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Procedure price report · Pathology

Solid tumor gene panel, 5 to 50 genes, RNA testing

CPT 81449the billing code this page is about

A laboratory test on tumor tissue that analyzes RNA from 5 to 50 genes, mainly to detect gene fusions and rearrangements in a solid tumor; billed once for the panel.

Hospitals typically charge $1,009 cash for this outpatient procedure — the median across 457 hospitals that filed a usable cash price; the average of the middle 60% is $993. Most fall between $658 and $1,655 (20th–80th percentile).

Hospitals
457
States
43
Filings dated
Nov 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 23, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 457 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$463$688$1,009$1,324$2,296

The most expensive tenth of hospitals charges at least 5.0× what the cheapest tenth charges ($463 vs $2,296).

How the prices are spread

$356 – $440: 21 hospitals$356$440 – $544: 18 hospitals$544 – $674: 44 hospitals$544$674 – $833: 100 hospitals$833 – $1,031: 35 hospitals$833$1,031 – $1,276: 70 hospitals$1,276 – $1,578: 54 hospitals$1,276$1,578 – $1,953: 24 hospitals$1,953 – $2,416: 31 hospitals$1,953$2,416 – $2,990: 17 hospitals$2,416median $1,009price bands are equal on a log scale
Hospitals per price band (414 of 457 — the bands cover the 5th to 95th percentile)
FromToHospitals
$356$44021
$440$54418
$544$67444
$674$833100
$833$1,03135
$1,031$1,27670
$1,276$1,57854
$1,578$1,95324
$1,953$2,41631
$2,416$2,99017

By state

The median cash price in each state, against the national median of $1,009.

Alaska: no hospital in the corpus filed a usable priceAKMaine: 2 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $1,069 across 16 hospitalsWA$1,069Idaho: 1 hospital filed a usable price — fewer than 10, so no figureIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $1,056 across 12 hospitalsMN$1,056Illinois: median $2,255 across 15 hospitalsIL$2,255Wisconsin: median $1,080 across 13 hospitalsWI$1,080Michigan: 4 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $717 across 23 hospitalsNY$717Massachusetts: 9 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 3 hospitals filed a usable price — fewer than 10, so no figureORNevada: 3 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $792 across 12 hospitalsIA$792Indiana: median $794 across 17 hospitalsIN$794Ohio: 5 hospitals filed a usable price — fewer than 10, so no figureOHPennsylvania: median $688 across 35 hospitalsPA$688New Jersey: median $658 across 25 hospitalsNJ$658Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 6 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $689 across 35 hospitalsCA$689Utah: no hospital in the corpus filed a usable priceUTColorado: 5 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 2 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 9 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 3 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: 2 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $1,884 across 16 hospitalsVA$1,884Maryland: median $1,089 across 15 hospitalsMD$1,089Delaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: 6 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 6 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: median $1,301 across 11 hospitalsNC$1,301South Carolina: median $1,166 across 12 hospitalsSC$1,166Oklahoma: median $359 across 12 hospitalsOK$359Louisiana: 3 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: median $466 across 10 hospitalsMS$466Alabama: 3 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $816 across 17 hospitalsGA$816Hawaii: no hospital in the corpus filed a usable priceHITexas: median $1,014 across 48 hospitalsTX$1,014Florida: median $735 across 26 hospitalsFL$735
Cash price by state, most expensive first. National median $1,009. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Illinois IL15$2,255+123%$1,258 – $2,255
Virginia VA16$1,884+87%$942 – $2,296
North Carolina NC11$1,301+29%$1,301 – $1,301
South Carolina SC12$1,166+16%$1,166 – $1,166
Maryland MD15$1,089+8%$643 – $1,267
Wisconsin WI13$1,080+7%$1,080 – $2,178
Washington WA16$1,069+6%$816 – $1,655
Minnesota MN12$1,056+5%$900 – $1,056
Texas TX48$1,014+1%$370 – $1,323
Georgia GA17$816−19%$816 – $1,324
Indiana IN17$794−21%$707 – $1,484
Iowa IA12$792−22%$792 – $792
Florida FL26$735−27%$525 – $1,046
New York NY23$717−29%$598 – $2,613
California CA35$689−32%$689 – $1,041
Pennsylvania PA35$688−32%$321 – $13,837
New Jersey NJ25$658−35%$598 – $658
Mississippi MS10$466−54%$408 – $854
Oklahoma OK12$359−64%$312 – $587
Massachusetts MA9not enough hospitals filed a usable price
Missouri MO9not enough hospitals filed a usable price
Arkansas AR6not enough hospitals filed a usable price
Rhode Island RI6not enough hospitals filed a usable price
Tennessee TN6not enough hospitals filed a usable price
Colorado CO5not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Ohio OH5not enough hospitals filed a usable price
Michigan MI4not enough hospitals filed a usable price
Alabama AL3not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
Kentucky KY3not enough hospitals filed a usable price
Louisiana LA3not enough hospitals filed a usable price
Nevada NV3not enough hospitals filed a usable price
Oregon OR3not enough hospitals filed a usable price
Maine ME2not enough hospitals filed a usable price
Nebraska NE2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
West Virginia WV2not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Idaho ID1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $1,009.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care413$942$637 – $1,655
Children’s5fewer than 20 hospitals
Critical access38$1,056$796 – $1,794
Ownership
For-profit42$1,303$723 – $1,794
Government48$735$556 – $1,301
Non-profit366$1,014$658 – $1,794
System affiliation
Part of a system427$1,014$650 – $1,655
Independent30$897$688 – $1,484

Cash price vs list price

Median list price (chargemaster)$1,941
Median cash price$1,009
Cash as a share of list, median hospital59%

At the typical hospital, asking for the cash price cuts the list price by about 41%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

353 hospitals filed a usable inpatient cash price for this code. The median is $1,056 and the average of the middle 60% is $1,095; most fall between $689 and $1,884.

Cash price percentiles, inpatient, across 353 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$408$717$1,056$1,487$2,374

The most expensive tenth of hospitals charges at least 5.8× what the cheapest tenth charges ($408 vs $2,374).

Of the 384 hospitals that filed this code inpatient, 353 gave a usable cash price; 23 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 8 a list price only.

How complete is this

457 of the 3,956 hospitals with a price file in our corpus (12%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 486 hospitals that filed this code at all gave us
Usable cash price — counted457
Cash price carrying a plausibility flag — shown on the compare tool, excluded here18
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded11
Hospitals that filed this code486

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 23, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as SO NEO GSAP 5-50 RNA ALYS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Solid tumor gene panel, 5 to 50 genes, RNA testing (CPT 81449) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81449-solid-tumor-gene-panel-5-to-50-genes-rna-testing