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Procedure price report · Pathology

MECP2 gene test for a known family variant

CPT 81303the billing code this page is about

A test that looks only for a specific MECP2 gene change already identified in a relative, rather than sequencing the whole gene.

Hospitals typically charge $237 cash for this outpatient procedure — the median across 195 hospitals that filed a usable cash price; the average of the middle 60% is $218. Most fall between $132 and $388 (20th–80th percentile).

Hospitals
195
States
32
Filings dated
Aug 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 195 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$120$144$237$335$612

The most expensive tenth of hospitals charges at least 5.1× what the cheapest tenth charges ($120 vs $612).

How the prices are spread

$110 – $135: 36 hospitals$110$135 – $165: 25 hospitals$165 – $201: 20 hospitals$165$201 – $247: 22 hospitals$247 – $302: 30 hospitals$247$302 – $369: 12 hospitals$369 – $452: 18 hospitals$369$452 – $553: 1 hospitals$553 – $676: 7 hospitals$553$676 – $827: 11 hospitals$676median $237price bands are equal on a log scale
Hospitals per price band (182 of 195 — the bands cover the 5th to 95th percentile)
FromToHospitals
$110$13536
$135$16525
$165$20120
$201$24722
$247$30230
$302$36912
$369$45218
$452$5531
$553$6767
$676$82711

By state

The median cash price in each state, against the national median of $237.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 1 hospital filed a usable price — fewer than 10, so no figureNHWashington: 3 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: no hospital in the corpus filed a usable priceMNIllinois: 6 hospitals filed a usable price — fewer than 10, so no figureILWisconsin: no hospital in the corpus filed a usable priceWIMichigan: median $442 across 14 hospitalsMI$442New York: median $120 across 15 hospitalsNY$120Massachusetts: 2 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 3 hospitals filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $240 across 11 hospitalsIA$240Indiana: median $173 across 12 hospitalsIN$173Ohio: median $820 across 18 hospitalsOH$820Pennsylvania: median $202 across 14 hospitalsPA$202New Jersey: median $132 across 22 hospitalsNJ$132Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $274 across 20 hospitalsCA$274Utah: no hospital in the corpus filed a usable priceUTColorado: 2 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 2 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 7 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 1 hospital filed a usable price — fewer than 10, so no figureKYWest Virginia: no hospital in the corpus filed a usable priceWVVirginia: 5 hospitals filed a usable price — fewer than 10, so no figureVAMaryland: 2 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 2 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 1 hospital filed a usable price — fewer than 10, so no figureTNNorth Carolina: no hospital in the corpus filed a usable priceNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: 3 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 1 hospital filed a usable price — fewer than 10, so no figureLAMississippi: 2 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: no hospital in the corpus filed a usable priceALGeorgia: 2 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $144 across 16 hospitalsTX$144Florida: 1 hospital filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $237. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Ohio OH18$820+246%$612 – $827
Michigan MI14$442+86%$166 – $442
California CA20$274+16%$274 – $274
Iowa IA11$240+1%$240 – $240
Pennsylvania PA14$202−15%$79 – $247
Indiana IN12$173−27%$152 – $234
Texas TX16$144−39%$144 – $144
New Jersey NJ22$132−44%$120 – $132
New York NY15$120−49%$120 – $144
Missouri MO7not enough hospitals filed a usable price
Illinois IL6not enough hospitals filed a usable price
Virginia VA5not enough hospitals filed a usable price
Oklahoma OK3not enough hospitals filed a usable price
Oregon OR3not enough hospitals filed a usable price
Washington WA3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Arizona AZ2not enough hospitals filed a usable price
Colorado CO2not enough hospitals filed a usable price
Georgia GA2not enough hospitals filed a usable price
Massachusetts MA2not enough hospitals filed a usable price
Maryland MD2not enough hospitals filed a usable price
Mississippi MS2not enough hospitals filed a usable price
Nebraska NE2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Florida FL1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
Kentucky KY1not enough hospitals filed a usable price
Louisiana LA1not enough hospitals filed a usable price
New Hampshire NH1not enough hospitals filed a usable price
Tennessee TN1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $237.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care163$182$132 – $330
Children’s12fewer than 20 hospitals
Critical access18fewer than 20 hospitals
Ownership
For-profit10fewer than 20 hospitals
Government21$138$120 – $335
Non-profit162$237$132 – $400
System affiliation
Part of a system175$229$132 – $362
Independent20$333$138 – $401

Cash price vs list price

Median list price (chargemaster)$489
Median cash price$237
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

125 hospitals filed a usable inpatient cash price for this code. The median is $274 and the average of the middle 60% is $289; most fall between $148 and $442.

Cash price percentiles, inpatient, across 125 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$144$182$274$439$820

The most expensive tenth of hospitals charges at least 5.7× what the cheapest tenth charges ($144 vs $820).

Of the 128 hospitals that filed this code inpatient, 125 gave a usable cash price; 1 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 2 a list price only.

How complete is this

195 of the 3,956 hospitals with a price file in our corpus (5%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 204 hospitals that filed this code at all gave us
Usable cash price — counted195
Cash price carrying a plausibility flag — shown on the compare tool, excluded here4
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded4
Hospitals that filed this code204

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MECP2 GENE KNOWN VARIANT.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MECP2 gene test for a known family variant (CPT 81303) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81303-mecp2-gene-test-for-a-known-family-variant