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Procedure price report · Pathology

Tissue-type matching, basic, class II, each single locus

CPT 81376the billing code this page is about

Low-resolution HLA typing of one class II marker such as DRB1, DQB1 or DPB1; the price shown covers one locus, so several markers bill this code repeatedly.

Hospitals typically charge $228 cash for this outpatient procedure — the median across 1,789 hospitals that filed a usable cash price; the average of the middle 60% is $244. Most fall between $113 and $465 (20th–80th percentile).

Hospitals
1,789
States
50
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,789 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$64$127$228$392$697

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($64 vs $697).

How the prices are spread

$30 – $42: 29 hospitals$30$42 – $59: 50 hospitals$59 – $82: 83 hospitals$59$82 – $115: 111 hospitals$115 – $162: 252 hospitals$115$162 – $226: 274 hospitals$226 – $317: 301 hospitals$226$317 – $444: 226 hospitals$444 – $621: 167 hospitals$444$621 – $870: 118 hospitals$621median $228price bands are equal on a log scale
Hospitals per price band (1,611 of 1,789 — the bands cover the 5th to 95th percentile)
FromToHospitals
$30$4229
$42$5950
$59$8283
$82$115111
$115$162252
$162$226274
$226$317301
$317$444226
$444$621167
$621$870118

By state

The median cash price in each state, against the national median of $228.

Alaska: 7 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $284 across 20 hospitalsME$284Vermont: median $230 across 12 hospitalsVT$230New Hampshire: median $280 across 12 hospitalsNH$280Washington: median $268 across 39 hospitalsWA$268Idaho: 8 hospitals filed a usable price — fewer than 10, so no figureIDMontana: median $255 across 16 hospitalsMT$255North Dakota: median $413 across 19 hospitalsND$413Minnesota: median $244 across 72 hospitalsMN$244Illinois: median $317 across 84 hospitalsIL$317Wisconsin: median $403 across 88 hospitalsWI$403Michigan: median $169 across 66 hospitalsMI$169New York: median $228 across 72 hospitalsNY$228Massachusetts: median $501 across 42 hospitalsMA$501Oregon: median $237 across 34 hospitalsOR$237Nevada: 8 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: median $200 across 12 hospitalsWY$200South Dakota: median $298 across 12 hospitalsSD$298Iowa: median $178 across 50 hospitalsIA$178Indiana: median $195 across 53 hospitalsIN$195Ohio: median $236 across 94 hospitalsOH$236Pennsylvania: median $258 across 99 hospitalsPA$258New Jersey: median $134 across 49 hospitalsNJ$134Connecticut: median $519 across 13 hospitalsCT$519Rhode Island: 7 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $130 across 66 hospitalsCA$130Utah: 4 hospitals filed a usable price — fewer than 10, so no figureUTColorado: median $218 across 43 hospitalsCO$218Nebraska: median $326 across 21 hospitalsNE$326Missouri: median $262 across 44 hospitalsMO$262Kentucky: median $206 across 30 hospitalsKY$206West Virginia: median $29 across 23 hospitalsWV$29Virginia: median $250 across 37 hospitalsVA$250Maryland: median $84 across 24 hospitalsMD$84Delaware: 6 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $503 across 19 hospitalsAZ$503New Mexico: median $393 across 15 hospitalsNM$393Kansas: median $260 across 22 hospitalsKS$260Arkansas: median $104 across 19 hospitalsAR$104Tennessee: median $164 across 35 hospitalsTN$164North Carolina: median $185 across 38 hospitalsNC$185South Carolina: median $309 across 29 hospitalsSC$309Oklahoma: median $265 across 27 hospitalsOK$265Louisiana: median $133 across 26 hospitalsLA$133Mississippi: median $152 across 27 hospitalsMS$152Alabama: median $190 across 19 hospitalsAL$190Georgia: median $165 across 55 hospitalsGA$165Hawaii: median $161 across 10 hospitalsHI$161Texas: median $187 across 99 hospitalsTX$187Florida: median $66 across 63 hospitalsFL$66
Cash price by state, most expensive first. National median $228. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Connecticut CT13$519+127%$210 – $532
Arizona AZ19$503+120%$141 – $715
Massachusetts MA42$501+119%$354 – $719
North Dakota ND19$413+81%$180 – $864
Wisconsin WI88$403+76%$208 – $560
New Mexico NM15$393+72%$89 – $790
Nebraska NE21$326+43%$241 – $660
Illinois IL84$317+39%$146 – $489
South Carolina SC29$309+35%$233 – $338
South Dakota SD12$298+31%$33 – $554
Maine ME20$284+24%$82 – $318
New Hampshire NH12$280+23%$63 – $575
Washington WA39$268+17%$176 – $365
Oklahoma OK27$265+16%$183 – $338
Missouri MO44$262+15%$211 – $383
Kansas KS22$260+14%$168 – $484
Pennsylvania PA99$258+13%$122 – $857
Montana MT16$255+12%$98 – $380
Virginia VA37$250+9%$15 – $384
Minnesota MN72$244+7%$120 – $381
Oregon OR34$237+4%$144 – $309
Ohio OH94$236+3%$143 – $333
Vermont VT12$230+1%$158 – $300
New York NY72$2280%$122 – $532
Colorado CO43$218−4%$117 – $319
Kentucky KY30$206−10%$116 – $697
Wyoming WY12$200−12%$150 – $313
Indiana IN53$195−15%$162 – $259
Alabama AL19$190−17%$86 – $613
Texas TX99$187−18%$105 – $357
North Carolina NC38$185−19%$25 – $244
Iowa IA50$178−22%$128 – $453
Michigan MI66$169−26%$77 – $281
Georgia GA55$165−28%$161 – $450
Tennessee TN35$164−28%$108 – $214
Hawaii HI10$161−29%$161 – $531
Mississippi MS27$152−33%$86 – $246
New Jersey NJ49$134−41%$122 – $167
Louisiana LA26$133−42%$63 – $271
California CA66$130−43%$28 – $739
Arkansas AR19$104−54%$68 – $257
Maryland MD24$84−63%$60 – $168
Florida FL63$66−71%$53 – $285
West Virginia WV23$29−87%$29 – $339
Idaho ID8not enough hospitals filed a usable price
Nevada NV8not enough hospitals filed a usable price
Alaska AK7not enough hospitals filed a usable price
Rhode Island RI7not enough hospitals filed a usable price
Delaware DE6not enough hospitals filed a usable price
Utah UT4not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $228.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,323$208$104 – $457
Children’s43$276$86 – $661
Critical access418$274$155 – $475
Ownership
For-profit153$216$124 – $558
Government258$211$111 – $392
Non-profit1,373$235$109 – $475
System affiliation
Part of a system1,548$230$116 – $469
Independent241$216$109 – $421

Cash price vs list price

Median list price (chargemaster)$398
Median cash price$228
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,308 hospitals filed a usable inpatient cash price for this code. The median is $238 and the average of the middle 60% is $256; most fall between $119 and $480.

Cash price percentiles, inpatient, across 1,308 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$75$135$238$412$719

The most expensive tenth of hospitals charges at least 9.6× what the cheapest tenth charges ($75 vs $719).

Of the 1,416 hospitals that filed this code inpatient, 1,308 gave a usable cash price; 66 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 42 a list price only.

How complete is this

1,789 of the 3,956 hospitals with a price file in our corpus (45%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,924 hospitals that filed this code at all gave us
Usable cash price — counted1,789
Cash price carrying a plausibility flag — shown on the compare tool, excluded here81
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded53
Hospitals that filed this code1,924

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Hla Class II (Naag).

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Tissue-type matching, basic, class II, each single locus (CPT 81376) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81376-tissue-type-matching-basic-class-ii-each-single-locus