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Procedure price report · Pathology

Full gene sequencing of the SMN1 gene

CPT 81336the billing code this page is about

Laboratory test that reads the entire coding sequence of the SMN1 gene, the gene involved in spinal muscular atrophy.

Hospitals typically charge $651 cash for this outpatient procedure — the median across 282 hospitals that filed a usable cash price; the average of the middle 60% is $706. Most fall between $301 and $1,200 (20th–80th percentile).

Hospitals
282
States
35
Filings dated
Oct 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 282 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$237$331$651$1,138$1,232

The most expensive tenth of hospitals charges at least 5.2× what the cheapest tenth charges ($237 vs $1,232).

How the prices are spread

$232 – $279: 18 hospitals$232$279 – $334: 48 hospitals$334 – $401: 16 hospitals$334$401 – $480: 16 hospitals$480 – $576: 25 hospitals$480$576 – $691: 26 hospitals$691 – $828: 7 hospitals$691$828 – $993: 39 hospitals$993 – $1,191: 17 hospitals$993$1,191 – $1,428: 44 hospitals$1,191median $651price bands are equal on a log scale
Hospitals per price band (256 of 282 — the bands cover the 5th to 95th percentile)
FromToHospitals
$232$27918
$279$33448
$334$40116
$401$48016
$480$57625
$576$69126
$691$8287
$828$99339
$993$1,19117
$1,191$1,42844

By state

The median cash price in each state, against the national median of $651.

Alaska: no hospital in the corpus filed a usable priceAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: 4 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $880 across 11 hospitalsMN$880Illinois: 6 hospitals filed a usable price — fewer than 10, so no figureILWisconsin: 8 hospitals filed a usable price — fewer than 10, so no figureWIMichigan: 4 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $301 across 17 hospitalsNY$301Massachusetts: 6 hospitals filed a usable price — fewer than 10, so no figureMAOregon: no hospital in the corpus filed a usable priceORNevada: 1 hospital filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $289 across 13 hospitalsIA$289Indiana: median $367 across 13 hospitalsIN$367Ohio: median $1,253 across 19 hospitalsOH$1,253Pennsylvania: median $57 across 11 hospitalsPA$57New Jersey: median $331 across 23 hospitalsNJ$331Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $689 across 19 hospitalsCA$689Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: 2 hospitals filed a usable price — fewer than 10, so no figureCONebraska: no hospital in the corpus filed a usable priceNEMissouri: 2 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 7 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: 2 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $522 across 19 hospitalsVA$522Maryland: no hospital in the corpus filed a usable priceMDDelaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 2 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: no hospital in the corpus filed a usable priceARTennessee: median $237 across 13 hospitalsTN$237North Carolina: no hospital in the corpus filed a usable priceNCSouth Carolina: median $1,138 across 11 hospitalsSC$1,138Oklahoma: 6 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 2 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 7 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: 9 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $1,200 across 33 hospitalsTX$1,200Florida: 2 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $651. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Ohio OH19$1,253+93%$1,174 – $1,684
Texas TX33$1,200+84%$1,200 – $1,200
South Carolina SC11$1,138+75%$1,138 – $1,138
Minnesota MN11$880+35%$750 – $880
California CA19$689+6%$689 – $689
Virginia VA19$522−20%$237 – $860
Indiana IN13$367−44%$321 – $518
New Jersey NJ23$331−49%$301 – $331
New York NY17$301−54%$301 – $362
Iowa IA13$289−56%$289 – $289
Tennessee TN13$237−64%$232 – $237
Pennsylvania PA11$57−91%$52 – $70
Georgia GA9not enough hospitals filed a usable price
Wisconsin WI8not enough hospitals filed a usable price
Kentucky KY7not enough hospitals filed a usable price
Mississippi MS7not enough hospitals filed a usable price
Illinois IL6not enough hospitals filed a usable price
Massachusetts MA6not enough hospitals filed a usable price
Oklahoma OK6not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Michigan MI4not enough hospitals filed a usable price
Washington WA4not enough hospitals filed a usable price
Arizona AZ2not enough hospitals filed a usable price
Colorado CO2not enough hospitals filed a usable price
Florida FL2not enough hospitals filed a usable price
Louisiana LA2not enough hospitals filed a usable price
Missouri MO2not enough hospitals filed a usable price
West Virginia WV2not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
Nevada NV1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $651.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care234$670$301 – $1,200
Children’s9fewer than 20 hospitals
Critical access37$522$381 – $900
Ownership
For-profit16fewer than 20 hospitals
Government28$419$301 – $569
Non-profit236$689$301 – $1,138
System affiliation
Part of a system266$659$301 – $1,200
Independent16fewer than 20 hospitals

Cash price vs list price

Median list price (chargemaster)$1,271
Median cash price$651
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

197 hospitals filed a usable inpatient cash price for this code. The median is $781 and the average of the middle 60% is $845; most fall between $362 and $1,200.

Cash price percentiles, inpatient, across 197 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$237$474$781$1,200$1,265

The most expensive tenth of hospitals charges at least 5.3× what the cheapest tenth charges ($237 vs $1,265).

Of the 201 hospitals that filed this code inpatient, 197 gave a usable cash price; 2 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 2 a list price only.

How complete is this

282 of the 3,956 hospitals with a price file in our corpus (7%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 289 hospitals that filed this code at all gave us
Usable cash price — counted282
Cash price carrying a plausibility flag — shown on the compare tool, excluded here3
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded3
Hospitals that filed this code289

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as SMN1 GENE FULL GENE SEQUENCE.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Full gene sequencing of the SMN1 gene (CPT 81336) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81336-full-gene-sequencing-of-the-smn1-gene