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Procedure price report · Pathology

Full gene sequencing of the PMS2 gene

CPT 81317the billing code this page is about

Laboratory test that reads the entire coding sequence of the PMS2 gene, one of the mismatch repair genes linked to hereditary colorectal and other cancers.

Hospitals typically charge $891 cash for this outpatient procedure — the median across 715 hospitals that filed a usable cash price; the average of the middle 60% is $956. Most fall between $399 and $1,737 (20th–80th percentile).

Hospitals
715
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 715 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$270$490$891$1,546$2,583

The most expensive tenth of hospitals charges at least 9.6× what the cheapest tenth charges ($270 vs $2,583).

How the prices are spread

$158 – $215: 13 hospitals$158$215 – $293: 58 hospitals$293 – $400: 41 hospitals$293$400 – $544: 53 hospitals$544 – $742: 97 hospitals$544$742 – $1,010: 105 hospitals$1,010 – $1,376: 84 hospitals$1,010$1,376 – $1,875: 106 hospitals$1,875 – $2,555: 46 hospitals$1,875$2,555 – $3,481: 42 hospitals$2,555median $891price bands are equal on a log scale
Hospitals per price band (645 of 715 — the bands cover the 5th to 95th percentile)
FromToHospitals
$158$21513
$215$29358
$293$40041
$400$54453
$544$74297
$742$1,010105
$1,010$1,37684
$1,376$1,875106
$1,875$2,55546
$2,555$3,48142

By state

The median cash price in each state, against the national median of $891.

Alaska: 5 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 2 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 3 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $1,245 across 26 hospitalsWA$1,245Idaho: 3 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 2 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $1,177 across 13 hospitalsND$1,177Minnesota: median $891 across 11 hospitalsMN$891Illinois: median $1,294 across 36 hospitalsIL$1,294Wisconsin: median $2,334 across 24 hospitalsWI$2,334Michigan: median $934 across 13 hospitalsMI$934New York: median $710 across 41 hospitalsNY$710Massachusetts: median $2,101 across 20 hospitalsMA$2,101Oregon: median $630 across 14 hospitalsOR$630Nevada: 7 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 3 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $649 across 16 hospitalsIA$649Indiana: median $744 across 35 hospitalsIN$744Ohio: median $1,544 across 34 hospitalsOH$1,544Pennsylvania: median $1,127 across 44 hospitalsPA$1,127New Jersey: median $744 across 31 hospitalsNJ$744Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 2 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $1,546 across 31 hospitalsCA$1,546Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: median $713 across 17 hospitalsCO$713Nebraska: 5 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $1,061 across 14 hospitalsMO$1,061Kentucky: median $1,651 across 15 hospitalsKY$1,651West Virginia: 5 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $1,870 across 16 hospitalsVA$1,870Maryland: median $519 across 13 hospitalsMD$519Delaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 4 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 3 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $1,065 across 11 hospitalsKS$1,065Arkansas: 5 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $1,003 across 15 hospitalsTN$1,003North Carolina: median $861 across 19 hospitalsNC$861South Carolina: median $1,057 across 10 hospitalsSC$1,057Oklahoma: 9 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: median $361 across 18 hospitalsLA$361Mississippi: 7 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 2 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $568 across 13 hospitalsGA$568Hawaii: 3 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $290 across 57 hospitalsTX$290Florida: median $1,132 across 30 hospitalsFL$1,132
Cash price by state, most expensive first. National median $891. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Wisconsin WI24$2,334+162%$1,130 – $5,435
Massachusetts MA20$2,101+136%$1,371 – $2,445
Virginia VA16$1,870+110%$1,003 – $2,583
Kentucky KY15$1,651+85%$518 – $2,841
California CA31$1,546+74%$171 – $1,546
Ohio OH34$1,544+73%$1,078 – $2,183
Illinois IL36$1,294+45%$825 – $1,421
Washington WA26$1,245+40%$508 – $2,224
North Dakota ND13$1,177+32%$904 – $2,030
Florida FL30$1,132+27%$80 – $2,368
Pennsylvania PA44$1,127+27%$399 – $4,623
Kansas KS11$1,065+20%$710 – $2,328
Missouri MO14$1,061+19%$490 – $1,549
South Carolina SC10$1,057+19%$736 – $1,057
Tennessee TN15$1,003+13%$560 – $1,003
Michigan MI13$934+5%$143 – $1,006
Minnesota MN11$8910%$891 – $891
North Carolina NC19$861−3%$376 – $897
Indiana IN35$744−16%$247 – $1,292
New Jersey NJ31$744−16%$677 – $1,266
Colorado CO17$713−20%$280 – $877
New York NY41$710−20%$677 – $1,500
Iowa IA16$649−27%$420 – $649
Oregon OR14$630−29%$300 – $2,163
Georgia GA13$568−36%$468 – $2,760
Maryland MD13$519−42%$380 – $683
Louisiana LA18$361−59%$233 – $820
Texas TX57$290−67%$290 – $1,337
Oklahoma OK9not enough hospitals filed a usable price
Mississippi MS7not enough hospitals filed a usable price
Nevada NV7not enough hospitals filed a usable price
Alaska AK5not enough hospitals filed a usable price
Arkansas AR5not enough hospitals filed a usable price
Nebraska NE5not enough hospitals filed a usable price
West Virginia WV5not enough hospitals filed a usable price
Arizona AZ4not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Hawaii HI3not enough hospitals filed a usable price
Idaho ID3not enough hospitals filed a usable price
New Mexico NM3not enough hospitals filed a usable price
Vermont VT3not enough hospitals filed a usable price
Wyoming WY3not enough hospitals filed a usable price
Alabama AL2not enough hospitals filed a usable price
Maine ME2not enough hospitals filed a usable price
Montana MT2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
Rhode Island RI2not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $891.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care581$861$389 – $1,617
Children’s11fewer than 20 hospitals
Critical access118$1,070$447 – $2,182
Ownership
For-profit49$974$290 – $2,131
Government102$810$453 – $1,184
Non-profit559$900$399 – $1,796
System affiliation
Part of a system604$891$399 – $1,748
Independent111$796$450 – $1,624

Cash price vs list price

Median list price (chargemaster)$1,500
Median cash price$891
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

497 hospitals filed a usable inpatient cash price for this code. The median is $1,003 and the average of the middle 60% is $1,008; most fall between $399 and $1,767.

Cash price percentiles, inpatient, across 497 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$290$518$1,003$1,546$2,590

The most expensive tenth of hospitals charges at least 8.9× what the cheapest tenth charges ($290 vs $2,590).

Of the 589 hospitals that filed this code inpatient, 497 gave a usable cash price; 60 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 32 a list price only.

How complete is this

715 of the 3,956 hospitals with a price file in our corpus (18%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 821 hospitals that filed this code at all gave us
Usable cash price — counted715
Cash price carrying a plausibility flag — shown on the compare tool, excluded here78
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded27
Hospitals that filed this code821

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as PMS2 GENE FULL SEQ ANALYSIS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Full gene sequencing of the PMS2 gene (CPT 81317) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81317-full-gene-sequencing-of-the-pms2-gene