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Procedure price report · Pathology

Leukemia gene fusion test for one breakpoint region

CPT 81316the billing code this page is about

Laboratory test on blood or bone marrow that looks for the PML/RARalpha gene fusion seen in acute promyelocytic leukemia; this code covers testing of a single breakpoint or breakpoint set.

Hospitals typically charge $307 cash for this outpatient procedure — the median across 183 hospitals that filed a usable cash price; the average of the middle 60% is $450. Most fall between $207 and $1,347 (20th–80th percentile).

Hospitals
183
States
27
Filings dated
Dec 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 183 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$161$207$307$1,114$2,929

The most expensive tenth of hospitals charges at least 18× what the cheapest tenth charges ($161 vs $2,929).

How the prices are spread

$48 – $72: 1 hospitals$48$72 – $109: 2 hospitals$109 – $165: 8 hospitals$109$165 – $249: 44 hospitals$249 – $375: 38 hospitals$249$375 – $566: 20 hospitals$566 – $853: 8 hospitals$566$853 – $1,287: 16 hospitals$1,287 – $1,942: 10 hospitals$1,287$1,942 – $2,929: 25 hospitals$1,942median $307price bands are equal on a log scale
Hospitals per price band (172 of 183 — the bands cover the 5th to 95th percentile)
FromToHospitals
$48$721
$72$1092
$109$1658
$165$24944
$249$37538
$375$56620
$566$8538
$853$1,28716
$1,287$1,94210
$1,942$2,92925

By state

The median cash price in each state, against the national median of $307.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: 7 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: 1 hospital filed a usable price — fewer than 10, so no figureMNIllinois: 3 hospitals filed a usable price — fewer than 10, so no figureILWisconsin: no hospital in the corpus filed a usable priceWIMichigan: 4 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $207 across 12 hospitalsNY$207Massachusetts: 1 hospital filed a usable price — fewer than 10, so no figureMAOregon: 3 hospitals filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $520 across 11 hospitalsIA$520Indiana: median $334 across 13 hospitalsIN$334Ohio: 1 hospital filed a usable price — fewer than 10, so no figureOHPennsylvania: median $548 across 27 hospitalsPA$548New Jersey: median $228 across 22 hospitalsNJ$228Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $2,929 across 21 hospitalsCA$2,929Utah: no hospital in the corpus filed a usable priceUTColorado: no hospital in the corpus filed a usable priceCONebraska: no hospital in the corpus filed a usable priceNEMissouri: no hospital in the corpus filed a usable priceMOKentucky: 2 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: no hospital in the corpus filed a usable priceWVVirginia: 5 hospitals filed a usable price — fewer than 10, so no figureVAMaryland: no hospital in the corpus filed a usable priceMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 1 hospital filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: no hospital in the corpus filed a usable priceKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 5 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: no hospital in the corpus filed a usable priceNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 1 hospital filed a usable price — fewer than 10, so no figureLAMississippi: median $175 across 11 hospitalsMS$175Alabama: no hospital in the corpus filed a usable priceALGeorgia: 6 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $307 across 16 hospitalsTX$307Florida: 1 hospital filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $307. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA21$2,929+854%$2,929 – $2,929
Pennsylvania PA27$548+78%$27 – $1,114
Iowa IA11$520+69%$520 – $520
Indiana IN13$334+9%$292 – $449
Texas TX16$3070%$307 – $307
New Jersey NJ22$228−26%$207 – $228
New York NY12$207−33%$207 – $207
Mississippi MS11$175−43%$161 – $308
Washington WA7not enough hospitals filed a usable price
Georgia GA6not enough hospitals filed a usable price
Tennessee TN5not enough hospitals filed a usable price
Virginia VA5not enough hospitals filed a usable price
Michigan MI4not enough hospitals filed a usable price
Illinois IL3not enough hospitals filed a usable price
Oregon OR3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
Kentucky KY2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Arizona AZ1not enough hospitals filed a usable price
Florida FL1not enough hospitals filed a usable price
Louisiana LA1not enough hospitals filed a usable price
Massachusetts MA1not enough hospitals filed a usable price
Minnesota MN1not enough hospitals filed a usable price
Ohio OH1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $307.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care159$307$207 – $1,489
Children’s4fewer than 20 hospitals
Critical access20$449$308 – $937
Ownership
For-profit11fewer than 20 hospitals
Government15fewer than 20 hospitals
Non-profit157$308$207 – $1,489
System affiliation
Part of a system172$307$207 – $1,489
Independent11fewer than 20 hospitals

Cash price vs list price

Median list price (chargemaster)$700
Median cash price$307
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

106 hospitals filed a usable inpatient cash price for this code. The median is $520 and the average of the middle 60% is $855; most fall between $197 and $2,669.

Cash price percentiles, inpatient, across 106 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$138$287$520$1,672$2,929

The most expensive tenth of hospitals charges at least 21× what the cheapest tenth charges ($138 vs $2,929).

Of the 110 hospitals that filed this code inpatient, 106 gave a usable cash price; 3 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 1 a list price only.

How complete is this

183 of the 3,956 hospitals with a price file in our corpus (5%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 189 hospitals that filed this code at all gave us
Usable cash price — counted183
Cash price carrying a plausibility flag — shown on the compare tool, excluded here4
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded1
Hospitals that filed this code189

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as PML/RARALPHA 1 BREAKPOINT.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Leukemia gene fusion test for one breakpoint region (CPT 81316) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81316-leukemia-gene-fusion-test-for-one-breakpoint-region