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Procedure price report · Pathology

Full mitochondrial genome sequencing

CPT 81460the billing code this page is about

Laboratory test that reads the entire DNA sequence of the mitochondria, including detection of mixtures of normal and altered mitochondrial DNA, used when a mitochondrial disorder is suspected.

Hospitals typically charge $1,480 cash for this outpatient procedure — the median across 554 hospitals that filed a usable cash price; the average of the middle 60% is $1,593. Most fall between $774 and $2,920 (20th–80th percentile).

Hospitals
554
States
47
Filings dated
Dec 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 554 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$479$858$1,480$2,616$4,038

The most expensive tenth of hospitals charges at least 8.4× what the cheapest tenth charges ($479 vs $4,038).

How the prices are spread

$310 – $419: 11 hospitals$310$419 – $567: 41 hospitals$567 – $767: 30 hospitals$567$767 – $1,038: 70 hospitals$1,038 – $1,404: 79 hospitals$1,038$1,404 – $1,899: 102 hospitals$1,899 – $2,569: 53 hospitals$1,899$2,569 – $3,475: 69 hospitals$3,475 – $4,701: 30 hospitals$3,475$4,701 – $6,359: 20 hospitals$4,701median $1,480price bands are equal on a log scale
Hospitals per price band (505 of 554 — the bands cover the 5th to 95th percentile)
FromToHospitals
$310$41911
$419$56741
$567$76730
$767$1,03870
$1,038$1,40479
$1,404$1,899102
$1,899$2,56953
$2,569$3,47569
$3,475$4,70130
$4,701$6,35920

By state

The median cash price in each state, against the national median of $1,480.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: 2 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: 9 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: 2 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: 2 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $823 across 20 hospitalsMN$823Illinois: median $2,703 across 21 hospitalsIL$2,703Wisconsin: median $2,272 across 26 hospitalsWI$2,272Michigan: 4 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $1,931 across 36 hospitalsNY$1,931Massachusetts: median $3,861 across 14 hospitalsMA$3,861Oregon: 4 hospitals filed a usable price — fewer than 10, so no figureORNevada: 5 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $1,236 across 11 hospitalsIA$1,236Indiana: median $1,853 across 16 hospitalsIN$1,853Ohio: median $1,689 across 37 hospitalsOH$1,689Pennsylvania: median $1,241 across 25 hospitalsPA$1,241New Jersey: median $1,416 across 32 hospitalsNJ$1,416Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $2,940 across 28 hospitalsCA$2,940Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: median $662 across 15 hospitalsCO$662Nebraska: 1 hospital filed a usable price — fewer than 10, so no figureNEMissouri: 5 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $2,092 across 14 hospitalsKY$2,092West Virginia: 4 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $1,652 across 12 hospitalsVA$1,652Maryland: median $288 across 16 hospitalsMD$288Delaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 5 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 7 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 4 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $1,652 across 19 hospitalsTN$1,652North Carolina: median $763 across 10 hospitalsNC$763South Carolina: median $2,223 across 12 hospitalsSC$2,223Oklahoma: 6 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: median $711 across 12 hospitalsLA$711Mississippi: 3 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: median $1,385 across 16 hospitalsGA$1,385Hawaii: no hospital in the corpus filed a usable priceHITexas: median $785 across 67 hospitalsTX$785Florida: median $1,287 across 16 hospitalsFL$1,287
Cash price by state, most expensive first. National median $1,480. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Massachusetts MA14$3,861+161%$3,378 – $5,357
California CA28$2,940+99%$777 – $2,940
Illinois IL21$2,703+83%$2,479 – $2,852
Wisconsin WI26$2,272+54%$842 – $10,753
South Carolina SC12$2,223+50%$2,223 – $2,223
Kentucky KY14$2,092+41%$1,210 – $6,359
New York NY36$1,931+30%$1,287 – $3,422
Indiana IN16$1,853+25%$1,385 – $2,504
Ohio OH37$1,689+14%$1,532 – $4,038
Tennessee TN19$1,652+12%$1,257 – $1,673
Virginia VA12$1,652+12%$1,652 – $2,780
New Jersey NJ32$1,416−4%$1,287 – $1,416
Georgia GA16$1,385−6%$1,385 – $1,716
Florida FL16$1,287−13%$490 – $1,829
Pennsylvania PA25$1,241−16%$194 – $2,176
Iowa IA11$1,236−17%$1,236 – $1,236
Minnesota MN20$823−44%$701 – $937
Texas TX67$785−47%$479 – $1,052
North Carolina NC10$763−48%$763 – $763
Louisiana LA12$711−52%$396 – $1,352
Colorado CO15$662−55%$515 – $1,323
Maryland MD16$288−81%$236 – $1,573
Washington WA9not enough hospitals filed a usable price
Kansas KS7not enough hospitals filed a usable price
Oklahoma OK6not enough hospitals filed a usable price
Arizona AZ5not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Missouri MO5not enough hospitals filed a usable price
Nevada NV5not enough hospitals filed a usable price
Arkansas AR4not enough hospitals filed a usable price
Michigan MI4not enough hospitals filed a usable price
Oregon OR4not enough hospitals filed a usable price
West Virginia WV4not enough hospitals filed a usable price
Mississippi MS3not enough hospitals filed a usable price
Idaho ID2not enough hospitals filed a usable price
Maine ME2not enough hospitals filed a usable price
North Dakota ND2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
Nebraska NE1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $1,480.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care460$1,480$777 – $2,852
Children’s28$1,106$300 – $1,969
Critical access62$1,621$842 – $3,010
Ownership
For-profit31$1,385$1,010 – $3,335
Government68$1,055$564 – $1,769
Non-profit451$1,621$823 – $2,940
System affiliation
Part of a system501$1,430$763 – $2,852
Independent53$1,500$1,001 – $3,219

Cash price vs list price

Median list price (chargemaster)$2,661
Median cash price$1,480
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

410 hospitals filed a usable inpatient cash price for this code. The median is $1,480 and the average of the middle 60% is $1,611; most fall between $763 and $2,940.

Cash price percentiles, inpatient, across 410 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$479$823$1,480$2,780$4,378

The most expensive tenth of hospitals charges at least 9.1× what the cheapest tenth charges ($479 vs $4,378).

Of the 443 hospitals that filed this code inpatient, 410 gave a usable cash price; 26 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 7 a list price only.

How complete is this

554 of the 3,956 hospitals with a price file in our corpus (14%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 601 hospitals that filed this code at all gave us
Usable cash price — counted554
Cash price carrying a plausibility flag — shown on the compare tool, excluded here38
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded7
Hospitals that filed this code601

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as WHOLE MITOCHONDRIAL GENOME.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Full mitochondrial genome sequencing (CPT 81460) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81460-full-mitochondrial-genome-sequencing