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Procedure price report · Pathology

Prenatal blood test for small missing chromosome pieces

CPT 81422the billing code this page is about

Analysis of fetal DNA in the pregnant patient's blood to look for microdeletions, meaning very small missing chromosome segments; billed once per test.

Hospitals typically charge $785 cash for this outpatient procedure — the median across 517 hospitals that filed a usable cash price; the average of the middle 60% is $881. Most fall between $394 and $1,541 (20th–80th percentile).

Hospitals
517
States
43
Filings dated
Dec 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 517 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$197$502$785$1,505$2,194

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($197 vs $2,194).

How the prices are spread

$110 – $153: 20 hospitals$110$153 – $214: 12 hospitals$214 – $300: 31 hospitals$214$300 – $419: 21 hospitals$419 – $585: 53 hospitals$419$585 – $818: 111 hospitals$818 – $1,144: 70 hospitals$818$1,144 – $1,598: 83 hospitals$1,598 – $2,234: 42 hospitals$1,598$2,234 – $3,122: 25 hospitals$2,234median $785price bands are equal on a log scale
Hospitals per price band (468 of 517 — the bands cover the 5th to 95th percentile)
FromToHospitals
$110$15320
$153$21412
$214$30031
$300$41921
$419$58553
$585$818111
$818$1,14470
$1,144$1,59883
$1,598$2,23442
$2,234$3,12225

By state

The median cash price in each state, against the national median of $785.

Alaska: 7 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 7 hospitals filed a usable price — fewer than 10, so no figureMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 5 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $678 across 20 hospitalsWA$678Idaho: 3 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: no hospital in the corpus filed a usable priceMNIllinois: median $993 across 20 hospitalsIL$993Wisconsin: median $1,207 across 10 hospitalsWI$1,207Michigan: median $127 across 17 hospitalsMI$127New York: median $759 across 24 hospitalsNY$759Massachusetts: 7 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 4 hospitals filed a usable price — fewer than 10, so no figureORNevada: 3 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $1,518 across 11 hospitalsIA$1,518Indiana: median $661 across 18 hospitalsIN$661Ohio: median $1,209 across 30 hospitalsOH$1,209Pennsylvania: median $1,139 across 24 hospitalsPA$1,139New Jersey: median $835 across 34 hospitalsNJ$835Connecticut: 2 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $1,736 across 22 hospitalsCA$1,736Utah: median $1,310 across 26 hospitalsUT$1,310Colorado: median $515 across 15 hospitalsCO$515Nebraska: 3 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $699 across 20 hospitalsMO$699Kentucky: median $1,130 across 16 hospitalsKY$1,130West Virginia: 1 hospital filed a usable price — fewer than 10, so no figureWVVirginia: median $695 across 14 hospitalsVA$695Maryland: median $396 across 11 hospitalsMD$396Delaware: 2 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 2 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 2 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 9 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 6 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: median $287 across 29 hospitalsNC$287South Carolina: 1 hospital filed a usable price — fewer than 10, so no figureSCOklahoma: 8 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 8 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: no hospital in the corpus filed a usable priceMSAlabama: 3 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $1,235 across 19 hospitalsGA$1,235Hawaii: 1 hospital filed a usable price — fewer than 10, so no figureHITexas: median $1,017 across 26 hospitalsTX$1,017Florida: median $644 across 25 hospitalsFL$644
Cash price by state, most expensive first. National median $785. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA22$1,736+121%$1,736 – $1,736
Iowa IA11$1,518+93%$1,518 – $1,518
Utah UT26$1,310+67%$1,310 – $1,541
Georgia GA19$1,235+57%$465 – $1,235
Ohio OH30$1,209+54%$502 – $1,592
Wisconsin WI10$1,207+54%$880 – $1,298
Pennsylvania PA24$1,139+45%$243 – $8,109
Kentucky KY16$1,130+44%$731 – $2,552
Texas TX26$1,017+30%$699 – $1,017
Illinois IL20$993+26%$949 – $1,518
New Jersey NJ34$835+6%$759 – $835
New York NY24$759−3%$716 – $997
Missouri MO20$699−11%$77 – $1,674
Virginia VA14$695−11%$347 – $695
Washington WA20$678−14%$559 – $1,586
Indiana IN18$661−16%$541 – $1,408
Florida FL25$644−18%$426 – $1,514
Colorado CO15$515−34%$509 – $798
Maryland MD11$396−49%$357 – $518
North Carolina NC29$287−63%$97 – $422
Michigan MI17$127−84%$127 – $1,047
Arkansas AR9not enough hospitals filed a usable price
Louisiana LA8not enough hospitals filed a usable price
Oklahoma OK8not enough hospitals filed a usable price
Alaska AK7not enough hospitals filed a usable price
Massachusetts MA7not enough hospitals filed a usable price
Maine ME7not enough hospitals filed a usable price
Tennessee TN6not enough hospitals filed a usable price
New Hampshire NH5not enough hospitals filed a usable price
Oregon OR4not enough hospitals filed a usable price
Alabama AL3not enough hospitals filed a usable price
Idaho ID3not enough hospitals filed a usable price
Nebraska NE3not enough hospitals filed a usable price
Nevada NV3not enough hospitals filed a usable price
Arizona AZ2not enough hospitals filed a usable price
Connecticut CT2not enough hospitals filed a usable price
Delaware DE2not enough hospitals filed a usable price
Kansas KS2not enough hospitals filed a usable price
Hawaii HI1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
South Carolina SC1not enough hospitals filed a usable price
West Virginia WV1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $785.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care441$785$422 – $1,592
Children’s5fewer than 20 hospitals
Critical access70$741$118 – $1,310
Ownership
For-profit33$970$401 – $2,277
Government67$699$287 – $1,138
Non-profit416$798$420 – $1,592
System affiliation
Part of a system473$759$385 – $1,541
Independent44$873$416 – $1,822

Cash price vs list price

Median list price (chargemaster)$1,712
Median cash price$785
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

343 hospitals filed a usable inpatient cash price for this code. The median is $940 and the average of the middle 60% is $1,008; most fall between $451 and $1,674.

Cash price percentiles, inpatient, across 343 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$287$512$940$1,541$2,194

The most expensive tenth of hospitals charges at least 7.7× what the cheapest tenth charges ($287 vs $2,194).

Of the 382 hospitals that filed this code inpatient, 343 gave a usable cash price; 23 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 16 a list price only.

How complete is this

517 of the 3,956 hospitals with a price file in our corpus (13%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 573 hospitals that filed this code at all gave us
Usable cash price — counted517
Cash price carrying a plausibility flag — shown on the compare tool, excluded here40
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded15
Hospitals that filed this code573

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as FETAL CHRMOML MICRODELTJ.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Prenatal blood test for small missing chromosome pieces (CPT 81422) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81422-prenatal-blood-test-for-small-missing-chromosome-pieces