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Procedure price report · Pathology

MSH6 gene test, full gene sequencing

CPT 81298the billing code this page is about

A test that reads the entire coding sequence of the MSH6 gene to look for changes linked to Lynch syndrome and related cancer risk.

Hospitals typically charge $747 cash for this outpatient procedure — the median across 826 hospitals that filed a usable cash price; the average of the middle 60% is $847. Most fall between $370 and $1,467 (20th–80th percentile).

Hospitals
826
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 826 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$245$443$747$1,339$2,246

The most expensive tenth of hospitals charges at least 9.2× what the cheapest tenth charges ($245 vs $2,246).

How the prices are spread

$140 – $190: 24 hospitals$140$190 – $258: 28 hospitals$258 – $350: 62 hospitals$258$350 – $475: 64 hospitals$475 – $645: 144 hospitals$475$645 – $876: 95 hospitals$876 – $1,189: 119 hospitals$876$1,189 – $1,613: 116 hospitals$1,613 – $2,190: 45 hospitals$1,613$2,190 – $2,973: 47 hospitals$2,190median $747price bands are equal on a log scale
Hospitals per price band (744 of 826 — the bands cover the 5th to 95th percentile)
FromToHospitals
$140$19024
$190$25828
$258$35062
$350$47564
$475$645144
$645$87695
$876$1,189119
$1,189$1,613116
$1,613$2,19045
$2,190$2,97347

By state

The median cash price in each state, against the national median of $747.

Alaska: 5 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 1 hospital filed a usable price — fewer than 10, so no figureMEVermont: 3 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 3 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $813 across 36 hospitalsWA$813Idaho: 4 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 6 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $1,184 across 12 hospitalsND$1,184Minnesota: median $36 across 15 hospitalsMN$36Illinois: median $1,294 across 43 hospitalsIL$1,294Wisconsin: median $1,075 across 34 hospitalsWI$1,075Michigan: median $795 across 13 hospitalsMI$795New York: median $770 across 37 hospitalsNY$770Massachusetts: median $1,355 across 25 hospitalsMA$1,355Oregon: median $514 across 14 hospitalsOR$514Nevada: 7 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 3 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $616 across 16 hospitalsIA$616Indiana: median $691 across 36 hospitalsIN$691Ohio: median $1,379 across 41 hospitalsOH$1,379Pennsylvania: median $746 across 43 hospitalsPA$746New Jersey: median $706 across 37 hospitalsNJ$706Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 2 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $1,467 across 31 hospitalsCA$1,467Utah: median $1,108 across 23 hospitalsUT$1,108Colorado: median $673 across 30 hospitalsCO$673Nebraska: 6 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $799 across 10 hospitalsMO$799Kentucky: median $608 across 19 hospitalsKY$608West Virginia: 6 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $2,599 across 17 hospitalsVA$2,599Maryland: median $512 across 17 hospitalsMD$512Delaware: 2 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 8 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $961 across 13 hospitalsKS$961Arkansas: 7 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $2,599 across 15 hospitalsTN$2,599North Carolina: median $988 across 17 hospitalsNC$988South Carolina: median $1,057 across 11 hospitalsSC$1,057Oklahoma: median $506 across 16 hospitalsOK$506Louisiana: median $293 across 17 hospitalsLA$293Mississippi: median $309 across 12 hospitalsMS$309Alabama: 3 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $521 across 13 hospitalsGA$521Hawaii: 3 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $276 across 56 hospitalsTX$276Florida: median $1,130 across 30 hospitalsFL$1,130
Cash price by state, most expensive first. National median $747. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Tennessee TN15$2,599+248%$293 – $2,599
Virginia VA17$2,599+248%$564 – $6,174
California CA31$1,467+96%$188 – $1,467
Ohio OH41$1,379+85%$788 – $1,708
Massachusetts MA25$1,355+81%$765 – $2,259
Illinois IL43$1,294+73%$692 – $1,605
North Dakota ND12$1,184+59%$700 – $1,898
Florida FL30$1,130+51%$80 – $2,160
Utah UT23$1,108+48%$1,108 – $1,303
Wisconsin WI34$1,075+44%$36 – $5,157
South Carolina SC11$1,057+42%$476 – $1,057
North Carolina NC17$988+32%$357 – $1,214
Kansas KS13$961+29%$424 – $2,047
Washington WA36$813+9%$575 – $1,388
Missouri MO10$799+7%$490 – $1,188
Michigan MI13$795+6%$148 – $886
New York NY37$770+3%$642 – $1,127
Pennsylvania PA43$7460%$330 – $1,609
New Jersey NJ37$706−5%$642 – $2,670
Indiana IN36$691−8%$479 – $1,145
Colorado CO30$673−10%$280 – $916
Iowa IA16$616−18%$420 – $616
Kentucky KY19$608−19%$437 – $1,662
Georgia GA13$521−30%$444 – $1,672
Oregon OR14$514−31%$514 – $1,715
Maryland MD17$512−32%$294 – $812
Oklahoma OK16$506−32%$347 – $802
Mississippi MS12$309−59%$176 – $629
Louisiana LA17$293−61%$158 – $635
Texas TX56$276−63%$276 – $641
Minnesota MN15$36−95%$35 – $1,366
Arizona AZ8not enough hospitals filed a usable price
Arkansas AR7not enough hospitals filed a usable price
Nevada NV7not enough hospitals filed a usable price
Montana MT6not enough hospitals filed a usable price
Nebraska NE6not enough hospitals filed a usable price
West Virginia WV6not enough hospitals filed a usable price
Alaska AK5not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Idaho ID4not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
Alabama AL3not enough hospitals filed a usable price
Hawaii HI3not enough hospitals filed a usable price
New Hampshire NH3not enough hospitals filed a usable price
Vermont VT3not enough hospitals filed a usable price
Wyoming WY3not enough hospitals filed a usable price
Delaware DE2not enough hospitals filed a usable price
Rhode Island RI2not enough hospitals filed a usable price
Maine ME1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $747.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care660$738$370 – $1,467
Children’s15fewer than 20 hospitals
Critical access146$956$490 – $1,430
Ownership
For-profit57$831$280 – $1,461
Government103$642$342 – $1,214
Non-profit661$770$371 – $1,467
System affiliation
Part of a system706$770$370 – $1,467
Independent120$733$353 – $1,403

Cash price vs list price

Median list price (chargemaster)$1,256
Median cash price$747
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

577 hospitals filed a usable inpatient cash price for this code. The median is $865 and the average of the middle 60% is $903; most fall between $384 and $1,468.

Cash price percentiles, inpatient, across 577 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$276$463$865$1,403$2,551

The most expensive tenth of hospitals charges at least 9.3× what the cheapest tenth charges ($276 vs $2,551).

Of the 677 hospitals that filed this code inpatient, 577 gave a usable cash price; 71 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 29 a list price only.

How complete is this

826 of the 3,956 hospitals with a price file in our corpus (21%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 920 hospitals that filed this code at all gave us
Usable cash price — counted826
Cash price carrying a plausibility flag — shown on the compare tool, excluded here69
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded24
Hospitals that filed this code920

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MSH6 GENE FULL SEQ.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MSH6 gene test, full gene sequencing (CPT 81298) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81298-msh6-gene-test-full-gene-sequencing