HRHospitalRates.comCompare prices

Procedure price report · Pathology

Prenatal blood screen for trisomy 21, 18 and 13

CPT 81507the billing code this page is about

Sequencing of fetal DNA found in a pregnant person's blood sample, reported as a risk score for Down syndrome and two other chromosome conditions.

Hospitals typically charge $875 cash for this outpatient procedure — the median across 261 hospitals that filed a usable cash price; the average of the middle 60% is $1,048. Most fall between $553 and $1,814 (20th–80th percentile).

Hospitals
261
States
32
Filings dated
Mar 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 261 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$387$639$875$1,528$2,114

The most expensive tenth of hospitals charges at least 5.5× what the cheapest tenth charges ($387 vs $2,114).

How the prices are spread

$276 – $349: 14 hospitals$276$349 – $440: 8 hospitals$440 – $555: 22 hospitals$440$555 – $700: 23 hospitals$700 – $883: 59 hospitals$700$883 – $1,114: 35 hospitals$1,114 – $1,406: 18 hospitals$1,114$1,406 – $1,774: 12 hospitals$1,774 – $2,239: 35 hospitals$1,774$2,239 – $2,824: 20 hospitals$2,239median $875price bands are equal on a log scale
Hospitals per price band (246 of 261 — the bands cover the 5th to 95th percentile)
FromToHospitals
$276$34914
$349$4408
$440$55522
$555$70023
$700$88359
$883$1,11435
$1,114$1,40618
$1,406$1,77412
$1,774$2,23935
$2,239$2,82420

By state

The median cash price in each state, against the national median of $875.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: 9 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: 2 hospitals filed a usable price — fewer than 10, so no figureIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: 1 hospital filed a usable price — fewer than 10, so no figureMNIllinois: median $578 across 21 hospitalsIL$578Wisconsin: median $2,824 across 21 hospitalsWI$2,824Michigan: median $276 across 14 hospitalsMI$276New York: median $795 across 25 hospitalsNY$795Massachusetts: 1 hospital filed a usable price — fewer than 10, so no figureMAOregon: 7 hospitals filed a usable price — fewer than 10, so no figureORNevada: 3 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: no hospital in the corpus filed a usable priceIAIndiana: 2 hospitals filed a usable price — fewer than 10, so no figureINOhio: 2 hospitals filed a usable price — fewer than 10, so no figureOHPennsylvania: median $1,490 across 29 hospitalsPA$1,490New Jersey: median $875 across 23 hospitalsNJ$875Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $1,814 across 23 hospitalsCA$1,814Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: no hospital in the corpus filed a usable priceCONebraska: no hospital in the corpus filed a usable priceNEMissouri: 1 hospital filed a usable price — fewer than 10, so no figureMOKentucky: no hospital in the corpus filed a usable priceKYWest Virginia: no hospital in the corpus filed a usable priceWVVirginia: no hospital in the corpus filed a usable priceVAMaryland: no hospital in the corpus filed a usable priceMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 1 hospital filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: 4 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: no hospital in the corpus filed a usable priceARTennessee: 1 hospital filed a usable price — fewer than 10, so no figureTNNorth Carolina: 2 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: 2 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: 3 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 6 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 6 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: no hospital in the corpus filed a usable priceGAHawaii: 1 hospital filed a usable price — fewer than 10, so no figureHITexas: median $699 across 43 hospitalsTX$699Florida: 3 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $875. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Wisconsin WI21$2,824+223%$1,480 – $2,824
California CA23$1,814+107%$1,814 – $1,814
Pennsylvania PA29$1,490+70%$404 – $2,113
New Jersey NJ23$8750%$795 – $875
New York NY25$795−9%$795 – $2,330
Texas TX43$699−20%$540 – $1,077
Illinois IL21$578−34%$578 – $881
Michigan MI14$276−68%$276 – $1,097
Washington WA9not enough hospitals filed a usable price
Oregon OR7not enough hospitals filed a usable price
Louisiana LA6not enough hospitals filed a usable price
Mississippi MS6not enough hospitals filed a usable price
Kansas KS4not enough hospitals filed a usable price
Florida FL3not enough hospitals filed a usable price
Nevada NV3not enough hospitals filed a usable price
Oklahoma OK3not enough hospitals filed a usable price
Idaho ID2not enough hospitals filed a usable price
Indiana IN2not enough hospitals filed a usable price
North Carolina NC2not enough hospitals filed a usable price
Ohio OH2not enough hospitals filed a usable price
South Carolina SC2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Arizona AZ1not enough hospitals filed a usable price
Hawaii HI1not enough hospitals filed a usable price
Massachusetts MA1not enough hospitals filed a usable price
Minnesota MN1not enough hospitals filed a usable price
Missouri MO1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Tennessee TN1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $875.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care227$875$560 – $1,814
Children’s3fewer than 20 hospitals
Critical access31$1,250$540 – $2,114
Ownership
For-profit18fewer than 20 hospitals
Government34$795$286 – $1,392
Non-profit209$881$557 – $1,814
System affiliation
Part of a system229$875$540 – $1,814
Independent32$1,170$795 – $1,695

Cash price vs list price

Median list price (chargemaster)$1,795
Median cash price$875
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

174 hospitals filed a usable inpatient cash price for this code. The median is $1,077 and the average of the middle 60% is $1,217; most fall between $540 and $2,113.

Cash price percentiles, inpatient, across 174 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$319$540$1,077$1,814$2,385

The most expensive tenth of hospitals charges at least 7.5× what the cheapest tenth charges ($319 vs $2,385).

Of the 194 hospitals that filed this code inpatient, 174 gave a usable cash price; 2 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 18 a list price only.

How complete is this

261 of the 3,956 hospitals with a price file in our corpus (7%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 281 hospitals that filed this code at all gave us
Usable cash price — counted261
Cash price carrying a plausibility flag — shown on the compare tool, excluded here3
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded15
Hospitals that filed this code281

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as FETAL ANEUPLOIDY TRISOM RISK.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Prenatal blood screen for trisomy 21, 18 and 13 (CPT 81507) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81507-prenatal-blood-screen-for-trisomy-21-18-and-13