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Procedure price report · Pathology

MECP2 gene test for missing or extra gene segments

CPT 81304the billing code this page is about

A test that checks the MECP2 gene for deleted or duplicated pieces rather than single-letter changes.

Hospitals typically charge $292 cash for this outpatient procedure — the median across 375 hospitals that filed a usable cash price; the average of the middle 60% is $332. Most fall between $154 and $758 (20th–80th percentile).

Hospitals
375
States
39
Filings dated
Feb 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 375 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$116$158$292$636$1,075

The most expensive tenth of hospitals charges at least 9.3× what the cheapest tenth charges ($116 vs $1,075).

How the prices are spread

$66 – $88: 4 hospitals$66$88 – $119: 18 hospitals$119 – $160: 67 hospitals$119$160 – $216: 38 hospitals$216 – $291: 42 hospitals$216$291 – $392: 58 hospitals$392 – $528: 24 hospitals$392$528 – $712: 22 hospitals$712 – $960: 37 hospitals$712$960 – $1,293: 29 hospitals$960median $292price bands are equal on a log scale
Hospitals per price band (339 of 375 — the bands cover the 5th to 95th percentile)
FromToHospitals
$66$884
$88$11918
$119$16067
$160$21638
$216$29142
$291$39258
$392$52824
$528$71222
$712$96037
$960$1,29329

By state

The median cash price in each state, against the national median of $292.

Alaska: no hospital in the corpus filed a usable priceAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: median $252 across 11 hospitalsWA$252Idaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 3 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: 1 hospital filed a usable price — fewer than 10, so no figureMNIllinois: median $630 across 23 hospitalsIL$630Wisconsin: median $1,075 across 13 hospitalsWI$1,075Michigan: 9 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $150 across 29 hospitalsNY$150Massachusetts: 9 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 1 hospital filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $154 across 13 hospitalsIA$154Indiana: median $218 across 15 hospitalsIN$218Ohio: median $298 across 23 hospitalsOH$298Pennsylvania: median $80 across 17 hospitalsPA$80New Jersey: median $165 across 25 hospitalsNJ$165Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $342 across 21 hospitalsCA$342Utah: no hospital in the corpus filed a usable priceUTColorado: 3 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 2 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 9 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 3 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: 7 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $158 across 11 hospitalsVA$158Maryland: 4 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 2 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 2 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $158 across 15 hospitalsTN$158North Carolina: 8 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: 3 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 9 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 1 hospital filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: 9 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $598 across 48 hospitalsTX$598Florida: median $158 across 12 hospitalsFL$158
Cash price by state, most expensive first. National median $292. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Wisconsin WI13$1,075+268%$345 – $1,075
Illinois IL23$630+116%$285 – $1,155
Texas TX48$598+104%$228 – $758
California CA21$342+17%$342 – $342
Ohio OH23$298+2%$295 – $673
Washington WA11$252−14%$227 – $252
Indiana IN15$218−26%$188 – $308
New Jersey NJ25$165−44%$150 – $165
Tennessee TN15$158−46%$124 – $158
Virginia VA11$158−46%$158 – $1,123
Florida FL12$158−46%$158 – $339
Iowa IA13$154−47%$154 – $154
New York NY29$150−49%$103 – $225
Pennsylvania PA17$80−73%$63 – $323
Georgia GA9not enough hospitals filed a usable price
Louisiana LA9not enough hospitals filed a usable price
Massachusetts MA9not enough hospitals filed a usable price
Michigan MI9not enough hospitals filed a usable price
Missouri MO9not enough hospitals filed a usable price
North Carolina NC8not enough hospitals filed a usable price
West Virginia WV7not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Maryland MD4not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
Colorado CO3not enough hospitals filed a usable price
Kentucky KY3not enough hospitals filed a usable price
North Dakota ND3not enough hospitals filed a usable price
Oklahoma OK3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Kansas KS2not enough hospitals filed a usable price
Nebraska NE2not enough hospitals filed a usable price
New Mexico NM2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Minnesota MN1not enough hospitals filed a usable price
Mississippi MS1not enough hospitals filed a usable price
Oregon OR1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $292.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care311$285$154 – $758
Children’s28$335$47 – $1,366
Critical access36$298$155 – $525
Ownership
For-profit21$330$124 – $758
Government35$173$150 – $669
Non-profit319$295$154 – $758
System affiliation
Part of a system342$292$154 – $736
Independent33$265$54 – $1,124

Cash price vs list price

Median list price (chargemaster)$610
Median cash price$292
Cash as a share of list, median hospital54%

At the typical hospital, asking for the cash price cuts the list price by about 46%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

268 hospitals filed a usable inpatient cash price for this code. The median is $342 and the average of the middle 60% is $381; most fall between $158 and $736.

Cash price percentiles, inpatient, across 268 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$124$175$342$669$1,075

The most expensive tenth of hospitals charges at least 8.6× what the cheapest tenth charges ($124 vs $1,075).

Of the 309 hospitals that filed this code inpatient, 268 gave a usable cash price; 36 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 5 a list price only.

How complete is this

375 of the 3,956 hospitals with a price file in our corpus (9%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 418 hospitals that filed this code at all gave us
Usable cash price — counted375
Cash price carrying a plausibility flag — shown on the compare tool, excluded here36
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded6
Hospitals that filed this code418

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MECP2 GENE DUP/DELET VARIANT.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MECP2 gene test for missing or extra gene segments (CPT 81304) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81304-mecp2-gene-test-for-missing-or-extra-gene-segments