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Procedure price report · Pathology

Whole genome DNA sequencing, each family member compared

CPT 81426the billing code this page is about

Genome sequencing of one relative, such as a parent, used for comparison with the patient's result; billed once for each additional person tested.

Hospitals typically charge $2,823 cash for this outpatient procedure — the median across 408 hospitals that filed a usable cash price; the average of the middle 60% is $2,829. Most fall between $1,374 and $4,439 (20th–80th percentile).

Hospitals
408
States
37
Filings dated
Sep 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 408 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$869$1,620$2,823$3,780$5,510

The most expensive tenth of hospitals charges at least 6.3× what the cheapest tenth charges ($869 vs $5,510).

How the prices are spread

$360 – $478: 9 hospitals$360$478 – $636: 4 hospitals$636 – $845: 7 hospitals$636$845 – $1,123: 23 hospitals$1,123 – $1,493: 25 hospitals$1,123$1,493 – $1,985: 52 hospitals$1,985 – $2,638: 36 hospitals$1,985$2,638 – $3,506: 113 hospitals$3,506 – $4,660: 48 hospitals$3,506$4,660 – $6,194: 63 hospitals$4,660median $2,823price bands are equal on a log scale
Hospitals per price band (380 of 408 — the bands cover the 5th to 95th percentile)
FromToHospitals
$360$4789
$478$6364
$636$8457
$845$1,12323
$1,123$1,49325
$1,493$1,98552
$1,985$2,63836
$2,638$3,506113
$3,506$4,66048
$4,660$6,19463

By state

The median cash price in each state, against the national median of $2,823.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: 9 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $1,760 across 11 hospitalsMN$1,760Illinois: median $3,539 across 12 hospitalsIL$3,539Wisconsin: median $1,800 across 13 hospitalsWI$1,800Michigan: median $1,271 across 14 hospitalsMI$1,271New York: median $2,710 across 20 hospitalsNY$2,710Massachusetts: 2 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 2 hospitals filed a usable price — fewer than 10, so no figureORNevada: 1 hospital filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $2,602 across 11 hospitalsIA$2,602Indiana: median $3,901 across 13 hospitalsIN$3,901Ohio: median $5,081 across 26 hospitalsOH$5,081Pennsylvania: median $4,397 across 27 hospitalsPA$4,397New Jersey: median $2,981 across 24 hospitalsNJ$2,981Connecticut: 1 hospital filed a usable price — fewer than 10, so no figureCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $6,194 across 26 hospitalsCA$6,194Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: 1 hospital filed a usable price — fewer than 10, so no figureCONebraska: no hospital in the corpus filed a usable priceNEMissouri: 4 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 8 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: 1 hospital filed a usable price — fewer than 10, so no figureWVVirginia: median $3,083 across 11 hospitalsVA$3,083Maryland: median $1,436 across 13 hospitalsMD$1,436Delaware: no hospital in the corpus filed a usable priceDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 2 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $3,478 across 12 hospitalsTN$3,478North Carolina: median $300 across 26 hospitalsNC$300South Carolina: median $2,925 across 12 hospitalsSC$2,925Oklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: median $1,565 across 16 hospitalsLA$1,565Mississippi: 3 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: no hospital in the corpus filed a usable priceALGeorgia: 5 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $3,250 across 58 hospitalsTX$3,250Florida: median $360 across 14 hospitalsFL$360
Cash price by state, most expensive first. National median $2,823. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA26$6,194+119%$2,700 – $6,194
Ohio OH26$5,081+80%$4,268 – $5,554
Pennsylvania PA27$4,397+56%$2,113 – $4,439
Indiana IN13$3,901+38%$3,383 – $5,272
Illinois IL12$3,539+25%$2,602 – $3,539
Tennessee TN12$3,478+23%$2,823 – $3,523
Texas TX58$3,250+15%$1,620 – $3,250
Virginia VA11$3,083+9%$1,541 – $3,083
New Jersey NJ24$2,981+6%$2,710 – $2,981
South Carolina SC12$2,925+4%$2,925 – $2,925
New York NY20$2,710−4%$2,710 – $4,439
Iowa IA11$2,602−8%$2,602 – $2,602
Wisconsin WI13$1,800−36%$1,800 – $3,130
Minnesota MN11$1,760−38%$1,760 – $1,760
Louisiana LA16$1,565−45%$1,029 – $2,623
Maryland MD13$1,436−49%$1,032 – $1,959
Michigan MI14$1,271−55%$1,271 – $3,740
Florida FL14$360−87%$360 – $1,284
North Carolina NC26$300−89%$300 – $4,877
Washington WA9not enough hospitals filed a usable price
Kentucky KY8not enough hospitals filed a usable price
Georgia GA5not enough hospitals filed a usable price
Missouri MO4not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
Mississippi MS3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Kansas KS2not enough hospitals filed a usable price
Massachusetts MA2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Oregon OR2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Colorado CO1not enough hospitals filed a usable price
Connecticut CT1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
Nevada NV1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price
West Virginia WV1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $2,823.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care341$2,925$1,395 – $4,439
Children’s24$2,253$1,001 – $2,901
Critical access43$2,936$1,271 – $4,877
Ownership
For-profit32$3,250$1,374 – $5,081
Government43$2,215$360 – $3,478
Non-profit333$2,925$1,503 – $4,439
System affiliation
Part of a system387$2,823$1,355 – $4,439
Independent21$3,054$1,737 – $3,736

Cash price vs list price

Median list price (chargemaster)$4,500
Median cash price$2,823
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

270 hospitals filed a usable inpatient cash price for this code. The median is $2,925 and the average of the middle 60% is $2,959; most fall between $1,544 and $4,877.

Cash price percentiles, inpatient, across 270 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$995$1,760$2,925$4,439$6,127

The most expensive tenth of hospitals charges at least 6.2× what the cheapest tenth charges ($995 vs $6,127).

Of the 308 hospitals that filed this code inpatient, 270 gave a usable cash price; 31 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 7 a list price only.

How complete is this

408 of the 3,956 hospitals with a price file in our corpus (10%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 434 hospitals that filed this code at all gave us
Usable cash price — counted408
Cash price carrying a plausibility flag — shown on the compare tool, excluded here18
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded6
Hospitals that filed this code434

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as GENOME SEQUENCE ANALYSIS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Whole genome DNA sequencing, each family member compared (CPT 81426) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81426-whole-genome-dna-sequencing-each-family-member-compared