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Procedure price report · Pathology

Tissue-type matching, detailed, class I, one allele group

CPT 81381the billing code this page is about

High-resolution HLA typing reported for a single allele or allele group, such as the HLA-B*57:01 marker checked before starting abacavir.

Hospitals typically charge $264 cash for this outpatient procedure — the median across 2,037 hospitals that filed a usable cash price; the average of the middle 60% is $282. Most fall between $138 and $500 (20th–80th percentile).

Hospitals
2,037
States
50
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 2,037 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$94$164$264$437$792

The most expensive tenth of hospitals charges at least 8.4× what the cheapest tenth charges ($94 vs $792).

How the prices are spread

$69 – $92: 91 hospitals$69$92 – $124: 126 hospitals$124 – $166: 217 hospitals$124$166 – $222: 311 hospitals$222 – $298: 292 hospitals$222$298 – $399: 321 hospitals$399 – $535: 220 hospitals$399$535 – $717: 114 hospitals$717 – $961: 112 hospitals$717$961 – $1,287: 32 hospitals$961median $264price bands are equal on a log scale
Hospitals per price band (1,836 of 2,037 — the bands cover the 5th to 95th percentile)
FromToHospitals
$69$9291
$92$124126
$124$166217
$166$222311
$222$298292
$298$399321
$399$535220
$535$717114
$717$961112
$961$1,28732

By state

The median cash price in each state, against the national median of $264.

Alaska: median $279 across 13 hospitalsAK$279Maine: median $241 across 17 hospitalsME$241Vermont: 5 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $309 across 17 hospitalsNH$309Washington: median $272 across 51 hospitalsWA$272Idaho: median $296 across 10 hospitalsID$296Montana: 6 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $321 across 14 hospitalsND$321Minnesota: median $256 across 49 hospitalsMN$256Illinois: median $291 across 94 hospitalsIL$291Wisconsin: median $325 across 65 hospitalsWI$325Michigan: median $234 across 63 hospitalsMI$234New York: median $249 across 81 hospitalsNY$249Massachusetts: median $429 across 42 hospitalsMA$429Oregon: median $272 across 26 hospitalsOR$272Nevada: median $248 across 11 hospitalsNV$248Wyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: median $467 across 11 hospitalsSD$467Iowa: median $208 across 32 hospitalsIA$208Indiana: median $258 across 73 hospitalsIN$258Ohio: median $303 across 106 hospitalsOH$303Pennsylvania: median $470 across 97 hospitalsPA$470New Jersey: median $187 across 54 hospitalsNJ$187Connecticut: median $506 across 16 hospitalsCT$506Rhode Island: 8 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $150 across 90 hospitalsCA$150Utah: median $1,599 across 32 hospitalsUT$1,599Colorado: median $267 across 32 hospitalsCO$267Nebraska: median $186 across 14 hospitalsNE$186Missouri: median $285 across 63 hospitalsMO$285Kentucky: median $295 across 38 hospitalsKY$295West Virginia: median $125 across 28 hospitalsWV$125Virginia: median $326 across 61 hospitalsVA$326Maryland: median $164 across 32 hospitalsMD$164Delaware: 6 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $423 across 27 hospitalsAZ$423New Mexico: median $255 across 12 hospitalsNM$255Kansas: median $321 across 23 hospitalsKS$321Arkansas: median $240 across 22 hospitalsAR$240Tennessee: median $166 across 53 hospitalsTN$166North Carolina: median $189 across 64 hospitalsNC$189South Carolina: median $492 across 37 hospitalsSC$492Oklahoma: median $292 across 35 hospitalsOK$292Louisiana: median $234 across 35 hospitalsLA$234Mississippi: median $124 across 39 hospitalsMS$124Alabama: median $232 across 22 hospitalsAL$232Georgia: median $317 across 65 hospitalsGA$317Hawaii: median $237 across 13 hospitalsHI$237Texas: median $283 across 136 hospitalsTX$283Florida: median $135 across 93 hospitalsFL$135
Cash price by state, most expensive first. National median $264. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT32$1,599+506%$536 – $1,881
Connecticut CT16$506+92%$206 – $574
South Carolina SC37$492+86%$215 – $875
Pennsylvania PA97$470+78%$195 – $982
South Dakota SD11$467+77%$382 – $768
Massachusetts MA42$429+63%$335 – $629
Arizona AZ27$423+60%$195 – $792
Virginia VA61$326+24%$137 – $500
Wisconsin WI65$325+23%$180 – $802
North Dakota ND14$321+22%$265 – $466
Kansas KS23$321+21%$125 – $458
Georgia GA65$317+20%$195 – $407
New Hampshire NH17$309+17%$134 – $460
Ohio OH106$303+15%$164 – $513
Idaho ID10$296+12%$199 – $388
Kentucky KY38$295+12%$138 – $443
Oklahoma OK35$292+11%$106 – $364
Illinois IL94$291+10%$150 – $559
Missouri MO63$285+8%$156 – $365
Texas TX136$283+7%$193 – $360
Alaska AK13$279+6%$179 – $829
Oregon OR26$272+3%$250 – $415
Washington WA51$272+3%$217 – $404
Colorado CO32$267+1%$196 – $437
Indiana IN73$258−2%$170 – $361
Minnesota MN49$256−3%$60 – $421
New Mexico NM12$255−4%$182 – $546
New York NY81$249−6%$170 – $498
Nevada NV11$248−6%$49 – $595
Maine ME17$241−9%$136 – $431
Arkansas AR22$240−9%$61 – $364
Hawaii HI13$237−10%$224 – $601
Michigan MI63$234−11%$94 – $802
Louisiana LA35$234−11%$130 – $429
Alabama AL22$232−12%$109 – $388
Iowa IA32$208−21%$163 – $370
North Carolina NC64$189−28%$39 – $502
New Jersey NJ54$187−29%$170 – $277
Nebraska NE14$186−30%$85 – $389
Tennessee TN53$166−37%$122 – $228
Maryland MD32$164−38%$120 – $318
California CA90$150−43%$69 – $386
Florida FL93$135−49%$81 – $449
West Virginia WV28$125−53%$125 – $449
Mississippi MS39$124−53%$99 – $206
Rhode Island RI8not enough hospitals filed a usable price
Delaware DE6not enough hospitals filed a usable price
Montana MT6not enough hospitals filed a usable price
Vermont VT5not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $264.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,643$250$135 – $492
Children’s30$350$150 – $617
Critical access355$304$191 – $502
Ownership
For-profit258$295$131 – $664
Government272$237$125 – $458
Non-profit1,498$265$146 – $492
System affiliation
Part of a system1,740$264$138 – $502
Independent297$255$146 – $473

Cash price vs list price

Median list price (chargemaster)$510
Median cash price$264
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,467 hospitals filed a usable inpatient cash price for this code. The median is $283 and the average of the middle 60% is $302; most fall between $156 and $517.

Cash price percentiles, inpatient, across 1,467 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$100$175$283$476$802

The most expensive tenth of hospitals charges at least 8.0× what the cheapest tenth charges ($100 vs $802).

Of the 1,630 hospitals that filed this code inpatient, 1,467 gave a usable cash price; 91 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 72 a list price only.

How complete is this

2,037 of the 3,956 hospitals with a price file in our corpus (51%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 2,235 hospitals that filed this code at all gave us
Usable cash price — counted2,037
Cash price carrying a plausibility flag — shown on the compare tool, excluded here120
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded77
Hospitals that filed this code2,235

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Hla-B 5701 Genotype, Pgx.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Tissue-type matching, detailed, class I, one allele group (CPT 81381) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81381-tissue-type-matching-detailed-class-i-one-allele-group