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Procedure price report · Pathology

PIK3CA gene test of selected regions

CPT 81309the billing code this page is about

A targeted test of specific regions of the PIK3CA gene in tumor or blood samples to detect changes that affect cancer classification and treatment choice.

Hospitals typically charge $479 cash for this outpatient procedure — the median across 554 hospitals that filed a usable cash price; the average of the middle 60% is $510. Most fall between $275 and $956 (20th–80th percentile).

Hospitals
554
States
43
Filings dated
Jan 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 554 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$206$302$479$811$1,375

The most expensive tenth of hospitals charges at least 6.7× what the cheapest tenth charges ($206 vs $1,375).

How the prices are spread

$159 – $209: 36 hospitals$159$209 – $275: 56 hospitals$275 – $362: 66 hospitals$275$362 – $477: 88 hospitals$477 – $627: 75 hospitals$477$627 – $825: 80 hospitals$825 – $1,085: 55 hospitals$825$1,085 – $1,427: 22 hospitals$1,427 – $1,877: 16 hospitals$1,427$1,877 – $2,470: 27 hospitals$1,877median $479price bands are equal on a log scale
Hospitals per price band (521 of 554 — the bands cover the 5th to 95th percentile)
FromToHospitals
$159$20936
$209$27556
$275$36266
$362$47788
$477$62775
$627$82580
$825$1,08555
$1,085$1,42722
$1,427$1,87716
$1,877$2,47027

By state

The median cash price in each state, against the national median of $479.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: median $214 across 10 hospitalsME$214Vermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: median $386 across 24 hospitalsWA$386Idaho: no hospital in the corpus filed a usable priceIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $804 across 24 hospitalsMN$804Illinois: median $513 across 16 hospitalsIL$513Wisconsin: median $1,080 across 12 hospitalsWI$1,080Michigan: 7 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $289 across 23 hospitalsNY$289Massachusetts: 9 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 1 hospital filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $264 across 14 hospitalsIA$264Indiana: median $1,448 across 21 hospitalsIN$1,448Ohio: median $836 across 37 hospitalsOH$836Pennsylvania: median $191 across 15 hospitalsPA$191New Jersey: median $302 across 25 hospitalsNJ$302Connecticut: 2 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $2,470 across 36 hospitalsCA$2,470Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: 8 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 3 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 7 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $824 across 19 hospitalsKY$824West Virginia: 8 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $384 across 25 hospitalsVA$384Maryland: 9 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: no hospital in the corpus filed a usable priceDEArizona: median $1,036 across 14 hospitalsAZ$1,036New Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: no hospital in the corpus filed a usable priceKSArkansas: 5 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $222 across 14 hospitalsTN$222North Carolina: median $414 across 11 hospitalsNC$414South Carolina: 7 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: median $206 across 12 hospitalsOK$206Louisiana: 3 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: median $232 across 11 hospitalsMS$232Alabama: 2 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $453 across 16 hospitalsGA$453Hawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $586 across 60 hospitalsTX$586Florida: median $331 across 28 hospitalsFL$331
Cash price by state, most expensive first. National median $479. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA36$2,470+416%$479 – $2,470
Indiana IN21$1,448+202%$468 – $1,833
Wisconsin WI12$1,080+126%$531 – $1,080
Arizona AZ14$1,036+116%$370 – $1,036
Ohio OH37$836+75%$338 – $1,232
Kentucky KY19$824+72%$335 – $1,065
Minnesota MN24$804+68%$323 – $1,056
Texas TX60$586+22%$287 – $633
Illinois IL16$513+7%$513 – $689
Georgia GA16$453−5%$453 – $624
North Carolina NC11$414−13%$392 – $414
Washington WA24$386−19%$232 – $761
Virginia VA25$384−20%$373 – $652
Florida FL28$331−31%$159 – $665
New Jersey NJ25$302−37%$275 – $302
New York NY23$289−40%$275 – $647
Iowa IA14$264−45%$264 – $300
Mississippi MS11$232−52%$213 – $417
Tennessee TN14$222−54%$178 – $423
Maine ME10$214−55%$173 – $320
Oklahoma OK12$206−57%$141 – $266
Pennsylvania PA15$191−60%$151 – $911
Massachusetts MA9not enough hospitals filed a usable price
Maryland MD9not enough hospitals filed a usable price
Colorado CO8not enough hospitals filed a usable price
West Virginia WV8not enough hospitals filed a usable price
Michigan MI7not enough hospitals filed a usable price
Missouri MO7not enough hospitals filed a usable price
South Carolina SC7not enough hospitals filed a usable price
Arkansas AR5not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price
Louisiana LA3not enough hospitals filed a usable price
Nebraska NE3not enough hospitals filed a usable price
Alabama AL2not enough hospitals filed a usable price
Connecticut CT2not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
Oregon OR1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $479.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care467$479$275 – $877
Children’s13fewer than 20 hospitals
Critical access73$593$373 – $1,056
Ownership
For-profit38$633$320 – $1,036
Government77$385$275 – $606
Non-profit438$497$275 – $1,056
System affiliation
Part of a system510$479$275 – $1,036
Independent44$415$275 – $858

Cash price vs list price

Median list price (chargemaster)$921
Median cash price$479
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

404 hospitals filed a usable inpatient cash price for this code. The median is $483 and the average of the middle 60% is $550; most fall between $287 and $1,036.

Cash price percentiles, inpatient, across 404 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$215$323$483$811$1,232

The most expensive tenth of hospitals charges at least 5.7× what the cheapest tenth charges ($215 vs $1,232).

Of the 460 hospitals that filed this code inpatient, 404 gave a usable cash price; 39 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 17 a list price only.

How complete is this

554 of the 3,956 hospitals with a price file in our corpus (14%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 608 hospitals that filed this code at all gave us
Usable cash price — counted554
Cash price carrying a plausibility flag — shown on the compare tool, excluded here35
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded18
Hospitals that filed this code608

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as PIK3CA GENE TRGT SEQ ALYS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “PIK3CA gene test of selected regions (CPT 81309) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81309-pik3ca-gene-test-of-selected-regions