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Procedure price report · Pathology

Prenatal blood test for fetal chromosome conditions

CPT 81420the billing code this page is about

Analysis of fetal DNA circulating in the pregnant patient's blood to assess the chance of extra or missing chromosomes, such as trisomy 21; billed once per test.

Hospitals typically charge $1,011 cash for this outpatient procedure — the median across 1,302 hospitals that filed a usable cash price; the average of the middle 60% is $1,103. Most fall between $504 and $2,000 (20th–80th percentile).

Hospitals
1,302
States
50
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,302 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$376$602$1,011$1,736$2,846

The most expensive tenth of hospitals charges at least 7.6× what the cheapest tenth charges ($376 vs $2,846).

How the prices are spread

$297 – $382: 72 hospitals$297$382 – $491: 112 hospitals$491 – $631: 95 hospitals$491$631 – $811: 169 hospitals$811 – $1,043: 146 hospitals$811$1,043 – $1,341: 157 hospitals$1,341 – $1,723: 151 hospitals$1,341$1,723 – $2,215: 110 hospitals$2,215 – $2,848: 95 hospitals$2,215$2,848 – $3,661: 66 hospitals$2,848median $1,011price bands are equal on a log scale
Hospitals per price band (1,173 of 1,302 — the bands cover the 5th to 95th percentile)
FromToHospitals
$297$38272
$382$491112
$491$63195
$631$811169
$811$1,043146
$1,043$1,341157
$1,341$1,723151
$1,723$2,215110
$2,215$2,84895
$2,848$3,66166

By state

The median cash price in each state, against the national median of $1,011.

Alaska: median $1,538 across 13 hospitalsAK$1,538Maine: median $1,055 across 14 hospitalsME$1,055Vermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 6 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $766 across 51 hospitalsWA$766Idaho: median $469 across 13 hospitalsID$469Montana: 3 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $1,275 across 10 hospitalsND$1,275Minnesota: 8 hospitals filed a usable price — fewer than 10, so no figureMNIllinois: median $1,160 across 71 hospitalsIL$1,160Wisconsin: median $978 across 41 hospitalsWI$978Michigan: median $300 across 33 hospitalsMI$300New York: median $870 across 58 hospitalsNY$870Massachusetts: median $2,047 across 30 hospitalsMA$2,047Oregon: median $741 across 24 hospitalsOR$741Nevada: 9 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 6 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 4 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $730 across 26 hospitalsIA$730Indiana: median $846 across 31 hospitalsIN$846Ohio: median $1,456 across 80 hospitalsOH$1,456Pennsylvania: median $1,644 across 66 hospitalsPA$1,644New Jersey: median $835 across 45 hospitalsNJ$835Connecticut: 7 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $1,736 across 31 hospitalsCA$1,736Utah: median $543 across 32 hospitalsUT$543Colorado: median $984 across 19 hospitalsCO$984Nebraska: 9 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $1,166 across 37 hospitalsMO$1,166Kentucky: median $1,288 across 36 hospitalsKY$1,288West Virginia: median $916 across 20 hospitalsWV$916Virginia: median $827 across 46 hospitalsVA$827Maryland: median $759 across 24 hospitalsMD$759Delaware: 5 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $2,575 across 14 hospitalsAZ$2,575New Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $1,792 across 24 hospitalsKS$1,792Arkansas: median $1,337 across 16 hospitalsAR$1,337Tennessee: median $1,030 across 18 hospitalsTN$1,030North Carolina: median $681 across 51 hospitalsNC$681South Carolina: median $1,709 across 29 hospitalsSC$1,709Oklahoma: median $1,217 across 19 hospitalsOK$1,217Louisiana: median $548 across 18 hospitalsLA$548Mississippi: median $625 across 15 hospitalsMS$625Alabama: median $898 across 12 hospitalsAL$898Georgia: median $968 across 21 hospitalsGA$968Hawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $870 across 87 hospitalsTX$870Florida: median $498 across 61 hospitalsFL$498
Cash price by state, most expensive first. National median $1,011. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Arizona AZ14$2,575+155%$591 – $2,575
Massachusetts MA30$2,047+103%$1,541 – $2,931
Kansas KS24$1,792+77%$1,154 – $2,611
California CA31$1,736+72%$759 – $1,736
South Carolina SC29$1,709+69%$1,436 – $1,808
Pennsylvania PA66$1,644+63%$759 – $3,622
Alaska AK13$1,538+52%$718 – $2,087
Ohio OH80$1,456+44%$602 – $3,404
Arkansas AR16$1,337+32%$547 – $1,579
Kentucky KY36$1,288+27%$731 – $2,165
North Dakota ND10$1,275+26%$811 – $1,366
Oklahoma OK19$1,217+20%$572 – $1,754
Missouri MO37$1,166+15%$764 – $1,674
Illinois IL71$1,160+15%$573 – $2,027
Maine ME14$1,055+4%$461 – $2,255
Tennessee TN18$1,030+2%$595 – $1,639
Colorado CO19$984−3%$847 – $1,612
Wisconsin WI41$978−3%$463 – $2,333
Georgia GA21$968−4%$600 – $1,788
West Virginia WV20$916−9%$675 – $2,124
Alabama AL12$898−11%$779 – $1,431
New York NY58$870−14%$695 – $2,288
Texas TX87$870−14%$621 – $1,500
Indiana IN31$846−16%$670 – $1,288
New Jersey NJ45$835−17%$759 – $873
Virginia VA46$827−18%$405 – $1,903
Washington WA51$766−24%$425 – $1,284
Maryland MD24$759−25%$388 – $2,762
Oregon OR24$741−27%$504 – $1,892
Iowa IA26$730−28%$729 – $1,593
North Carolina NC51$681−33%$117 – $1,148
Mississippi MS15$625−38%$359 – $721
Louisiana LA18$548−46%$338 – $1,660
Utah UT32$543−46%$461 – $866
Florida FL61$498−51%$366 – $2,199
Idaho ID13$469−54%$461 – $1,670
Michigan MI33$300−70%$130 – $1,044
Nebraska NE9not enough hospitals filed a usable price
Nevada NV9not enough hospitals filed a usable price
Minnesota MN8not enough hospitals filed a usable price
Connecticut CT7not enough hospitals filed a usable price
New Hampshire NH6not enough hospitals filed a usable price
Wyoming WY6not enough hospitals filed a usable price
Delaware DE5not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
South Dakota SD4not enough hospitals filed a usable price
Montana MT3not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $1,011.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,040$948$469 – $1,903
Children’s7fewer than 20 hospitals
Critical access251$1,200$646 – $2,233
Ownership
For-profit136$1,011$600 – $2,189
Government195$1,002$562 – $1,811
Non-profit967$1,010$477 – $2,000
System affiliation
Part of a system1,104$957$477 – $1,998
Independent198$1,262$638 – $2,040

Cash price vs list price

Median list price (chargemaster)$1,875
Median cash price$1,011
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

909 hospitals filed a usable inpatient cash price for this code. The median is $1,121 and the average of the middle 60% is $1,172; most fall between $518 and $2,199.

Cash price percentiles, inpatient, across 909 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$400$602$1,121$1,808$3,321

The most expensive tenth of hospitals charges at least 8.3× what the cheapest tenth charges ($400 vs $3,321).

Of the 990 hospitals that filed this code inpatient, 909 gave a usable cash price; 44 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 37 a list price only.

How complete is this

1,302 of the 3,956 hospitals with a price file in our corpus (33%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,415 hospitals that filed this code at all gave us
Usable cash price — counted1,302
Cash price carrying a plausibility flag — shown on the compare tool, excluded here70
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded41
Hospitals that filed this code1,415

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as FETAL CHRMOML ANEUPLOIDY.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Prenatal blood test for fetal chromosome conditions (CPT 81420) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81420-prenatal-blood-test-for-fetal-chromosome-conditions