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Procedure price report · Pathology

Probe test on tissue for one more target

CPT 88364the billing code this page is about

In situ hybridization, in which a labeled probe binds a specific genetic sequence in tissue; billed once for each additional single probe beyond the first.

Hospitals typically charge $210 cash for this outpatient procedure — the median across 2,286 hospitals that filed a usable cash price; the average of the middle 60% is $217. Most fall between $103 and $378 (20th–80th percentile).

Hospitals
2,286
States
50
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 2,286 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$69$117$210$335$524

The most expensive tenth of hospitals charges at least 7.6× what the cheapest tenth charges ($69 vs $524).

How the prices are spread

$46 – $61: 74 hospitals$46$61 – $80: 122 hospitals$80 – $106: 175 hospitals$80$106 – $139: 241 hospitals$139 – $184: 276 hospitals$139$184 – $242: 334 hospitals$242 – $318: 313 hospitals$242$318 – $419: 256 hospitals$419 – $551: 174 hospitals$419$551 – $726: 93 hospitals$551median $210price bands are equal on a log scale
Hospitals per price band (2,058 of 2,286 — the bands cover the 5th to 95th percentile)
FromToHospitals
$46$6174
$61$80122
$80$106175
$106$139241
$139$184276
$184$242334
$242$318313
$318$419256
$419$551174
$551$72693

By state

The median cash price in each state, against the national median of $210.

Alaska: 7 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $124 across 27 hospitalsME$124Vermont: 7 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $323 across 12 hospitalsNH$323Washington: median $158 across 45 hospitalsWA$158Idaho: median $175 across 19 hospitalsID$175Montana: median $239 across 11 hospitalsMT$239North Dakota: median $206 across 12 hospitalsND$206Minnesota: median $254 across 73 hospitalsMN$254Illinois: median $328 across 96 hospitalsIL$328Wisconsin: median $258 across 83 hospitalsWI$258Michigan: median $151 across 66 hospitalsMI$151New York: median $209 across 67 hospitalsNY$209Massachusetts: median $217 across 41 hospitalsMA$217Oregon: median $252 across 37 hospitalsOR$252Nevada: 9 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 6 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 8 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $279 across 46 hospitalsIA$279Indiana: median $164 across 74 hospitalsIN$164Ohio: median $196 across 117 hospitalsOH$196Pennsylvania: median $259 across 76 hospitalsPA$259New Jersey: median $229 across 32 hospitalsNJ$229Connecticut: median $337 across 20 hospitalsCT$337Rhode Island: 6 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $139 across 128 hospitalsCA$139Utah: median $479 across 34 hospitalsUT$479Colorado: median $246 across 46 hospitalsCO$246Nebraska: median $216 across 49 hospitalsNE$216Missouri: median $205 across 58 hospitalsMO$205Kentucky: median $166 across 45 hospitalsKY$166West Virginia: median $145 across 25 hospitalsWV$145Virginia: median $234 across 65 hospitalsVA$234Maryland: median $234 across 39 hospitalsMD$234Delaware: 6 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $260 across 27 hospitalsAZ$260New Mexico: median $80 across 16 hospitalsNM$80Kansas: median $287 across 42 hospitalsKS$287Arkansas: median $152 across 21 hospitalsAR$152Tennessee: median $105 across 59 hospitalsTN$105North Carolina: median $248 across 73 hospitalsNC$248South Carolina: median $217 across 41 hospitalsSC$217Oklahoma: median $109 across 41 hospitalsOK$109Louisiana: median $82 across 37 hospitalsLA$82Mississippi: median $83 across 36 hospitalsMS$83Alabama: median $206 across 26 hospitalsAL$206Georgia: median $365 across 71 hospitalsGA$365Hawaii: median $208 across 17 hospitalsHI$208Texas: median $222 across 172 hospitalsTX$222Florida: median $134 across 115 hospitalsFL$134
Cash price by state, most expensive first. National median $210. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT34$479+128%$261 – $563
Georgia GA71$365+74%$215 – $511
Connecticut CT20$337+60%$102 – $337
Illinois IL96$328+56%$144 – $552
New Hampshire NH12$323+54%$95 – $719
Kansas KS42$287+37%$122 – $420
Iowa IA46$279+33%$159 – $314
Arizona AZ27$260+24%$101 – $524
Pennsylvania PA76$259+23%$78 – $491
Wisconsin WI83$258+23%$241 – $466
Minnesota MN73$254+21%$101 – $321
Oregon OR37$252+20%$112 – $303
North Carolina NC73$248+18%$119 – $437
Colorado CO46$246+17%$105 – $304
Montana MT11$239+14%$135 – $305
Maryland MD39$234+11%$175 – $481
Virginia VA65$234+11%$125 – $319
New Jersey NJ32$229+9%$57 – $480
Texas TX172$222+6%$146 – $533
South Carolina SC41$217+3%$120 – $309
Massachusetts MA41$217+3%$156 – $344
Nebraska NE49$216+3%$150 – $344
New York NY67$2090%$89 – $426
Hawaii HI17$208−1%$80 – $327
North Dakota ND12$206−2%$177 – $289
Alabama AL26$206−2%$95 – $431
Missouri MO58$205−2%$89 – $280
Ohio OH117$196−7%$133 – $435
Idaho ID19$175−17%$113 – $379
Kentucky KY45$166−21%$102 – $190
Indiana IN74$164−22%$106 – $264
Washington WA45$158−25%$86 – $306
Arkansas AR21$152−28%$72 – $241
Michigan MI66$151−28%$89 – $241
West Virginia WV25$145−31%$49 – $210
California CA128$139−34%$87 – $307
Florida FL115$134−36%$70 – $375
Maine ME27$124−41%$88 – $281
Oklahoma OK41$109−48%$19 – $242
Tennessee TN59$105−50%$81 – $252
Mississippi MS36$83−60%$55 – $116
Louisiana LA37$82−61%$48 – $204
New Mexico NM16$80−62%$72 – $139
Nevada NV9not enough hospitals filed a usable price
South Dakota SD8not enough hospitals filed a usable price
Alaska AK7not enough hospitals filed a usable price
Vermont VT7not enough hospitals filed a usable price
Delaware DE6not enough hospitals filed a usable price
Rhode Island RI6not enough hospitals filed a usable price
Wyoming WY6not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $210.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,808$207$101 – $388
Children’s46$193$113 – $394
Critical access423$222$112 – $327
Ownership
For-profit327$220$114 – $531
Government282$187$88 – $318
Non-profit1,668$212$103 – $375
System affiliation
Part of a system1,974$215$106 – $383
Independent312$175$85 – $331

Cash price vs list price

Median list price (chargemaster)$346
Median cash price$210
Cash as a share of list, median hospital64%

At the typical hospital, asking for the cash price cuts the list price by about 37%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,656 hospitals filed a usable inpatient cash price for this code. The median is $211 and the average of the middle 60% is $221; most fall between $108 and $384.

Cash price percentiles, inpatient, across 1,656 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$76$123$211$344$524

The most expensive tenth of hospitals charges at least 6.9× what the cheapest tenth charges ($76 vs $524).

Of the 1,832 hospitals that filed this code inpatient, 1,656 gave a usable cash price; 106 carried a plausibility flag, 1 filed a number their own filing marks as not a price, 0 gave an estimate, and 69 a list price only.

How complete is this

2,286 of the 3,956 hospitals with a price file in our corpus (58%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 2,526 hospitals that filed this code at all gave us
Usable cash price — counted2,286
Cash price carrying a plausibility flag — shown on the compare tool, excluded here114
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded123
Hospitals that filed this code2,526

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as INSITU HYBRIDIZATION (FISH).

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Probe test on tissue for one more target (CPT 88364) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-88364-probe-test-on-tissue-for-one-more-target