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Procedure price report · Pathology

Tissue-type matching, basic, class II DRB and DQB1

CPT 81375the billing code this page is about

Low-resolution HLA typing of the class II markers DRB1/3/4/5 and DQB1, used in transplant donor matching.

Hospitals typically charge $372 cash for this outpatient procedure — the median across 946 hospitals that filed a usable cash price; the average of the middle 60% is $401. Most fall between $198 and $798 (20th–80th percentile).

Hospitals
946
States
50
Filings dated
Nov 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 946 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$147$214$372$672$1,368

The most expensive tenth of hospitals charges at least 9.3× what the cheapest tenth charges ($147 vs $1,368).

How the prices are spread

$90 – $123: 25 hospitals$90$123 – $168: 56 hospitals$168 – $229: 172 hospitals$168$229 – $313: 103 hospitals$313 – $427: 122 hospitals$313$427 – $583: 144 hospitals$583 – $795: 87 hospitals$583$795 – $1,086: 78 hospitals$1,086 – $1,483: 27 hospitals$1,086$1,483 – $2,024: 44 hospitals$1,483median $372price bands are equal on a log scale
Hospitals per price band (858 of 946 — the bands cover the 5th to 95th percentile)
FromToHospitals
$90$12325
$123$16856
$168$229172
$229$313103
$313$427122
$427$583144
$583$79587
$795$1,08678
$1,086$1,48327
$1,483$2,02444

By state

The median cash price in each state, against the national median of $372.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $225 across 10 hospitalsME$225Vermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $355 across 26 hospitalsWA$355Idaho: 3 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 4 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 9 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $432 across 39 hospitalsMN$432Illinois: median $509 across 48 hospitalsIL$509Wisconsin: median $380 across 27 hospitalsWI$380Michigan: median $305 across 19 hospitalsMI$305New York: median $290 across 49 hospitalsNY$290Massachusetts: median $961 across 27 hospitalsMA$961Oregon: 8 hospitals filed a usable price — fewer than 10, so no figureORNevada: 5 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 2 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $212 across 16 hospitalsIA$212Indiana: median $382 across 31 hospitalsIN$382Ohio: median $223 across 46 hospitalsOH$223Pennsylvania: median $475 across 49 hospitalsPA$475New Jersey: median $243 across 34 hospitalsNJ$243Connecticut: 6 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 6 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $1,053 across 43 hospitalsCA$1,053Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: median $325 across 13 hospitalsCO$325Nebraska: 4 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $598 across 23 hospitalsMO$598Kentucky: median $513 across 16 hospitalsKY$513West Virginia: 7 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $208 across 28 hospitalsVA$208Maryland: median $527 across 19 hospitalsMD$527Delaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: median $1,397 across 16 hospitalsAZ$1,397New Mexico: 5 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 3 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 6 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $216 across 21 hospitalsTN$216North Carolina: median $191 across 36 hospitalsNC$191South Carolina: 3 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: median $473 across 14 hospitalsOK$473Louisiana: median $366 across 17 hospitalsLA$366Mississippi: median $221 across 13 hospitalsMS$221Alabama: 6 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $372 across 46 hospitalsGA$372Hawaii: 4 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $483 across 74 hospitalsTX$483Florida: median $160 across 49 hospitalsFL$160
Cash price by state, most expensive first. National median $372. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Arizona AZ16$1,397+276%$355 – $1,515
California CA43$1,053+183%$200 – $2,464
Massachusetts MA27$961+158%$390 – $1,368
Missouri MO23$598+61%$332 – $1,054
Maryland MD19$527+42%$356 – $760
Kentucky KY16$513+38%$264 – $970
Illinois IL48$509+37%$285 – $883
Texas TX74$483+30%$445 – $1,559
Pennsylvania PA49$475+28%$171 – $1,025
Oklahoma OK14$473+27%$189 – $726
Minnesota MN39$432+16%$347 – $517
Indiana IN31$382+3%$237 – $468
Wisconsin WI27$380+2%$245 – $437
Georgia GA46$3720%$214 – $1,015
Louisiana LA17$366−2%$283 – $510
Washington WA26$355−5%$252 – $844
Colorado CO13$325−13%$193 – $466
Michigan MI19$305−18%$231 – $648
New York NY49$290−22%$200 – $612
New Jersey NJ34$243−35%$221 – $806
Maine ME10$225−40%$139 – $325
Ohio OH46$223−40%$194 – $395
Mississippi MS13$221−41%$150 – $420
Tennessee TN21$216−42%$111 – $387
Iowa IA16$212−43%$212 – $212
Virginia VA28$208−44%$194 – $475
North Carolina NC36$191−49%$90 – $198
Florida FL49$160−57%$128 – $973
North Dakota ND9not enough hospitals filed a usable price
Oregon OR8not enough hospitals filed a usable price
West Virginia WV7not enough hospitals filed a usable price
Alabama AL6not enough hospitals filed a usable price
Arkansas AR6not enough hospitals filed a usable price
Connecticut CT6not enough hospitals filed a usable price
Rhode Island RI6not enough hospitals filed a usable price
New Mexico NM5not enough hospitals filed a usable price
Nevada NV5not enough hospitals filed a usable price
South Dakota SD5not enough hospitals filed a usable price
Hawaii HI4not enough hospitals filed a usable price
Montana MT4not enough hospitals filed a usable price
Nebraska NE4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Idaho ID3not enough hospitals filed a usable price
Kansas KS3not enough hospitals filed a usable price
South Carolina SC3not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
Wyoming WY2not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $372.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care789$372$198 – $800
Children’s24$396$225 – $1,725
Critical access129$382$210 – $700
Ownership
For-profit103$483$216 – $1,112
Government119$269$174 – $649
Non-profit720$380$200 – $799
System affiliation
Part of a system839$372$198 – $800
Independent107$375$220 – $669

Cash price vs list price

Median list price (chargemaster)$744
Median cash price$372
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

659 hospitals filed a usable inpatient cash price for this code. The median is $382 and the average of the middle 60% is $408; most fall between $199 and $797.

Cash price percentiles, inpatient, across 659 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$156$213$382$668$1,551

The most expensive tenth of hospitals charges at least 10.0× what the cheapest tenth charges ($156 vs $1,551).

Of the 700 hospitals that filed this code inpatient, 659 gave a usable cash price; 31 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 10 a list price only.

How complete is this

946 of the 3,956 hospitals with a price file in our corpus (24%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 983 hospitals that filed this code at all gave us
Usable cash price — counted946
Cash price carrying a plausibility flag — shown on the compare tool, excluded here27
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded10
Hospitals that filed this code983

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HLA II TYPING AG EQUIV LR.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Tissue-type matching, basic, class II DRB and DQB1 (CPT 81375) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81375-tissue-type-matching-basic-class-ii-drb-and-dqb1