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Procedure price report · Pathology

Gene copy number test for spinal muscular atrophy

CPT 81329the billing code this page is about

Laboratory test that counts copies of the SMN1 gene to assess spinal muscular atrophy status or carrier state; may include SMN2 copy number when performed.

Hospitals typically charge $314 cash for this outpatient procedure — the median across 1,522 hospitals that filed a usable cash price; the average of the middle 60% is $332. Most fall between $153 and $606 (20th–80th percentile).

Hospitals
1,522
States
50
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,522 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$113$173$314$528$831

The most expensive tenth of hospitals charges at least 7.4× what the cheapest tenth charges ($113 vs $831).

How the prices are spread

$90 – $116: 83 hospitals$90$116 – $148: 113 hospitals$148 – $190: 180 hospitals$148$190 – $243: 149 hospitals$243 – $311: 135 hospitals$243$311 – $398: 198 hospitals$398 – $509: 172 hospitals$398$509 – $652: 154 hospitals$652 – $835: 115 hospitals$652$835 – $1,069: 71 hospitals$835median $314price bands are equal on a log scale
Hospitals per price band (1,370 of 1,522 — the bands cover the 5th to 95th percentile)
FromToHospitals
$90$11683
$116$148113
$148$190180
$190$243149
$243$311135
$311$398198
$398$509172
$509$652154
$652$835115
$835$1,06971

By state

The median cash price in each state, against the national median of $314.

Alaska: 8 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $258 across 19 hospitalsME$258Vermont: 8 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $424 across 18 hospitalsNH$424Washington: median $368 across 43 hospitalsWA$368Idaho: 7 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 2 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $238 across 14 hospitalsND$238Minnesota: median $363 across 50 hospitalsMN$363Illinois: median $330 across 73 hospitalsIL$330Wisconsin: median $346 across 73 hospitalsWI$346Michigan: median $157 across 31 hospitalsMI$157New York: median $336 across 92 hospitalsNY$336Massachusetts: median $443 across 37 hospitalsMA$443Oregon: median $344 across 21 hospitalsOR$344Nevada: median $374 across 10 hospitalsNV$374Wyoming: 2 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 9 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $194 across 32 hospitalsIA$194Indiana: median $204 across 45 hospitalsIN$204Ohio: median $438 across 88 hospitalsOH$438Pennsylvania: median $371 across 88 hospitalsPA$371New Jersey: median $151 across 50 hospitalsNJ$151Connecticut: median $534 across 10 hospitalsCT$534Rhode Island: 5 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $314 across 61 hospitalsCA$314Utah: 6 hospitals filed a usable price — fewer than 10, so no figureUTColorado: median $463 across 29 hospitalsCO$463Nebraska: 7 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $448 across 41 hospitalsMO$448Kentucky: median $182 across 22 hospitalsKY$182West Virginia: median $300 across 21 hospitalsWV$300Virginia: median $272 across 57 hospitalsVA$272Maryland: median $375 across 22 hospitalsMD$375Delaware: 6 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $498 across 13 hospitalsAZ$498New Mexico: 6 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $1,097 across 11 hospitalsKS$1,097Arkansas: median $473 across 13 hospitalsAR$473Tennessee: median $173 across 28 hospitalsTN$173North Carolina: median $225 across 57 hospitalsNC$225South Carolina: median $584 across 21 hospitalsSC$584Oklahoma: median $320 across 20 hospitalsOK$320Louisiana: median $181 across 22 hospitalsLA$181Mississippi: median $115 across 26 hospitalsMS$115Alabama: median $209 across 12 hospitalsAL$209Georgia: median $349 across 48 hospitalsGA$349Hawaii: 4 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $290 across 77 hospitalsTX$290Florida: median $285 across 57 hospitalsFL$285
Cash price by state, most expensive first. National median $314. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Kansas KS11$1,097+250%$532 – $1,972
South Carolina SC21$584+86%$584 – $734
Connecticut CT10$534+70%$370 – $656
Arizona AZ13$498+59%$147 – $498
Arkansas AR13$473+51%$51 – $480
Colorado CO29$463+48%$262 – $648
Missouri MO41$448+43%$322 – $744
Massachusetts MA37$443+41%$214 – $513
Ohio OH88$438+40%$263 – $702
New Hampshire NH18$424+35%$142 – $1,105
Maryland MD22$375+20%$207 – $979
Nevada NV10$374+19%$143 – $480
Pennsylvania PA88$371+18%$158 – $793
Washington WA43$368+17%$142 – $706
Minnesota MN50$363+16%$122 – $528
Georgia GA48$349+11%$225 – $700
Wisconsin WI73$346+10%$125 – $758
Oregon OR21$344+10%$262 – $508
New York NY92$336+7%$137 – $563
Illinois IL73$330+5%$110 – $781
Oklahoma OK20$320+2%$103 – $415
California CA61$3140%$175 – $423
West Virginia WV21$300−4%$300 – $517
Texas TX77$290−8%$165 – $563
Florida FL57$285−9%$277 – $524
Virginia VA57$272−13%$146 – $517
Maine ME19$258−18%$156 – $505
North Dakota ND14$238−24%$200 – $535
North Carolina NC57$225−28%$82 – $315
Alabama AL12$209−33%$123 – $700
Indiana IN45$204−35%$153 – $312
Iowa IA32$194−38%$154 – $521
Kentucky KY22$182−42%$171 – $900
Louisiana LA22$181−42%$103 – $284
Tennessee TN28$173−45%$82 – $178
Michigan MI31$157−50%$110 – $271
New Jersey NJ50$151−52%$137 – $396
Mississippi MS26$115−63%$71 – $158
South Dakota SD9not enough hospitals filed a usable price
Alaska AK8not enough hospitals filed a usable price
Vermont VT8not enough hospitals filed a usable price
Idaho ID7not enough hospitals filed a usable price
Nebraska NE7not enough hospitals filed a usable price
Delaware DE6not enough hospitals filed a usable price
New Mexico NM6not enough hospitals filed a usable price
Utah UT6not enough hospitals filed a usable price
Rhode Island RI5not enough hospitals filed a usable price
Hawaii HI4not enough hospitals filed a usable price
Montana MT2not enough hospitals filed a usable price
Wyoming WY2not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $314.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,220$308$151 – $605
Children’s27$454$146 – $700
Critical access270$373$178 – $577
Ownership
For-profit134$350$149 – $716
Government202$308$163 – $612
Non-profit1,181$314$153 – $597
System affiliation
Part of a system1,336$314$151 – $584
Independent186$333$168 – $755

Cash price vs list price

Median list price (chargemaster)$568
Median cash price$314
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,101 hospitals filed a usable inpatient cash price for this code. The median is $336 and the average of the middle 60% is $348; most fall between $158 and $614.

Cash price percentiles, inpatient, across 1,101 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$116$179$336$563$793

The most expensive tenth of hospitals charges at least 6.9× what the cheapest tenth charges ($116 vs $793).

Of the 1,230 hospitals that filed this code inpatient, 1,101 gave a usable cash price; 78 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 51 a list price only.

How complete is this

1,522 of the 3,956 hospitals with a price file in our corpus (38%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,677 hospitals that filed this code at all gave us
Usable cash price — counted1,522
Cash price carrying a plausibility flag — shown on the compare tool, excluded here95
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded59
Hospitals that filed this code1,677

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as SMN1 GENE DOS/DELETION ALYS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Gene copy number test for spinal muscular atrophy (CPT 81329) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81329-gene-copy-number-test-for-spinal-muscular-atrophy