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Procedure price report · Pathology

MSH6 gene test for a known family variant

CPT 81299the billing code this page is about

A test that looks only for a specific MSH6 gene change already found in a relative, rather than sequencing the whole gene.

Hospitals typically charge $440 cash for this outpatient procedure — the median across 385 hospitals that filed a usable cash price; the average of the middle 60% is $459. Most fall between $231 and $827 (20th–80th percentile).

Hospitals
385
States
37
Filings dated
Jul 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 385 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$166$296$440$711$1,204

The most expensive tenth of hospitals charges at least 7.2× what the cheapest tenth charges ($166 vs $1,204).

How the prices are spread

$115 – $154: 16 hospitals$115$154 – $207: 18 hospitals$207 – $277: 32 hospitals$207$277 – $372: 85 hospitals$372 – $499: 59 hospitals$372$499 – $670: 47 hospitals$670 – $899: 37 hospitals$670$899 – $1,206: 34 hospitals$1,206 – $1,619: 9 hospitals$1,206$1,619 – $2,172: 10 hospitals$1,619median $440price bands are equal on a log scale
Hospitals per price band (347 of 385 — the bands cover the 5th to 95th percentile)
FromToHospitals
$115$15416
$154$20718
$207$27732
$277$37285
$372$49959
$499$67047
$670$89937
$899$1,20634
$1,206$1,6199
$1,619$2,17210

By state

The median cash price in each state, against the national median of $440.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: median $402 across 18 hospitalsWA$402Idaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 2 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $440 across 12 hospitalsMN$440Illinois: median $711 across 21 hospitalsIL$711Wisconsin: median $519 across 17 hospitalsWI$519Michigan: median $442 across 18 hospitalsMI$442New York: median $308 across 16 hospitalsNY$308Massachusetts: 3 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 7 hospitals filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $296 across 12 hospitalsIA$296Indiana: median $385 across 25 hospitalsIN$385Ohio: median $827 across 19 hospitalsOH$827Pennsylvania: median $150 across 19 hospitalsPA$150New Jersey: median $339 across 29 hospitalsNJ$339Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $1,120 across 21 hospitalsCA$1,120Utah: no hospital in the corpus filed a usable priceUTColorado: 5 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 4 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 8 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $2,172 across 10 hospitalsKY$2,172West Virginia: 2 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $216 across 25 hospitalsVA$216Maryland: 1 hospital filed a usable price — fewer than 10, so no figureMDDelaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $207 across 20 hospitalsTN$207North Carolina: 3 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: median $306 across 16 hospitalsOK$306Louisiana: 4 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 6 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: no hospital in the corpus filed a usable priceALGeorgia: 4 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $370 across 22 hospitalsTX$370Florida: 2 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $440. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Kentucky KY10$2,172+394%$379 – $2,172
California CA21$1,120+155%$1,120 – $1,120
Ohio OH19$827+88%$612 – $827
Illinois IL21$711+62%$711 – $3,028
Wisconsin WI17$519+18%$450 – $519
Michigan MI18$4420%$425 – $476
Minnesota MN12$4400%$440 – $445
Washington WA18$402−9%$196 – $911
Indiana IN25$385−13%$146 – $589
Texas TX22$370−16%$370 – $750
New Jersey NJ29$339−23%$308 – $601
New York NY16$308−30%$308 – $308
Oklahoma OK16$306−30%$166 – $556
Iowa IA12$296−33%$296 – $296
Virginia VA25$216−51%$207 – $513
Tennessee TN20$207−53%$110 – $2,932
Pennsylvania PA19$150−66%$109 – $462
Missouri MO8not enough hospitals filed a usable price
Oregon OR7not enough hospitals filed a usable price
Mississippi MS6not enough hospitals filed a usable price
Colorado CO5not enough hospitals filed a usable price
Georgia GA4not enough hospitals filed a usable price
Louisiana LA4not enough hospitals filed a usable price
Nebraska NE4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
Massachusetts MA3not enough hospitals filed a usable price
North Carolina NC3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Florida FL2not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
North Dakota ND2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
West Virginia WV2not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
Maryland MD1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $440.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care312$370$216 – $894
Children’s6fewer than 20 hospitals
Critical access65$513$436 – $748
Ownership
For-profit20$476$314 – $2,488
Government35$379$260 – $820
Non-profit328$440$216 – $816
System affiliation
Part of a system361$440$216 – $827
Independent24$388$308 – $924

Cash price vs list price

Median list price (chargemaster)$883
Median cash price$440
Cash as a share of list, median hospital56%

At the typical hospital, asking for the cash price cuts the list price by about 44%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

264 hospitals filed a usable inpatient cash price for this code. The median is $379 and the average of the middle 60% is $427; most fall between $207 and $894.

Cash price percentiles, inpatient, across 264 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$138$216$379$770$1,120

The most expensive tenth of hospitals charges at least 8.1× what the cheapest tenth charges ($138 vs $1,120).

Of the 278 hospitals that filed this code inpatient, 264 gave a usable cash price; 2 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 12 a list price only.

How complete is this

385 of the 3,956 hospitals with a price file in our corpus (10%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 419 hospitals that filed this code at all gave us
Usable cash price — counted385
Cash price carrying a plausibility flag — shown on the compare tool, excluded here22
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded11
Hospitals that filed this code419

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MSH6 GENE KNOWN VARIANTS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MSH6 gene test for a known family variant (CPT 81299) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81299-msh6-gene-test-for-a-known-family-variant