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Procedure price report · Pathology

Cancer gene panel, 51 or more genes, DNA testing

CPT 81455the billing code this page is about

A large laboratory panel on solid tumor or blood cancer tissue that examines 51 or more genes for DNA changes, and in some versions combined DNA and RNA changes; billed once for the panel.

Hospitals typically charge $2,955 cash for this outpatient procedure — the median across 1,342 hospitals that filed a usable cash price; the average of the middle 60% is $3,166. Most fall between $1,602 and $5,994 (20th–80th percentile).

Hospitals
1,342
States
49
Filings dated
Sep 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,342 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$1,149$1,797$2,955$4,817$7,884

The most expensive tenth of hospitals charges at least 6.9× what the cheapest tenth charges ($1,149 vs $7,884).

How the prices are spread

$905 – $1,150: 71 hospitals$905$1,150 – $1,462: 84 hospitals$1,462 – $1,857: 120 hospitals$1,462$1,857 – $2,360: 165 hospitals$2,360 – $2,999: 173 hospitals$2,360$2,999 – $3,811: 181 hospitals$3,811 – $4,842: 150 hospitals$3,811$4,842 – $6,153: 84 hospitals$6,153 – $7,819: 113 hospitals$6,153$7,819 – $9,936: 69 hospitals$7,819median $2,955price bands are equal on a log scale
Hospitals per price band (1,210 of 1,342 — the bands cover the 5th to 95th percentile)
FromToHospitals
$905$1,15071
$1,150$1,46284
$1,462$1,857120
$1,857$2,360165
$2,360$2,999173
$2,999$3,811181
$3,811$4,842150
$4,842$6,15384
$6,153$7,819113
$7,819$9,93669

By state

The median cash price in each state, against the national median of $2,955.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 8 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 4 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $2,742 across 10 hospitalsNH$2,742Washington: median $2,498 across 32 hospitalsWA$2,498Idaho: median $2,449 across 11 hospitalsID$2,449Montana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: 2 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $1,584 across 50 hospitalsMN$1,584Illinois: median $3,191 across 53 hospitalsIL$3,191Wisconsin: median $3,014 across 72 hospitalsWI$3,014Michigan: median $3,723 across 34 hospitalsMI$3,723New York: median $4,250 across 53 hospitalsNY$4,250Massachusetts: median $7,038 across 29 hospitalsMA$7,038Oregon: median $2,243 across 21 hospitalsOR$2,243Nevada: 8 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $2,803 across 17 hospitalsIA$2,803Indiana: median $3,177 across 46 hospitalsIN$3,177Ohio: median $3,197 across 76 hospitalsOH$3,197Pennsylvania: median $5,739 across 61 hospitalsPA$5,739New Jersey: median $3,212 across 29 hospitalsNJ$3,212Connecticut: median $3,650 across 15 hospitalsCT$3,650Rhode Island: 6 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $4,785 across 54 hospitalsCA$4,785Utah: median $4,095 across 25 hospitalsUT$4,095Colorado: median $4,039 across 31 hospitalsCO$4,039Nebraska: median $1,456 across 15 hospitalsNE$1,456Missouri: median $4,380 across 28 hospitalsMO$4,380Kentucky: median $3,523 across 30 hospitalsKY$3,523West Virginia: 9 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $2,987 across 40 hospitalsVA$2,987Maryland: median $2,308 across 28 hospitalsMD$2,308Delaware: 2 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $4,290 across 25 hospitalsAZ$4,290New Mexico: 7 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $1,962 across 18 hospitalsKS$1,962Arkansas: 9 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $3,677 across 30 hospitalsTN$3,677North Carolina: median $1,860 across 28 hospitalsNC$1,860South Carolina: median $2,228 across 33 hospitalsSC$2,228Oklahoma: median $1,599 across 25 hospitalsOK$1,599Louisiana: median $1,659 across 19 hospitalsLA$1,659Mississippi: median $1,773 across 17 hospitalsMS$1,773Alabama: median $2,175 across 13 hospitalsAL$2,175Georgia: median $1,941 across 61 hospitalsGA$1,941Hawaii: 1 hospital filed a usable price — fewer than 10, so no figureHITexas: median $2,331 across 87 hospitalsTX$2,331Florida: median $2,005 across 62 hospitalsFL$2,005
Cash price by state, most expensive first. National median $2,955. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Massachusetts MA29$7,038+138%$3,594 – $9,936
Pennsylvania PA61$5,739+94%$3,358 – $7,553
California CA54$4,785+62%$1,900 – $6,675
Missouri MO28$4,380+48%$1,752 – $6,066
Arizona AZ25$4,290+45%$2,873 – $7,519
New York NY53$4,250+44%$2,920 – $8,464
Utah UT25$4,095+39%$4,095 – $4,817
Colorado CO31$4,039+37%$2,398 – $5,255
Michigan MI34$3,723+26%$2,846 – $5,609
Tennessee TN30$3,677+24%$1,705 – $3,747
Connecticut CT15$3,650+24%$2,836 – $5,761
Kentucky KY30$3,523+19%$1,810 – $10,875
New Jersey NJ29$3,212+9%$2,531 – $3,358
Ohio OH76$3,197+8%$1,915 – $6,845
Illinois IL53$3,191+8%$1,735 – $6,412
Indiana IN46$3,177+8%$1,920 – $5,574
Wisconsin WI72$3,014+2%$1,620 – $6,553
Virginia VA40$2,987+1%$1,592 – $4,380
Iowa IA17$2,803−5%$1,924 – $2,803
New Hampshire NH10$2,742−7%$1,028 – $2,950
Washington WA32$2,498−15%$893 – $3,328
Idaho ID11$2,449−17%$2,406 – $3,990
Texas TX87$2,331−21%$1,088 – $3,284
Maryland MD28$2,308−22%$426 – $4,237
Oregon OR21$2,243−24%$2,069 – $2,378
South Carolina SC33$2,228−25%$2,003 – $6,047
Alabama AL13$2,175−26%$1,487 – $6,495
Florida FL62$2,005−32%$1,125 – $3,036
Kansas KS18$1,962−34%$1,232 – $6,874
Georgia GA61$1,941−34%$1,373 – $7,745
North Carolina NC28$1,860−37%$1,786 – $2,562
Mississippi MS17$1,773−40%$1,149 – $1,960
Louisiana LA19$1,659−44%$1,012 – $3,468
Oklahoma OK25$1,599−46%$1,260 – $3,011
Minnesota MN50$1,584−46%$640 – $3,503
Nebraska NE15$1,456−51%$1,149 – $2,660
Arkansas AR9not enough hospitals filed a usable price
West Virginia WV9not enough hospitals filed a usable price
Maine ME8not enough hospitals filed a usable price
Nevada NV8not enough hospitals filed a usable price
New Mexico NM7not enough hospitals filed a usable price
Rhode Island RI6not enough hospitals filed a usable price
Vermont VT4not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Delaware DE2not enough hospitals filed a usable price
North Dakota ND2not enough hospitals filed a usable price
Hawaii HI1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $2,955.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,125$2,920$1,599 – $6,047
Children’s36$2,574$1,350 – $4,921
Critical access172$3,197$1,620 – $6,135
Ownership
For-profit131$3,352$1,703 – $7,519
Government150$2,337$1,373 – $4,736
Non-profit1,052$3,014$1,628 – $5,948
System affiliation
Part of a system1,190$2,987$1,599 – $6,066
Independent152$2,847$1,628 – $5,200

Cash price vs list price

Median list price (chargemaster)$5,035
Median cash price$2,955
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,062 hospitals filed a usable inpatient cash price for this code. The median is $3,014 and the average of the middle 60% is $3,242; most fall between $1,620 and $6,047.

Cash price percentiles, inpatient, across 1,062 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$1,125$1,797$3,014$5,048$7,553

The most expensive tenth of hospitals charges at least 6.7× what the cheapest tenth charges ($1,125 vs $7,553).

Of the 1,202 hospitals that filed this code inpatient, 1,062 gave a usable cash price; 99 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 41 a list price only.

How complete is this

1,342 of the 3,956 hospitals with a price file in our corpus (34%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,512 hospitals that filed this code at all gave us
Usable cash price — counted1,342
Cash price carrying a plausibility flag — shown on the compare tool, excluded here126
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded43
Hospitals that filed this code1,512

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as SO/HL 51/>GSAP DNA/DNA&RNA.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Cancer gene panel, 51 or more genes, DNA testing (CPT 81455) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81455-cancer-gene-panel-51-or-more-genes-dna-testing