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Procedure price report · Pathology

Tissue-type matching, detailed, A, B, C and DRB1

CPT 81378the billing code this page is about

High-resolution HLA typing that identifies the specific alleles of the A, B, C and DRB1 markers, commonly required for stem cell and bone marrow donor matching.

Hospitals typically charge $804 cash for this outpatient procedure — the median across 627 hospitals that filed a usable cash price; the average of the middle 60% is $887. Most fall between $371 and $1,877 (20th–80th percentile).

Hospitals
627
States
46
Filings dated
Aug 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 627 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$332$393$804$1,610$3,126

The most expensive tenth of hospitals charges at least 9.4× what the cheapest tenth charges ($332 vs $3,126).

How the prices are spread

$259 – $348: 79 hospitals$259$348 – $467: 95 hospitals$467 – $628: 65 hospitals$467$628 – $843: 52 hospitals$843 – $1,132: 86 hospitals$843$1,132 – $1,521: 46 hospitals$1,521 – $2,042: 63 hospitals$1,521$2,042 – $2,743: 32 hospitals$2,743 – $3,684: 35 hospitals$2,743$3,684 – $4,947: 12 hospitals$3,684median $804price bands are equal on a log scale
Hospitals per price band (565 of 627 — the bands cover the 5th to 95th percentile)
FromToHospitals
$259$34879
$348$46795
$467$62865
$628$84352
$843$1,13286
$1,132$1,52146
$1,521$2,04263
$2,042$2,74332
$2,743$3,68435
$3,684$4,94712

By state

The median cash price in each state, against the national median of $804.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 5 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $553 across 20 hospitalsWA$553Idaho: no hospital in the corpus filed a usable priceIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $373 across 23 hospitalsMN$373Illinois: median $882 across 23 hospitalsIL$882Wisconsin: 3 hospitals filed a usable price — fewer than 10, so no figureWIMichigan: median $477 across 13 hospitalsMI$477New York: median $849 across 41 hospitalsNY$849Massachusetts: 8 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 8 hospitals filed a usable price — fewer than 10, so no figureORNevada: 6 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureSDIowa: median $332 across 12 hospitalsIA$332Indiana: median $472 across 18 hospitalsIN$472Ohio: median $914 across 43 hospitalsOH$914Pennsylvania: median $749 across 39 hospitalsPA$749New Jersey: median $380 across 29 hospitalsNJ$380Connecticut: 6 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 3 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $7,336 across 27 hospitalsCA$7,336Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: median $166 across 10 hospitalsCO$166Nebraska: 2 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 9 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $1,448 across 14 hospitalsKY$1,448West Virginia: median $804 across 16 hospitalsWV$804Virginia: median $1,096 across 25 hospitalsVA$1,096Maryland: median $1,474 across 13 hospitalsMD$1,474Delaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: median $1,549 across 16 hospitalsAZ$1,549New Mexico: 2 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 2 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 6 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $371 across 22 hospitalsTN$371North Carolina: median $605 across 25 hospitalsNC$605South Carolina: median $3,606 across 16 hospitalsSC$3,606Oklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 7 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 3 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 2 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $1,129 across 14 hospitalsGA$1,129Hawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $1,459 across 51 hospitalsTX$1,459Florida: median $264 across 35 hospitalsFL$264
Cash price by state, most expensive first. National median $804. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA27$7,336+812%$3,477 – $7,336
South Carolina SC16$3,606+349%$1,074 – $3,606
Arizona AZ16$1,549+93%$470 – $2,183
Maryland MD13$1,474+83%$1,214 – $1,965
Texas TX51$1,459+82%$1,030 – $1,730
Kentucky KY14$1,448+80%$772 – $2,888
Georgia GA14$1,129+40%$380 – $1,129
Virginia VA25$1,096+36%$371 – $1,143
Ohio OH43$914+14%$644 – $1,610
Illinois IL23$882+10%$332 – $1,903
New York NY41$849+6%$346 – $1,072
West Virginia WV16$8040%$471 – $804
Pennsylvania PA39$749−7%$397 – $2,453
North Carolina NC25$605−25%$548 – $756
Washington WA20$553−31%$553 – $1,341
Michigan MI13$477−41%$398 – $3,542
Indiana IN18$472−41%$443 – $1,371
New Jersey NJ29$380−53%$346 – $397
Minnesota MN23$373−54%$279 – $482
Tennessee TN22$371−54%$338 – $582
Iowa IA12$332−59%$332 – $332
Florida FL35$264−67%$233 – $872
Colorado CO10$166−79%$166 – $653
Missouri MO9not enough hospitals filed a usable price
Massachusetts MA8not enough hospitals filed a usable price
Oregon OR8not enough hospitals filed a usable price
Louisiana LA7not enough hospitals filed a usable price
Arkansas AR6not enough hospitals filed a usable price
Connecticut CT6not enough hospitals filed a usable price
Nevada NV6not enough hospitals filed a usable price
New Hampshire NH5not enough hospitals filed a usable price
Mississippi MS3not enough hospitals filed a usable price
Rhode Island RI3not enough hospitals filed a usable price
Wisconsin WI3not enough hospitals filed a usable price
Alabama AL2not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
Kansas KS2not enough hospitals filed a usable price
Nebraska NE2not enough hospitals filed a usable price
New Mexico NM2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
South Dakota SD1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $804.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care547$798$371 – $1,770
Children’s25$2,453$374 – $3,416
Critical access51$804$415 – $1,023
Ownership
For-profit52$1,441$489 – $2,718
Government66$548$346 – $1,202
Non-profit505$804$371 – $1,877
System affiliation
Part of a system580$804$371 – $1,788
Independent47$727$374 – $1,918

Cash price vs list price

Median list price (chargemaster)$1,608
Median cash price$804
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

423 hospitals filed a usable inpatient cash price for this code. The median is $914 and the average of the middle 60% is $1,002; most fall between $380 and $2,070.

Cash price percentiles, inpatient, across 423 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$332$423$914$1,730$3,606

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($332 vs $3,606).

Of the 474 hospitals that filed this code inpatient, 423 gave a usable cash price; 35 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 16 a list price only.

How complete is this

627 of the 3,956 hospitals with a price file in our corpus (16%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 681 hospitals that filed this code at all gave us
Usable cash price — counted627
Cash price carrying a plausibility flag — shown on the compare tool, excluded here34
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded19
Hospitals that filed this code681

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as Hcc Hla-a, B, C & Drb1 High Resolution.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Tissue-type matching, detailed, A, B, C and DRB1 (CPT 81378) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81378-tissue-type-matching-detailed-a-b-c-and-drb1