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Procedure price report · Pathology

TP53 gene test of hot spot regions only

CPT 81352the billing code this page is about

Laboratory test that reads only the selected hot spot regions of the TP53 gene where mutations most often occur, rather than the whole gene.

Hospitals typically charge $669 cash for this outpatient procedure — the median across 1,022 hospitals that filed a usable cash price; the average of the middle 60% is $703. Most fall between $380 and $1,135 (20th–80th percentile).

Hospitals
1,022
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,022 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$316$423$669$1,043$1,534

The most expensive tenth of hospitals charges at least 4.8× what the cheapest tenth charges ($316 vs $1,534).

How the prices are spread

$241 – $296: 41 hospitals$241$296 – $363: 91 hospitals$363 – $447: 88 hospitals$363$447 – $549: 108 hospitals$549 – $674: 136 hospitals$549$674 – $828: 135 hospitals$828 – $1,017: 109 hospitals$828$1,017 – $1,250: 82 hospitals$1,250 – $1,536: 87 hospitals$1,250$1,536 – $1,887: 44 hospitals$1,536median $669price bands are equal on a log scale
Hospitals per price band (921 of 1,022 — the bands cover the 5th to 95th percentile)
FromToHospitals
$241$29641
$296$36391
$363$44788
$447$549108
$549$674136
$674$828135
$828$1,017109
$1,017$1,25082
$1,250$1,53687
$1,536$1,88744

By state

The median cash price in each state, against the national median of $669.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: median $384 across 13 hospitalsME$384Vermont: 4 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 6 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $468 across 10 hospitalsWA$468Idaho: 9 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $603 across 54 hospitalsMN$603Illinois: median $884 across 41 hospitalsIL$884Wisconsin: median $870 across 75 hospitalsWI$870Michigan: median $509 across 45 hospitalsMI$509New York: median $578 across 37 hospitalsNY$578Massachusetts: median $890 across 17 hospitalsMA$890Oregon: median $1,221 across 15 hospitalsOR$1,221Nevada: 6 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: 9 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $316 across 20 hospitalsIA$316Indiana: median $464 across 32 hospitalsIN$464Ohio: median $1,135 across 52 hospitalsOH$1,135Pennsylvania: median $379 across 34 hospitalsPA$379New Jersey: median $362 across 33 hospitalsNJ$362Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $554 across 27 hospitalsCA$554Utah: median $569 across 24 hospitalsUT$569Colorado: median $563 across 10 hospitalsCO$563Nebraska: 6 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $983 across 19 hospitalsMO$983Kentucky: median $1,246 across 16 hospitalsKY$1,246West Virginia: median $871 across 14 hospitalsWV$871Virginia: median $485 across 46 hospitalsVA$485Maryland: median $1,111 across 15 hospitalsMD$1,111Delaware: 4 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 7 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 6 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 5 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: median $214 across 10 hospitalsAR$214Tennessee: median $423 across 25 hospitalsTN$423North Carolina: median $473 across 41 hospitalsNC$473South Carolina: median $1,448 across 24 hospitalsSC$1,448Oklahoma: median $706 across 18 hospitalsOK$706Louisiana: median $249 across 16 hospitalsLA$249Mississippi: median $310 across 13 hospitalsMS$310Alabama: 8 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $841 across 41 hospitalsGA$841Hawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $787 across 72 hospitalsTX$787Florida: median $529 across 28 hospitalsFL$529
Cash price by state, most expensive first. National median $669. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Carolina SC24$1,448+116%$813 – $1,534
Kentucky KY16$1,246+86%$989 – $1,617
Oregon OR15$1,221+82%$500 – $1,392
Ohio OH52$1,135+70%$598 – $1,478
Maryland MD15$1,111+66%$816 – $1,239
Missouri MO19$983+47%$495 – $1,082
Massachusetts MA17$890+33%$737 – $1,872
Illinois IL41$884+32%$762 – $1,095
West Virginia WV14$871+30%$578 – $1,501
Wisconsin WI75$870+30%$636 – $1,095
Georgia GA41$841+26%$807 – $1,335
Texas TX72$787+18%$344 – $980
Oklahoma OK18$706+5%$275 – $1,977
Minnesota MN54$603−10%$466 – $919
New York NY37$578−14%$330 – $988
Utah UT24$569−15%$569 – $669
Colorado CO10$563−16%$427 – $2,523
California CA27$554−17%$554 – $574
Florida FL28$529−21%$227 – $737
Michigan MI45$509−24%$420 – $738
Virginia VA46$485−28%$355 – $833
North Carolina NC41$473−29%$380 – $822
Washington WA10$468−30%$468 – $612
Indiana IN32$464−31%$372 – $774
Tennessee TN25$423−37%$257 – $533
Maine ME13$384−43%$208 – $902
Pennsylvania PA34$379−43%$54 – $911
New Jersey NJ33$362−46%$330 – $2,915
Iowa IA20$316−53%$316 – $724
Mississippi MS13$310−54%$246 – $482
Louisiana LA16$249−63%$172 – $694
Arkansas AR10$214−68%$170 – $713
Idaho ID9not enough hospitals filed a usable price
South Dakota SD9not enough hospitals filed a usable price
Alabama AL8not enough hospitals filed a usable price
Arizona AZ7not enough hospitals filed a usable price
Nebraska NE6not enough hospitals filed a usable price
New Hampshire NH6not enough hospitals filed a usable price
New Mexico NM6not enough hospitals filed a usable price
Nevada NV6not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Kansas KS5not enough hospitals filed a usable price
North Dakota ND5not enough hospitals filed a usable price
Delaware DE4not enough hospitals filed a usable price
Vermont VT4not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $669.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care848$677$374 – $1,095
Children’s7fewer than 20 hospitals
Critical access161$649$447 – $1,427
Ownership
For-profit76$787$497 – $1,246
Government120$533$344 – $868
Non-profit820$681$380 – $1,166
System affiliation
Part of a system938$669$380 – $1,135
Independent84$737$379 – $1,054

Cash price vs list price

Median list price (chargemaster)$1,219
Median cash price$669
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

781 hospitals filed a usable inpatient cash price for this code. The median is $737 and the average of the middle 60% is $728; most fall between $418 and $1,135.

Cash price percentiles, inpatient, across 781 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$316$473$737$1,082$1,524

The most expensive tenth of hospitals charges at least 4.8× what the cheapest tenth charges ($316 vs $1,524).

Of the 840 hospitals that filed this code inpatient, 781 gave a usable cash price; 36 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 23 a list price only.

How complete is this

1,022 of the 3,956 hospitals with a price file in our corpus (26%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,099 hospitals that filed this code at all gave us
Usable cash price — counted1,022
Cash price carrying a plausibility flag — shown on the compare tool, excluded here52
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded25
Hospitals that filed this code1,099

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Tp53 Ngs.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “TP53 gene test of hot spot regions only (CPT 81352) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81352-tp53-gene-test-of-hot-spot-regions-only