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Procedure price report · Pathology

MSH2 gene test for missing or extra gene segments

CPT 81297the billing code this page is about

A test that checks the MSH2 gene for deleted or duplicated pieces rather than single-letter changes, used in Lynch syndrome (hereditary colon cancer) evaluation.

Hospitals typically charge $368 cash for this outpatient procedure — the median across 643 hospitals that filed a usable cash price; the average of the middle 60% is $369. Most fall between $189 and $672 (20th–80th percentile).

Hospitals
643
States
47
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 643 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$122$205$368$568$934

The most expensive tenth of hospitals charges at least 7.7× what the cheapest tenth charges ($122 vs $934).

How the prices are spread

$92 – $122: 34 hospitals$92$122 – $160: 40 hospitals$160 – $211: 59 hospitals$160$211 – $277: 96 hospitals$277 – $365: 61 hospitals$277$365 – $480: 88 hospitals$480 – $631: 92 hospitals$480$631 – $831: 59 hospitals$831 – $1,093: 39 hospitals$831$1,093 – $1,439: 14 hospitals$1,093median $368price bands are equal on a log scale
Hospitals per price band (582 of 643 — the bands cover the 5th to 95th percentile)
FromToHospitals
$92$12234
$122$16040
$160$21159
$211$27796
$277$36561
$365$48088
$480$63192
$631$83159
$831$1,09339
$1,093$1,43914

By state

The median cash price in each state, against the national median of $368.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $324 across 26 hospitalsWA$324Idaho: 3 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: 9 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: 3 hospitals filed a usable price — fewer than 10, so no figureMNIllinois: median $481 across 34 hospitalsIL$481Wisconsin: median $471 across 16 hospitalsWI$471Michigan: median $265 across 13 hospitalsMI$265New York: median $222 across 29 hospitalsNY$222Massachusetts: median $662 across 20 hospitalsMA$662Oregon: median $171 across 15 hospitalsOR$171Nevada: 7 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 3 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $205 across 14 hospitalsIA$205Indiana: median $373 across 33 hospitalsIN$373Ohio: median $347 across 26 hospitalsOH$347Pennsylvania: median $524 across 38 hospitalsPA$524New Jersey: median $235 across 38 hospitalsNJ$235Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 2 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $487 across 32 hospitalsCA$487Utah: median $368 across 23 hospitalsUT$368Colorado: median $280 across 21 hospitalsCO$280Nebraska: 3 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 7 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $203 across 19 hospitalsKY$203West Virginia: 3 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $766 across 16 hospitalsVA$766Maryland: 9 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 6 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $320 across 11 hospitalsKS$320Arkansas: 7 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $119 across 12 hospitalsTN$119North Carolina: 8 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: 8 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: median $457 across 13 hospitalsOK$457Louisiana: median $141 across 13 hospitalsLA$141Mississippi: 7 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 2 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $304 across 10 hospitalsGA$304Hawaii: 3 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $534 across 44 hospitalsTX$534Florida: median $150 across 22 hospitalsFL$150
Cash price by state, most expensive first. National median $368. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Virginia VA16$766+108%$119 – $953
Massachusetts MA20$662+80%$414 – $934
Texas TX44$534+45%$196 – $700
Pennsylvania PA38$524+42%$166 – $2,112
California CA32$487+32%$117 – $487
Illinois IL34$481+31%$293 – $533
Wisconsin WI16$471+28%$471 – $641
Oklahoma OK13$457+24%$132 – $490
Indiana IN33$373+1%$270 – $539
Utah UT23$3680%$368 – $433
Ohio OH26$347−6%$197 – $568
Washington WA26$324−12%$160 – $663
Kansas KS11$320−13%$224 – $685
Georgia GA10$304−17%$147 – $770
Colorado CO21$280−24%$260 – $456
Michigan MI13$265−28%$49 – $294
New Jersey NJ38$235−36%$213 – $1,423
New York NY29$222−40%$213 – $432
Iowa IA14$205−44%$205 – $227
Kentucky KY19$203−45%$116 – $900
Oregon OR15$171−53%$126 – $567
Florida FL22$150−59%$46 – $747
Louisiana LA13$141−62%$75 – $211
Tennessee TN12$119−68%$119 – $119
Maryland MD9not enough hospitals filed a usable price
North Dakota ND9not enough hospitals filed a usable price
North Carolina NC8not enough hospitals filed a usable price
South Carolina SC8not enough hospitals filed a usable price
Arkansas AR7not enough hospitals filed a usable price
Missouri MO7not enough hospitals filed a usable price
Mississippi MS7not enough hospitals filed a usable price
Nevada NV7not enough hospitals filed a usable price
Arizona AZ6not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Hawaii HI3not enough hospitals filed a usable price
Idaho ID3not enough hospitals filed a usable price
Minnesota MN3not enough hospitals filed a usable price
Nebraska NE3not enough hospitals filed a usable price
West Virginia WV3not enough hospitals filed a usable price
Wyoming WY3not enough hospitals filed a usable price
Alabama AL2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
Rhode Island RI2not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $368.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care529$330$187 – $672
Children’s14fewer than 20 hospitals
Critical access97$403$250 – $700
Ownership
For-profit45$441$213 – $700
Government80$265$189 – $533
Non-profit515$371$182 – $700
System affiliation
Part of a system549$374$189 – $700
Independent94$262$186 – $512

Cash price vs list price

Median list price (chargemaster)$640
Median cash price$368
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

432 hospitals filed a usable inpatient cash price for this code. The median is $387 and the average of the middle 60% is $408; most fall between $196 and $700.

Cash price percentiles, inpatient, across 432 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$141$205$387$638$953

The most expensive tenth of hospitals charges at least 6.8× what the cheapest tenth charges ($141 vs $953).

Of the 497 hospitals that filed this code inpatient, 432 gave a usable cash price; 41 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 24 a list price only.

How complete is this

643 of the 3,956 hospitals with a price file in our corpus (16%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 717 hospitals that filed this code at all gave us
Usable cash price — counted643
Cash price carrying a plausibility flag — shown on the compare tool, excluded here50
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded23
Hospitals that filed this code717

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MSH2 GENE DUP/DELETE VARIANT.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MSH2 gene test for missing or extra gene segments (CPT 81297) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81297-msh2-gene-test-for-missing-or-extra-gene-segments