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Procedure price report · Pathology

MPL gene test for common blood cancer mutations

CPT 81338the billing code this page is about

Laboratory test that checks the MPL gene for the few mutations most often seen in bone marrow disorders such as essential thrombocythemia and myelofibrosis.

Hospitals typically charge $337 cash for this outpatient procedure — the median across 1,307 hospitals that filed a usable cash price; the average of the middle 60% is $363. Most fall between $169 and $654 (20th–80th percentile).

Hospitals
1,307
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,307 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$119$194$337$576$898

The most expensive tenth of hospitals charges at least 7.5× what the cheapest tenth charges ($119 vs $898).

How the prices are spread

$95 – $122: 75 hospitals$95$122 – $158: 85 hospitals$158 – $204: 121 hospitals$158$204 – $263: 154 hospitals$263 – $339: 166 hospitals$263$339 – $437: 140 hospitals$437 – $564: 154 hospitals$437$564 – $727: 150 hospitals$727 – $938: 76 hospitals$727$938 – $1,210: 56 hospitals$938median $337price bands are equal on a log scale
Hospitals per price band (1,177 of 1,307 — the bands cover the 5th to 95th percentile)
FromToHospitals
$95$12275
$122$15885
$158$204121
$204$263154
$263$339166
$339$437140
$437$564154
$564$727150
$727$93876
$938$1,21056

By state

The median cash price in each state, against the national median of $337.

Alaska: 4 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 3 hospitals filed a usable price — fewer than 10, so no figureMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: median $453 across 11 hospitalsNH$453Washington: median $254 across 39 hospitalsWA$254Idaho: 9 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 3 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureNDMinnesota: median $289 across 30 hospitalsMN$289Illinois: median $399 across 63 hospitalsIL$399Wisconsin: median $712 across 58 hospitalsWI$712Michigan: median $225 across 49 hospitalsMI$225New York: median $253 across 47 hospitalsNY$253Massachusetts: median $467 across 22 hospitalsMA$467Oregon: median $324 across 18 hospitalsOR$324Nevada: 8 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 3 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 7 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $154 across 16 hospitalsIA$154Indiana: median $277 across 52 hospitalsIN$277Ohio: median $557 across 52 hospitalsOH$557Pennsylvania: median $1,170 across 52 hospitalsPA$1,170New Jersey: median $165 across 41 hospitalsNJ$165Connecticut: median $424 across 11 hospitalsCT$424Rhode Island: 4 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $253 across 39 hospitalsCA$253Utah: median $849 across 30 hospitalsUT$849Colorado: median $435 across 29 hospitalsCO$435Nebraska: median $361 across 12 hospitalsNE$361Missouri: median $454 across 18 hospitalsMO$454Kentucky: median $442 across 36 hospitalsKY$442West Virginia: median $388 across 27 hospitalsWV$388Virginia: median $270 across 50 hospitalsVA$270Maryland: median $383 across 22 hospitalsMD$383Delaware: 3 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $253 across 15 hospitalsAZ$253New Mexico: median $278 across 13 hospitalsNM$278Kansas: median $563 across 17 hospitalsKS$563Arkansas: 5 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $193 across 26 hospitalsTN$193North Carolina: median $245 across 39 hospitalsNC$245South Carolina: median $451 across 32 hospitalsSC$451Oklahoma: median $186 across 32 hospitalsOK$186Louisiana: median $326 across 17 hospitalsLA$326Mississippi: median $122 across 11 hospitalsMS$122Alabama: 8 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $251 across 57 hospitalsGA$251Hawaii: median $332 across 11 hospitalsHI$332Texas: median $287 across 94 hospitalsTX$287Florida: median $393 across 61 hospitalsFL$393
Cash price by state, most expensive first. National median $337. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Pennsylvania PA52$1,170+247%$150 – $1,234
Utah UT30$849+152%$399 – $999
Wisconsin WI58$712+111%$326 – $1,210
Kansas KS17$563+67%$177 – $1,278
Ohio OH52$557+65%$241 – $674
Massachusetts MA22$467+39%$302 – $625
Missouri MO18$454+35%$260 – $563
New Hampshire NH11$453+34%$215 – $680
South Carolina SC32$451+34%$287 – $460
Kentucky KY36$442+31%$183 – $746
Colorado CO29$435+29%$305 – $675
Connecticut CT11$424+26%$275 – $469
Illinois IL63$399+18%$160 – $631
Florida FL61$393+17%$259 – $664
West Virginia WV27$388+15%$388 – $566
Maryland MD22$383+14%$280 – $546
Nebraska NE12$361+7%$337 – $766
Hawaii HI11$332−2%$143 – $335
Louisiana LA17$326−3%$112 – $568
Oregon OR18$324−4%$282 – $386
Minnesota MN30$289−14%$60 – $306
Texas TX94$287−15%$115 – $754
New Mexico NM13$278−17%$195 – $509
Indiana IN52$277−18%$205 – $451
Virginia VA50$270−20%$193 – $444
Washington WA39$254−25%$90 – $438
Arizona AZ15$253−25%$114 – $601
New York NY47$253−25%$150 – $573
California CA39$253−25%$250 – $337
Georgia GA57$251−26%$119 – $536
North Carolina NC39$245−27%$164 – $613
Michigan MI49$225−33%$138 – $621
Tennessee TN26$193−43%$175 – $214
Oklahoma OK32$186−45%$99 – $470
New Jersey NJ41$165−51%$150 – $173
Iowa IA16$154−54%$154 – $374
Mississippi MS11$122−64%$107 – $230
Idaho ID9not enough hospitals filed a usable price
Alabama AL8not enough hospitals filed a usable price
Nevada NV8not enough hospitals filed a usable price
South Dakota SD7not enough hospitals filed a usable price
Arkansas AR5not enough hospitals filed a usable price
Alaska AK4not enough hospitals filed a usable price
Rhode Island RI4not enough hospitals filed a usable price
Delaware DE3not enough hospitals filed a usable price
Maine ME3not enough hospitals filed a usable price
Montana MT3not enough hospitals filed a usable price
Wyoming WY3not enough hospitals filed a usable price
North Dakota ND1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $337.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,077$324$164 – $640
Children’s13fewer than 20 hospitals
Critical access209$400$225 – $704
Ownership
For-profit143$322$173 – $746
Government160$345$175 – $565
Non-profit996$337$165 – $672
System affiliation
Part of a system1,156$332$165 – $654
Independent151$371$213 – $677

Cash price vs list price

Median list price (chargemaster)$621
Median cash price$337
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

941 hospitals filed a usable inpatient cash price for this code. The median is $340 and the average of the middle 60% is $390; most fall between $180 and $674.

Cash price percentiles, inpatient, across 941 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$118$214$340$621$946

The most expensive tenth of hospitals charges at least 8.0× what the cheapest tenth charges ($118 vs $946).

Of the 1,034 hospitals that filed this code inpatient, 941 gave a usable cash price; 44 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 49 a list price only.

How complete is this

1,307 of the 3,956 hospitals with a price file in our corpus (33%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,418 hospitals that filed this code at all gave us
Usable cash price — counted1,307
Cash price carrying a plausibility flag — shown on the compare tool, excluded here64
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded45
Hospitals that filed this code1,418

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MPL GENE COMMON VARIANTS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MPL gene test for common blood cancer mutations (CPT 81338) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81338-mpl-gene-test-for-common-blood-cancer-mutations