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Procedure price report · Pathology

Solid tumor test for microsatellite instability

CPT 81457the billing code this page is about

A laboratory DNA test on solid tumor tissue that measures microsatellite instability, a pattern of repeated DNA errors in the tumor; billed once per test.

Hospitals typically charge $1,722 cash for this outpatient procedure — the median across 446 hospitals that filed a usable cash price; the average of the middle 60% is $1,725. Most fall between $880 and $3,139 (20th–80th percentile).

Hospitals
446
States
38
Filings dated
Apr 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 446 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$744$897$1,722$2,691$4,314

The most expensive tenth of hospitals charges at least 5.8× what the cheapest tenth charges ($744 vs $4,314).

How the prices are spread

$448 – $571: 16 hospitals$448$571 – $727: 10 hospitals$727 – $925: 101 hospitals$727$925 – $1,178: 27 hospitals$1,178 – $1,499: 10 hospitals$1,178$1,499 – $1,908: 69 hospitals$1,908 – $2,429: 64 hospitals$1,908$2,429 – $3,092: 45 hospitals$3,092 – $3,937: 30 hospitals$3,092$3,937 – $5,011: 41 hospitals$3,937median $1,722price bands are equal on a log scale
Hospitals per price band (413 of 446 — the bands cover the 5th to 95th percentile)
FromToHospitals
$448$57116
$571$72710
$727$925101
$925$1,17827
$1,178$1,49910
$1,499$1,90869
$1,908$2,42964
$2,429$3,09245
$3,092$3,93730
$3,937$5,01141

By state

The median cash price in each state, against the national median of $1,722.

Alaska: no hospital in the corpus filed a usable priceAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: 1 hospital filed a usable price — fewer than 10, so no figureWAIdaho: no hospital in the corpus filed a usable priceIDMontana: 2 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 3 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $1,565 across 23 hospitalsMN$1,565Illinois: median $1,832 across 13 hospitalsIL$1,832Wisconsin: median $1,982 across 35 hospitalsWI$1,982Michigan: median $1,020 across 16 hospitalsMI$1,020New York: median $897 across 24 hospitalsNY$897Massachusetts: median $2,785 across 10 hospitalsMA$2,785Oregon: no hospital in the corpus filed a usable priceORNevada: no hospital in the corpus filed a usable priceNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: 3 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $861 across 12 hospitalsIA$861Indiana: median $942 across 17 hospitalsIN$942Ohio: median $3,900 across 24 hospitalsOH$3,900Pennsylvania: median $213 across 11 hospitalsPA$213New Jersey: median $897 across 16 hospitalsNJ$897Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $895 across 22 hospitalsCA$895Utah: no hospital in the corpus filed a usable priceUTColorado: median $823 across 14 hospitalsCO$823Nebraska: 2 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 6 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: no hospital in the corpus filed a usable priceKYWest Virginia: no hospital in the corpus filed a usable priceWVVirginia: median $1,174 across 13 hospitalsVA$1,174Maryland: 7 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 5 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: no hospital in the corpus filed a usable priceARTennessee: 2 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: median $2,333 across 13 hospitalsNC$2,333South Carolina: median $9,371 across 18 hospitalsSC$9,371Oklahoma: median $448 across 12 hospitalsOK$448Louisiana: 6 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 5 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: median $1,658 across 32 hospitalsGA$1,658Hawaii: no hospital in the corpus filed a usable priceHITexas: median $1,632 across 50 hospitalsTX$1,632Florida: median $880 across 14 hospitalsFL$880
Cash price by state, most expensive first. National median $1,722. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Carolina SC18$9,371+444%$3,396 – $9,371
Ohio OH24$3,900+126%$3,900 – $4,030
Massachusetts MA10$2,785+62%$588 – $2,785
North Carolina NC13$2,333+35%$2,295 – $2,333
Wisconsin WI35$1,982+15%$761 – $5,011
Illinois IL13$1,832+6%$1,772 – $1,832
Georgia GA32$1,658−4%$1,658 – $4,563
Texas TX50$1,632−5%$913 – $2,187
Minnesota MN23$1,565−9%$744 – $2,526
Virginia VA13$1,174−32%$942 – $2,296
Michigan MI16$1,020−41%$1,020 – $1,722
Indiana IN17$942−45%$710 – $1,998
New Jersey NJ16$897−48%$897 – $4,148
New York NY24$897−48%$897 – $2,298
California CA22$895−48%$895 – $895
Florida FL14$880−49%$880 – $1,764
Iowa IA12$861−50%$861 – $861
Colorado CO14$823−52%$823 – $1,295
Oklahoma OK12$448−74%$448 – $448
Pennsylvania PA11$213−88%$180 – $458
Maryland MD7not enough hospitals filed a usable price
Louisiana LA6not enough hospitals filed a usable price
Missouri MO6not enough hospitals filed a usable price
Kansas KS5not enough hospitals filed a usable price
Mississippi MS5not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
North Dakota ND3not enough hospitals filed a usable price
South Dakota SD3not enough hospitals filed a usable price
Montana MT2not enough hospitals filed a usable price
Nebraska NE2not enough hospitals filed a usable price
Tennessee TN2not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Washington WA1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $1,722.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care378$1,722$895 – $2,785
Children’s5fewer than 20 hospitals
Critical access61$1,565$761 – $4,011
Ownership
For-profit26$1,658$880 – $2,452
Government58$1,658$897 – $2,601
Non-profit360$1,737$861 – $3,396
System affiliation
Part of a system410$1,658$880 – $3,139
Independent36$1,903$1,031 – $2,838

Cash price vs list price

Median list price (chargemaster)$2,854
Median cash price$1,722
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

363 hospitals filed a usable inpatient cash price for this code. The median is $2,152 and the average of the middle 60% is $2,043; most fall between $882 and $3,900.

Cash price percentiles, inpatient, across 363 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$753$895$2,152$3,406$5,011

The most expensive tenth of hospitals charges at least 6.7× what the cheapest tenth charges ($753 vs $5,011).

Of the 379 hospitals that filed this code inpatient, 363 gave a usable cash price; 14 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 2 a list price only.

How complete is this

446 of the 3,956 hospitals with a price file in our corpus (11%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 461 hospitals that filed this code at all gave us
Usable cash price — counted446
Cash price carrying a plausibility flag — shown on the compare tool, excluded here8
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded5
Hospitals that filed this code461

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as SO NEO GSAP DNA MCRSTL INS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Solid tumor test for microsatellite instability (CPT 81457) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81457-solid-tumor-test-for-microsatellite-instability