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Procedure price report · Pathology

NPM1 gene test for variants in one region

CPT 81310the billing code this page is about

A test of blood or bone marrow for changes in a specific region of the NPM1 gene, used in evaluating acute myeloid leukemia.

Hospitals typically charge $403 cash for this outpatient procedure — the median across 1,508 hospitals that filed a usable cash price; the average of the middle 60% is $421. Most fall between $237 and $758 (20th–80th percentile).

Hospitals
1,508
States
49
Filings dated
Jun 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,508 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$173$252$403$664$1,042

The most expensive tenth of hospitals charges at least 6.0× what the cheapest tenth charges ($173 vs $1,042).

How the prices are spread

$117 – $147: 41 hospitals$117$147 – $184: 54 hospitals$184 – $231: 123 hospitals$184$231 – $290: 197 hospitals$290 – $364: 195 hospitals$290$364 – $457: 205 hospitals$457 – $573: 183 hospitals$457$573 – $720: 91 hospitals$720 – $903: 108 hospitals$720$903 – $1,133: 162 hospitals$903median $403price bands are equal on a log scale
Hospitals per price band (1,359 of 1,508 — the bands cover the 5th to 95th percentile)
FromToHospitals
$117$14741
$147$18454
$184$231123
$231$290197
$290$364195
$364$457205
$457$573183
$573$72091
$720$903108
$903$1,133162

By state

The median cash price in each state, against the national median of $403.

Alaska: 9 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $230 across 11 hospitalsME$230Vermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 7 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $392 across 45 hospitalsWA$392Idaho: median $338 across 12 hospitalsID$338Montana: 3 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 3 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $395 across 51 hospitalsMN$395Illinois: median $617 across 52 hospitalsIL$617Wisconsin: median $508 across 55 hospitalsWI$508Michigan: median $340 across 52 hospitalsMI$340New York: median $433 across 58 hospitalsNY$433Massachusetts: median $770 across 29 hospitalsMA$770Oregon: median $332 across 17 hospitalsOR$332Nevada: 9 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 6 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 2 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $237 across 18 hospitalsIA$237Indiana: median $358 across 44 hospitalsIN$358Ohio: median $502 across 92 hospitalsOH$502Pennsylvania: median $284 across 74 hospitalsPA$284New Jersey: median $271 across 41 hospitalsNJ$271Connecticut: median $618 across 11 hospitalsCT$618Rhode Island: 4 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $503 across 64 hospitalsCA$503Utah: median $931 across 23 hospitalsUT$931Colorado: median $398 across 39 hospitalsCO$398Nebraska: 7 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $544 across 41 hospitalsMO$544Kentucky: median $321 across 28 hospitalsKY$321West Virginia: median $458 across 24 hospitalsWV$458Virginia: median $317 across 42 hospitalsVA$317Maryland: median $424 across 19 hospitalsMD$424Delaware: 4 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $412 across 27 hospitalsAZ$412New Mexico: median $279 across 10 hospitalsNM$279Kansas: median $823 across 21 hospitalsKS$823Arkansas: median $431 across 17 hospitalsAR$431Tennessee: median $278 across 42 hospitalsTN$278North Carolina: median $237 across 44 hospitalsNC$237South Carolina: median $445 across 32 hospitalsSC$445Oklahoma: median $313 across 32 hospitalsOK$313Louisiana: median $278 across 19 hospitalsLA$278Mississippi: median $136 across 19 hospitalsMS$136Alabama: median $272 across 11 hospitalsAL$272Georgia: median $424 across 57 hospitalsGA$424Hawaii: 9 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $404 across 116 hospitalsTX$404Florida: median $216 across 56 hospitalsFL$216
Cash price by state, most expensive first. National median $403. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT23$931+131%$931 – $1,095
Kansas KS21$823+104%$316 – $1,042
Massachusetts MA29$770+91%$365 – $1,019
Connecticut CT11$618+53%$209 – $1,048
Illinois IL52$617+53%$325 – $1,015
Missouri MO41$544+35%$454 – $927
Wisconsin WI55$508+26%$354 – $980
California CA64$503+25%$126 – $566
Ohio OH92$502+25%$348 – $1,106
West Virginia WV24$458+14%$419 – $959
South Carolina SC32$445+10%$238 – $614
New York NY58$433+7%$247 – $723
Arkansas AR17$431+7%$199 – $534
Maryland MD19$424+5%$224 – $577
Georgia GA57$424+5%$322 – $1,010
Arizona AZ27$412+2%$267 – $1,059
Texas TX116$4040%$257 – $664
Colorado CO39$398−1%$282 – $1,118
Minnesota MN51$395−2%$89 – $519
Washington WA45$392−3%$181 – $674
Indiana IN44$358−11%$266 – $480
Michigan MI52$340−16%$220 – $563
Idaho ID12$338−16%$338 – $575
Oregon OR17$332−18%$332 – $532
Kentucky KY28$321−20%$225 – $407
Virginia VA42$317−21%$268 – $476
Oklahoma OK32$313−22%$210 – $528
Pennsylvania PA74$284−30%$170 – $890
New Mexico NM10$279−31%$274 – $939
Tennessee TN42$278−31%$210 – $372
Louisiana LA19$278−31%$146 – $370
Alabama AL11$272−33%$206 – $2,122
New Jersey NJ41$271−33%$247 – $403
North Carolina NC44$237−41%$148 – $605
Iowa IA18$237−41%$237 – $476
Maine ME11$230−43%$217 – $407
Florida FL56$216−46%$148 – $270
Mississippi MS19$136−66%$114 – $247
Alaska AK9not enough hospitals filed a usable price
Hawaii HI9not enough hospitals filed a usable price
Nevada NV9not enough hospitals filed a usable price
Nebraska NE7not enough hospitals filed a usable price
New Hampshire NH7not enough hospitals filed a usable price
Wyoming WY6not enough hospitals filed a usable price
Delaware DE4not enough hospitals filed a usable price
Rhode Island RI4not enough hospitals filed a usable price
Montana MT3not enough hospitals filed a usable price
North Dakota ND3not enough hospitals filed a usable price
South Dakota SD2not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $403.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,257$383$231 – $762
Children’s29$370$145 – $766
Critical access214$468$312 – $738
Ownership
For-profit163$404$246 – $1,012
Government170$322$225 – $602
Non-profit1,167$404$237 – $740
System affiliation
Part of a system1,367$404$237 – $777
Independent141$334$206 – $575

Cash price vs list price

Median list price (chargemaster)$740
Median cash price$403
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,141 hospitals filed a usable inpatient cash price for this code. The median is $404 and the average of the middle 60% is $444; most fall between $237 and $820.

Cash price percentiles, inpatient, across 1,141 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$174$267$404$713$1,044

The most expensive tenth of hospitals charges at least 6.0× what the cheapest tenth charges ($174 vs $1,044).

Of the 1,251 hospitals that filed this code inpatient, 1,141 gave a usable cash price; 75 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 35 a list price only.

How complete is this

1,508 of the 3,956 hospitals with a price file in our corpus (38%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,638 hospitals that filed this code at all gave us
Usable cash price — counted1,508
Cash price carrying a plausibility flag — shown on the compare tool, excluded here93
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded35
Hospitals that filed this code1,638

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Npm1 Ngs.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “NPM1 gene test for variants in one region (CPT 81310) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81310-npm1-gene-test-for-variants-in-one-region