · Pathology

Manual probe count on tissue, each added probe

CPT 88369the billing code this page is about

In situ hybridization with hand counting of gene or chromosome signals; billed once for each additional single probe stain beyond the first on the same specimen.

Hospitals typically charge $217 cash for this outpatient procedure — the median across 1,073 hospitals that filed a usable cash price; the average of the middle 60% is $225. Most fall between $101 and $386 (20th–80th percentile).

Hospitals
1,073
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,073 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$60$122$217$334$521

The most expensive tenth of hospitals charges at least 8.7× what the cheapest tenth charges ($60 vs $521).

How the prices are spread

$41 – $54: 39 hospitals$41$54 – $72: 49 hospitals$72 – $96: 65 hospitals$72$96 – $127: 76 hospitals$127 – $170: 156 hospitals$127$170 – $226: 123 hospitals$226 – $301: 163 hospitals$226$301 – $401: 164 hospitals$401 – $533: 82 hospitals$401$533 – $710: 51 hospitals$533median $217price bands are equal on a log scale
Hospitals per price band (968 of 1,073 — the bands cover the 5th to 95th percentile)
FromToHospitals
$41$5439
$54$7249
$72$9665
$96$12776
$127$170156
$170$226123
$226$301163
$301$401164
$401$53382
$533$71051

By state

The median cash price in each state, against the national median of $217.

Alaska: 2 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 9 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 4 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $246 across 13 hospitalsWA$246Idaho: 4 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 4 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureNDMinnesota: median $229 across 22 hospitalsMN$229Illinois: median $386 across 52 hospitalsIL$386Wisconsin: median $311 across 55 hospitalsWI$311Michigan: median $161 across 40 hospitalsMI$161New York: median $144 across 33 hospitalsNY$144Massachusetts: median $143 across 16 hospitalsMA$143Oregon: median $256 across 20 hospitalsOR$256Nevada: 8 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureSDIowa: median $292 across 21 hospitalsIA$292Indiana: median $159 across 36 hospitalsIN$159Ohio: median $237 across 52 hospitalsOH$237Pennsylvania: median $152 across 43 hospitalsPA$152New Jersey: 8 hospitals filed a usable price — fewer than 10, so no figureNJConnecticut: 6 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 4 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $283 across 47 hospitalsCA$283Utah: median $267 across 11 hospitalsUT$267Colorado: median $156 across 19 hospitalsCO$156Nebraska: median $435 across 19 hospitalsNE$435Missouri: median $234 across 29 hospitalsMO$234Kentucky: median $242 across 20 hospitalsKY$242West Virginia: median $36 across 10 hospitalsWV$36Virginia: median $217 across 29 hospitalsVA$217Maryland: median $200 across 21 hospitalsMD$200Delaware: no hospital in the corpus filed a usable priceDEArizona: median $233 across 22 hospitalsAZ$233New Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $239 across 21 hospitalsKS$239Arkansas: median $234 across 16 hospitalsAR$234Tennessee: median $48 across 34 hospitalsTN$48North Carolina: median $205 across 38 hospitalsNC$205South Carolina: median $79 across 10 hospitalsSC$79Oklahoma: median $234 across 27 hospitalsOK$234Louisiana: median $181 across 12 hospitalsLA$181Mississippi: median $126 across 18 hospitalsMS$126Alabama: median $94 across 18 hospitalsAL$94Georgia: median $199 across 51 hospitalsGA$199Hawaii: 7 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $196 across 72 hospitalsTX$196Florida: median $306 across 56 hospitalsFL$306
Cash price by state, most expensive first. National median $217. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Nebraska NE19$435+101%$122 – $547
Illinois IL52$386+78%$179 – $465
Wisconsin WI55$311+43%$279 – $529
Florida FL56$306+41%$136 – $456
Iowa IA21$292+35%$173 – $292
California CA47$283+30%$130 – $325
Utah UT11$267+23%$170 – $360
Oregon OR20$256+18%$184 – $377
Washington WA13$246+13%$69 – $390
Kentucky KY20$242+12%$106 – $253
Kansas KS21$239+10%$93 – $342
Ohio OH52$237+9%$137 – $710
Arkansas AR16$234+8%$69 – $346
Missouri MO29$234+8%$167 – $332
Oklahoma OK27$234+8%$55 – $382
Arizona AZ22$233+8%$93 – $445
Minnesota MN22$229+6%$168 – $265
Virginia VA29$2170%$72 – $290
North Carolina NC38$205−6%$177 – $386
Maryland MD21$200−8%$145 – $244
Georgia GA51$199−8%$159 – $610
Texas TX72$196−10%$101 – $332
Louisiana LA12$181−17%$64 – $315
Michigan MI40$161−26%$45 – $311
Indiana IN36$159−27%$134 – $239
Colorado CO19$156−28%$137 – $284
Pennsylvania PA43$152−30%$25 – $591
New York NY33$144−34%$63 – $334
Massachusetts MA16$143−34%$90 – $178
Mississippi MS18$126−42%$105 – $198
Alabama AL18$94−57%$55 – $270
South Carolina SC10$79−63%$45 – $426
Tennessee TN34$48−78%$33 – $85
West Virginia WV10$36−84%$34 – $78
Maine ME9not enough hospitals filed a usable price
New Jersey NJ8not enough hospitals filed a usable price
Nevada NV8not enough hospitals filed a usable price
Hawaii HI7not enough hospitals filed a usable price
Connecticut CT6not enough hospitals filed a usable price
Idaho ID4not enough hospitals filed a usable price
Montana MT4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
Rhode Island RI4not enough hospitals filed a usable price
Vermont VT4not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price
Alaska AK2not enough hospitals filed a usable price
North Dakota ND1not enough hospitals filed a usable price
South Dakota SD1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $217.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care882$207$99 – $386
Children’s7fewer than 20 hospitals
Critical access177$233$103 – $367
Ownership
For-profit140$218$107 – $418
Government145$179$81 – $357
Non-profit781$221$101 – $384
System affiliation
Part of a system953$221$101 – $386
Independent120$160$81 – $357

Cash price vs list price

Median list price (chargemaster)$371
Median cash price$217
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

789 hospitals filed a usable inpatient cash price for this code. The median is $220 and the average of the middle 60% is $230; most fall between $101 and $396.

Cash price percentiles, inpatient, across 789 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$68$120$220$368$557

The most expensive tenth of hospitals charges at least 8.2× what the cheapest tenth charges ($68 vs $557).

Of the 901 hospitals that filed this code inpatient, 789 gave a usable cash price; 65 carried a plausibility flag, 1 filed a number their own filing marks as not a price, 0 gave an estimate, and 46 a list price only.

How complete is this

1,073 of the 3,956 hospitals with a price file in our corpus (27%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,212 hospitals that filed this code at all gave us
Usable cash price — counted1,073
Cash price carrying a plausibility flag — shown on the compare tool, excluded here62
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded3
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded74
Hospitals that filed this code1,212

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as M/Phmtrc Alys Ish Quant/Semiq Mnl per Spec Each|PROFESSIONAL COMPONENT.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Manual probe count on tissue, each added probe (CPT 88369) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-88369-manual-probe-count-on-tissue-each-added-probe