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Procedure price report · Pathology

MPL gene sequencing of one region

CPT 81339the billing code this page is about

Laboratory test that reads the DNA sequence of a single region (exon 10) of the MPL gene to find mutations linked to bone marrow disorders.

Hospitals typically charge $321 cash for this outpatient procedure — the median across 1,280 hospitals that filed a usable cash price; the average of the middle 60% is $355. Most fall between $190 and $607 (20th–80th percentile).

Hospitals
1,280
States
49
Filings dated
Jun 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,280 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$121$222$321$546$770

The most expensive tenth of hospitals charges at least 6.4× what the cheapest tenth charges ($121 vs $770).

How the prices are spread

$92 – $117: 46 hospitals$92$117 – $149: 68 hospitals$149 – $190: 77 hospitals$149$190 – $242: 122 hospitals$242 – $307: 186 hospitals$242$307 – $391: 203 hospitals$391 – $498: 121 hospitals$391$498 – $634: 155 hospitals$634 – $807: 126 hospitals$634$807 – $1,028: 49 hospitals$807median $321price bands are equal on a log scale
Hospitals per price band (1,153 of 1,280 — the bands cover the 5th to 95th percentile)
FromToHospitals
$92$11746
$117$14968
$149$19077
$190$242122
$242$307186
$307$391203
$391$498121
$498$634155
$634$807126
$807$1,02849

By state

The median cash price in each state, against the national median of $321.

Alaska: 4 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $176 across 17 hospitalsME$176Vermont: 8 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 6 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $286 across 16 hospitalsWA$286Idaho: 8 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 9 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $519 across 12 hospitalsND$519Minnesota: median $346 across 44 hospitalsMN$346Illinois: median $421 across 56 hospitalsIL$421Wisconsin: median $343 across 41 hospitalsWI$343Michigan: median $256 across 38 hospitalsMI$256New York: median $325 across 52 hospitalsNY$325Massachusetts: median $495 across 29 hospitalsMA$495Oregon: median $464 across 23 hospitalsOR$464Nevada: 7 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 5 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 6 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $361 across 38 hospitalsIA$361Indiana: median $246 across 41 hospitalsIN$246Ohio: median $536 across 67 hospitalsOH$536Pennsylvania: median $513 across 75 hospitalsPA$513New Jersey: median $204 across 31 hospitalsNJ$204Connecticut: median $541 across 10 hospitalsCT$541Rhode Island: 5 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $314 across 37 hospitalsCA$314Utah: no hospital in the corpus filed a usable priceUTColorado: median $316 across 25 hospitalsCO$316Nebraska: median $445 across 19 hospitalsNE$445Missouri: median $392 across 46 hospitalsMO$392Kentucky: median $428 across 23 hospitalsKY$428West Virginia: median $163 across 17 hospitalsWV$163Virginia: median $253 across 41 hospitalsVA$253Maryland: median $300 across 13 hospitalsMD$300Delaware: 5 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $272 across 10 hospitalsAZ$272New Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: median $316 across 20 hospitalsKS$316Arkansas: median $123 across 21 hospitalsAR$123Tennessee: median $225 across 35 hospitalsTN$225North Carolina: median $272 across 34 hospitalsNC$272South Carolina: median $286 across 25 hospitalsSC$286Oklahoma: median $227 across 24 hospitalsOK$227Louisiana: median $260 across 25 hospitalsLA$260Mississippi: 9 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 9 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $314 across 49 hospitalsGA$314Hawaii: 4 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $455 across 79 hospitalsTX$455Florida: median $320 across 61 hospitalsFL$320
Cash price by state, most expensive first. National median $321. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Connecticut CT10$541+68%$356 – $578
Ohio OH67$536+67%$302 – $831
North Dakota ND12$519+61%$370 – $876
Pennsylvania PA75$513+60%$261 – $1,522
Massachusetts MA29$495+54%$291 – $771
Oregon OR23$464+44%$301 – $642
Texas TX79$455+42%$151 – $735
Nebraska NE19$445+39%$187 – $689
Kentucky KY23$428+33%$219 – $2,121
Illinois IL56$421+31%$237 – $712
Missouri MO46$392+22%$202 – $503
Iowa IA38$361+12%$178 – $557
Minnesota MN44$346+8%$39 – $452
Wisconsin WI41$343+7%$343 – $725
New York NY52$325+1%$185 – $500
Florida FL61$3200%$223 – $648
Colorado CO25$316−2%$261 – $593
Kansas KS20$316−2%$148 – $451
California CA37$314−2%$208 – $314
Georgia GA49$314−2%$247 – $639
Maryland MD13$300−7%$268 – $443
South Carolina SC25$286−11%$286 – $404
Washington WA16$286−11%$271 – $344
Arizona AZ10$272−15%$218 – $636
North Carolina NC34$272−15%$161 – $417
Louisiana LA25$260−19%$144 – $412
Michigan MI38$256−20%$107 – $310
Virginia VA41$253−21%$121 – $613
Indiana IN41$246−23%$133 – $334
Oklahoma OK24$227−29%$99 – $541
Tennessee TN35$225−30%$121 – $248
New Jersey NJ31$204−37%$185 – $518
Maine ME17$176−45%$79 – $354
West Virginia WV17$163−49%$140 – $336
Arkansas AR21$123−62%$120 – $433
Alabama AL9not enough hospitals filed a usable price
Mississippi MS9not enough hospitals filed a usable price
Montana MT9not enough hospitals filed a usable price
Idaho ID8not enough hospitals filed a usable price
Vermont VT8not enough hospitals filed a usable price
Nevada NV7not enough hospitals filed a usable price
New Hampshire NH6not enough hospitals filed a usable price
South Dakota SD6not enough hospitals filed a usable price
Delaware DE5not enough hospitals filed a usable price
Rhode Island RI5not enough hospitals filed a usable price
Wyoming WY5not enough hospitals filed a usable price
Alaska AK4not enough hospitals filed a usable price
Hawaii HI4not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $321.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care992$314$185 – $606
Children’s18fewer than 20 hospitals
Critical access264$391$247 – $642
Ownership
For-profit94$314$206 – $639
Government169$301$185 – $545
Non-profit1,011$334$194 – $613
System affiliation
Part of a system1,118$324$187 – $623
Independent162$299$202 – $556

Cash price vs list price

Median list price (chargemaster)$596
Median cash price$321
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

918 hospitals filed a usable inpatient cash price for this code. The median is $335 and the average of the middle 60% is $380; most fall between $203 and $648.

Cash price percentiles, inpatient, across 918 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$121$230$335$597$830

The most expensive tenth of hospitals charges at least 6.9× what the cheapest tenth charges ($121 vs $830).

Of the 1,033 hospitals that filed this code inpatient, 918 gave a usable cash price; 70 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 45 a list price only.

How complete is this

1,280 of the 3,956 hospitals with a price file in our corpus (32%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,420 hospitals that filed this code at all gave us
Usable cash price — counted1,280
Cash price carrying a plausibility flag — shown on the compare tool, excluded here80
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded2
A list price only, no cash figure — excluded58
Hospitals that filed this code1,420

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Mpl Ngs.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MPL gene sequencing of one region (CPT 81339) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81339-mpl-gene-sequencing-of-one-region