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Procedure price report · Pathology

Blood test for SEPT9 methylation, colon cancer marker

CPT 81327the billing code this page is about

Laboratory test that measures chemical methylation changes in the SEPT9 gene region, used as a marker associated with colorectal cancer.

Hospitals typically charge $290 cash for this outpatient procedure — the median across 408 hospitals that filed a usable cash price; the average of the middle 60% is $291. Most fall between $174 and $448 (20th–80th percentile).

Hospitals
408
States
41
Filings dated
Dec 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 23, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 408 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$119$192$290$400$689

The most expensive tenth of hospitals charges at least 5.8× what the cheapest tenth charges ($119 vs $689).

How the prices are spread

$86 – $112: 11 hospitals$86$112 – $146: 31 hospitals$146 – $191: 34 hospitals$146$191 – $250: 86 hospitals$250 – $326: 53 hospitals$250$326 – $426: 81 hospitals$426 – $556: 19 hospitals$426$556 – $726: 39 hospitals$726 – $948: 8 hospitals$726$948 – $1,238: 13 hospitals$948median $290price bands are equal on a log scale
Hospitals per price band (375 of 408 — the bands cover the 5th to 95th percentile)
FromToHospitals
$86$11211
$112$14631
$146$19134
$191$25086
$250$32653
$326$42681
$426$55619
$556$72639
$726$9488
$948$1,23813

By state

The median cash price in each state, against the national median of $290.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: median $183 across 16 hospitalsWA$183Idaho: 1 hospital filed a usable price — fewer than 10, so no figureIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureNDMinnesota: 1 hospital filed a usable price — fewer than 10, so no figureMNIllinois: median $400 across 27 hospitalsIL$400Wisconsin: median $290 across 20 hospitalsWI$290Michigan: 5 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $213 across 30 hospitalsNY$213Massachusetts: 2 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 5 hospitals filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 5 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $384 across 11 hospitalsIA$384Indiana: median $238 across 26 hospitalsIN$238Ohio: median $194 across 14 hospitalsOH$194Pennsylvania: median $554 across 23 hospitalsPA$554New Jersey: median $211 across 26 hospitalsNJ$211Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $689 across 23 hospitalsCA$689Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: median $249 across 19 hospitalsCO$249Nebraska: 1 hospital filed a usable price — fewer than 10, so no figureNEMissouri: 9 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $1,238 across 10 hospitalsKY$1,238West Virginia: 3 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $181 across 22 hospitalsVA$181Maryland: 5 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 1 hospital filed a usable price — fewer than 10, so no figureAZNew Mexico: 2 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 5 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 6 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: 3 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 4 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: no hospital in the corpus filed a usable priceMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: 9 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $377 across 35 hospitalsTX$377Florida: median $228 across 21 hospitalsFL$228
Cash price by state, most expensive first. National median $290. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Kentucky KY10$1,238+327%$176 – $1,238
California CA23$689+138%$689 – $689
Pennsylvania PA23$554+91%$49 – $1,593
Illinois IL27$400+38%$348 – $444
Iowa IA11$384+32%$384 – $384
Texas TX35$377+30%$359 – $377
Wisconsin WI20$2900%$290 – $319
Colorado CO19$249−14%$114 – $318
Indiana IN26$238−18%$132 – $312
Florida FL21$228−21%$185 – $228
New York NY30$213−27%$192 – $648
New Jersey NJ26$211−27%$192 – $211
Ohio OH14$194−33%$111 – $861
Washington WA16$183−37%$138 – $261
Virginia VA22$181−38%$174 – $248
Georgia GA9not enough hospitals filed a usable price
Missouri MO9not enough hospitals filed a usable price
Tennessee TN6not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Kansas KS5not enough hospitals filed a usable price
Maryland MD5not enough hospitals filed a usable price
Michigan MI5not enough hospitals filed a usable price
Oregon OR5not enough hospitals filed a usable price
Wyoming WY5not enough hospitals filed a usable price
Louisiana LA4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
North Carolina NC3not enough hospitals filed a usable price
West Virginia WV3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Massachusetts MA2not enough hospitals filed a usable price
New Mexico NM2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Arizona AZ1not enough hospitals filed a usable price
Idaho ID1not enough hospitals filed a usable price
Minnesota MN1not enough hospitals filed a usable price
North Dakota ND1not enough hospitals filed a usable price
Nebraska NE1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $290.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care343$277$172 – $491
Children’s2fewer than 20 hospitals
Critical access63$319$204 – $444
Ownership
For-profit32$361$225 – $576
Government46$237$172 – $371
Non-profit330$290$174 – $468
System affiliation
Part of a system367$280$172 – $444
Independent41$312$221 – $481

Cash price vs list price

Median list price (chargemaster)$540
Median cash price$290
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

268 hospitals filed a usable inpatient cash price for this code. The median is $318 and the average of the middle 60% is $297; most fall between $160 and $576.

Cash price percentiles, inpatient, across 268 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$111$172$318$400$689

The most expensive tenth of hospitals charges at least 6.2× what the cheapest tenth charges ($111 vs $689).

Of the 286 hospitals that filed this code inpatient, 268 gave a usable cash price; 7 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 11 a list price only.

How complete is this

408 of the 3,956 hospitals with a price file in our corpus (10%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 430 hospitals that filed this code at all gave us
Usable cash price — counted408
Cash price carrying a plausibility flag — shown on the compare tool, excluded here9
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded11
Hospitals that filed this code430

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 23, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as SEPT9 GEN PRMTR MTHYLTN ALYS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Blood test for SEPT9 methylation, colon cancer marker (CPT 81327) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81327-blood-test-for-sept9-methylation-colon-cancer-marker