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Procedure price report · Pathology

Beta globin gene test, full gene sequence

CPT 81364the billing code this page is about

Genetic test that reads the complete coding sequence of the HBB (beta globin) gene to identify variants linked to sickle cell disease, thalassemia and related hemoglobin conditions.

Hospitals typically charge $612 cash for this outpatient procedure — the median across 1,254 hospitals that filed a usable cash price; the average of the middle 60% is $611. Most fall between $357 and $1,044 (20th–80th percentile).

Hospitals
1,254
States
50
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,254 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$281$380$612$913$1,413

The most expensive tenth of hospitals charges at least 5.0× what the cheapest tenth charges ($281 vs $1,413).

How the prices are spread

$200 – $249: 33 hospitals$200$249 – $310: 64 hospitals$310 – $386: 174 hospitals$310$386 – $480: 162 hospitals$480 – $597: 129 hospitals$480$597 – $744: 192 hospitals$744 – $926: 144 hospitals$744$926 – $1,152: 107 hospitals$1,152 – $1,434: 73 hospitals$1,152$1,434 – $1,785: 54 hospitals$1,434median $612price bands are equal on a log scale
Hospitals per price band (1,132 of 1,254 — the bands cover the 5th to 95th percentile)
FromToHospitals
$200$24933
$249$31064
$310$386174
$386$480162
$480$597129
$597$744192
$744$926144
$926$1,152107
$1,152$1,43473
$1,434$1,78554

By state

The median cash price in each state, against the national median of $612.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 4 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $327 across 11 hospitalsNH$327Washington: median $519 across 32 hospitalsWA$519Idaho: 3 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 3 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 8 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $440 across 44 hospitalsMN$440Illinois: median $682 across 52 hospitalsIL$682Wisconsin: median $673 across 70 hospitalsWI$673Michigan: median $705 across 34 hospitalsMI$705New York: median $570 across 51 hospitalsNY$570Massachusetts: median $852 across 24 hospitalsMA$852Oregon: median $390 across 16 hospitalsOR$390Nevada: 6 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 3 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 6 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $312 across 25 hospitalsIA$312Indiana: median $510 across 37 hospitalsIN$510Ohio: median $627 across 71 hospitalsOH$627Pennsylvania: median $808 across 65 hospitalsPA$808New Jersey: median $357 across 44 hospitalsNJ$357Connecticut: median $1,266 across 10 hospitalsCT$1,266Rhode Island: 5 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $745 across 38 hospitalsCA$745Utah: median $560 across 25 hospitalsUT$560Colorado: median $421 across 25 hospitalsCO$421Nebraska: 1 hospital filed a usable price — fewer than 10, so no figureNEMissouri: median $528 across 38 hospitalsMO$528Kentucky: median $672 across 30 hospitalsKY$672West Virginia: median $707 across 23 hospitalsWV$707Virginia: median $447 across 48 hospitalsVA$447Maryland: median $666 across 19 hospitalsMD$666Delaware: 4 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $496 across 14 hospitalsAZ$496New Mexico: 3 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $1,200 across 13 hospitalsKS$1,200Arkansas: median $425 across 17 hospitalsAR$425Tennessee: median $281 across 28 hospitalsTN$281North Carolina: median $614 across 58 hospitalsNC$614South Carolina: median $815 across 25 hospitalsSC$815Oklahoma: median $593 across 23 hospitalsOK$593Louisiana: median $384 across 24 hospitalsLA$384Mississippi: median $189 across 13 hospitalsMS$189Alabama: 8 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $461 across 46 hospitalsGA$461Hawaii: 5 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $675 across 60 hospitalsTX$675Florida: median $497 across 37 hospitalsFL$497
Cash price by state, most expensive first. National median $612. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Connecticut CT10$1,266+107%$671 – $1,414
Kansas KS13$1,200+96%$652 – $2,745
Massachusetts MA24$852+39%$544 – $1,218
South Carolina SC25$815+33%$628 – $1,023
Pennsylvania PA65$808+32%$393 – $2,081
California CA38$745+22%$565 – $745
West Virginia WV23$707+16%$475 – $748
Michigan MI34$705+15%$448 – $799
Illinois IL52$682+11%$466 – $863
Texas TX60$675+10%$406 – $1,047
Wisconsin WI70$673+10%$451 – $1,070
Kentucky KY30$672+10%$365 – $1,784
Maryland MD19$666+9%$408 – $1,748
Ohio OH71$627+2%$400 – $1,456
North Carolina NC58$6140%$355 – $730
Oklahoma OK23$593−3%$446 – $1,413
New York NY51$570−7%$325 – $1,013
Utah UT25$560−8%$560 – $659
Missouri MO38$528−14%$437 – $663
Washington WA32$519−15%$358 – $1,224
Indiana IN37$510−17%$405 – $736
Florida FL37$497−19%$293 – $1,049
Arizona AZ14$496−19%$323 – $1,565
Georgia GA46$461−25%$362 – $1,026
Virginia VA48$447−27%$120 – $913
Minnesota MN44$440−28%$89 – $691
Arkansas AR17$425−31%$236 – $666
Colorado CO25$421−31%$325 – $783
Oregon OR16$390−36%$343 – $987
Louisiana LA24$384−37%$152 – $974
New Jersey NJ44$357−42%$325 – $808
New Hampshire NH11$327−47%$186 – $939
Iowa IA25$312−49%$312 – $1,023
Tennessee TN28$281−54%$236 – $422
Mississippi MS13$189−69%$150 – $205
Alabama AL8not enough hospitals filed a usable price
North Dakota ND8not enough hospitals filed a usable price
Nevada NV6not enough hospitals filed a usable price
South Dakota SD6not enough hospitals filed a usable price
Hawaii HI5not enough hospitals filed a usable price
Rhode Island RI5not enough hospitals filed a usable price
Delaware DE4not enough hospitals filed a usable price
Maine ME4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Idaho ID3not enough hospitals filed a usable price
Montana MT3not enough hospitals filed a usable price
New Mexico NM3not enough hospitals filed a usable price
Wyoming WY3not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
Nebraska NE1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $612.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,027$614$355 – $1,043
Children’s31$652$364 – $869
Critical access189$560$375 – $1,062
Ownership
For-profit95$622$390 – $1,047
Government170$588$325 – $804
Non-profit982$606$357 – $1,047
System affiliation
Part of a system1,106$593$357 – $1,047
Independent148$621$364 – $1,013

Cash price vs list price

Median list price (chargemaster)$1,080
Median cash price$612
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

932 hospitals filed a usable inpatient cash price for this code. The median is $633 and the average of the middle 60% is $649; most fall between $369 and $1,066.

Cash price percentiles, inpatient, across 932 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$281$400$633$979$1,428

The most expensive tenth of hospitals charges at least 5.1× what the cheapest tenth charges ($281 vs $1,428).

Of the 1,037 hospitals that filed this code inpatient, 932 gave a usable cash price; 58 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 47 a list price only.

How complete is this

1,254 of the 3,956 hospitals with a price file in our corpus (32%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,388 hospitals that filed this code at all gave us
Usable cash price — counted1,254
Cash price carrying a plausibility flag — shown on the compare tool, excluded here78
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded54
Hospitals that filed this code1,388

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HBB FULL GENE SEQUENCE.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Beta globin gene test, full gene sequence (CPT 81364) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81364-beta-globin-gene-test-full-gene-sequence