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Procedure price report · Pathology

Ovarian cancer risk blood test, two proteins

CPT 81500the billing code this page is about

Blood test that measures two proteins and combines the results with menopausal status to report a score estimating the chance that an ovarian mass is cancer.

Hospitals typically charge $426 cash for this outpatient procedure — the median across 457 hospitals that filed a usable cash price; the average of the middle 60% is $431. Most fall between $261 and $696 (20th–80th percentile).

Hospitals
457
States
43
Filings dated
Mar 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 457 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$208$261$426$594$1,138

The most expensive tenth of hospitals charges at least 5.5× what the cheapest tenth charges ($208 vs $1,138).

How the prices are spread

$146 – $182: 14 hospitals$146$182 – $226: 31 hospitals$226 – $281: 52 hospitals$226$281 – $350: 53 hospitals$350 – $436: 74 hospitals$350$436 – $543: 59 hospitals$543 – $675: 52 hospitals$543$675 – $841: 38 hospitals$841 – $1,047: 11 hospitals$841$1,047 – $1,303: 30 hospitals$1,047median $426price bands are equal on a log scale
Hospitals per price band (414 of 457 — the bands cover the 5th to 95th percentile)
FromToHospitals
$146$18214
$182$22631
$226$28152
$281$35053
$350$43674
$436$54359
$543$67552
$675$84138
$841$1,04711
$1,047$1,30330

By state

The median cash price in each state, against the national median of $426.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: 9 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: 1 hospital filed a usable price — fewer than 10, so no figureIDMontana: 2 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: 1 hospital filed a usable price — fewer than 10, so no figureMNIllinois: median $547 across 24 hospitalsIL$547Wisconsin: median $1,235 across 15 hospitalsWI$1,235Michigan: median $359 across 12 hospitalsMI$359New York: median $261 across 28 hospitalsNY$261Massachusetts: 9 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 1 hospital filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 2 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $250 across 13 hospitalsIA$250Indiana: median $398 across 14 hospitalsIN$398Ohio: median $454 across 10 hospitalsOH$454Pennsylvania: median $391 across 35 hospitalsPA$391New Jersey: median $287 across 42 hospitalsNJ$287Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 3 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $594 across 24 hospitalsCA$594Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: 3 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 1 hospital filed a usable price — fewer than 10, so no figureNEMissouri: 7 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $442 across 19 hospitalsKY$442West Virginia: median $521 across 18 hospitalsWV$521Virginia: median $257 across 29 hospitalsVA$257Maryland: 7 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: 3 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 2 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 2 hospitals filed a usable price — fewer than 10, so no figureNMKansas: no hospital in the corpus filed a usable priceKSArkansas: no hospital in the corpus filed a usable priceARTennessee: median $216 across 10 hospitalsTN$216North Carolina: median $426 across 25 hospitalsNC$426South Carolina: median $399 across 13 hospitalsSC$399Oklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: median $498 across 14 hospitalsLA$498Mississippi: 7 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: median $428 across 23 hospitalsGA$428Hawaii: no hospital in the corpus filed a usable priceHITexas: 9 hospitals filed a usable price — fewer than 10, so no figureTXFlorida: 6 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $426. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Wisconsin WI15$1,235+190%$1,088 – $1,235
California CA24$594+40%$521 – $594
Illinois IL24$547+29%$215 – $912
West Virginia WV18$521+22%$519 – $557
Louisiana LA14$498+17%$217 – $718
Ohio OH10$454+7%$336 – $684
Kentucky KY19$442+4%$311 – $717
Georgia GA23$428+1%$428 – $451
North Carolina NC25$4260%$282 – $511
South Carolina SC13$399−6%$399 – $399
Indiana IN14$398−7%$316 – $553
Pennsylvania PA35$391−8%$180 – $2,632
Michigan MI12$359−16%$292 – $1,235
New Jersey NJ42$287−33%$261 – $300
New York NY28$261−39%$261 – $457
Virginia VA29$257−40%$221 – $676
Iowa IA13$250−41%$250 – $250
Tennessee TN10$216−49%$120 – $399
Massachusetts MA9not enough hospitals filed a usable price
Texas TX9not enough hospitals filed a usable price
Washington WA9not enough hospitals filed a usable price
Maryland MD7not enough hospitals filed a usable price
Missouri MO7not enough hospitals filed a usable price
Mississippi MS7not enough hospitals filed a usable price
Florida FL6not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Colorado CO3not enough hospitals filed a usable price
Delaware DE3not enough hospitals filed a usable price
Rhode Island RI3not enough hospitals filed a usable price
Arizona AZ2not enough hospitals filed a usable price
Montana MT2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
New Mexico NM2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Wyoming WY2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Idaho ID1not enough hospitals filed a usable price
Minnesota MN1not enough hospitals filed a usable price
Nebraska NE1not enough hospitals filed a usable price
Oregon OR1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $426.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care385$412$260 – $676
Children’s1fewer than 20 hospitals
Critical access70$521$332 – $1,138
Ownership
For-profit46$442$316 – $807
Government62$300$190 – $573
Non-profit348$427$261 – $696
System affiliation
Part of a system399$426$261 – $676
Independent58$430$260 – $782

Cash price vs list price

Median list price (chargemaster)$782
Median cash price$426
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

284 hospitals filed a usable inpatient cash price for this code. The median is $435 and the average of the middle 60% is $458; most fall between $261 and $723.

Cash price percentiles, inpatient, across 284 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$221$300$435$667$1,235

The most expensive tenth of hospitals charges at least 5.6× what the cheapest tenth charges ($221 vs $1,235).

Of the 303 hospitals that filed this code inpatient, 284 gave a usable cash price; 13 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 6 a list price only.

How complete is this

457 of the 3,956 hospitals with a price file in our corpus (12%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 487 hospitals that filed this code at all gave us
Usable cash price — counted457
Cash price carrying a plausibility flag — shown on the compare tool, excluded here17
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded12
Hospitals that filed this code487

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as Hc Onco (Ovarian) Biochemical Assay Two Proteins.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Ovarian cancer risk blood test, two proteins (CPT 81500) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81500-ovarian-cancer-risk-blood-test-two-proteins