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Procedure price report · Pathology

Full sequencing of the MLH1 gene

CPT 81292the billing code this page is about

A laboratory test on a blood or tissue sample that reads the entire coding sequence of the MLH1 gene, one of the genes involved in Lynch syndrome.

Hospitals typically charge $777 cash for this outpatient procedure — the median across 862 hospitals that filed a usable cash price; the average of the middle 60% is $902. Most fall between $390 and $1,689 (20th–80th percentile).

Hospitals
862
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 862 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$227$459$777$1,497$2,671

The most expensive tenth of hospitals charges at least 12× what the cheapest tenth charges ($227 vs $2,671).

How the prices are spread

$135 – $192: 40 hospitals$135$192 – $272: 22 hospitals$272 – $387: 70 hospitals$272$387 – $551: 101 hospitals$551 – $783: 161 hospitals$551$783 – $1,114: 97 hospitals$1,114 – $1,583: 148 hospitals$1,114$1,583 – $2,251: 61 hospitals$2,251 – $3,201: 68 hospitals$2,251$3,201 – $4,552: 13 hospitals$3,201median $777price bands are equal on a log scale
Hospitals per price band (781 of 862 — the bands cover the 5th to 95th percentile)
FromToHospitals
$135$19240
$192$27222
$272$38770
$387$551101
$551$783161
$783$1,11497
$1,114$1,583148
$1,583$2,25161
$2,251$3,20168
$3,201$4,55213

By state

The median cash price in each state, against the national median of $777.

Alaska: 5 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 1 hospital filed a usable price — fewer than 10, so no figureMEVermont: 3 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $1,030 across 30 hospitalsWA$1,030Idaho: 4 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 5 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $1,175 across 13 hospitalsND$1,175Minnesota: median $354 across 22 hospitalsMN$354Illinois: median $1,294 across 42 hospitalsIL$1,294Wisconsin: median $1,931 across 35 hospitalsWI$1,931Michigan: median $837 across 13 hospitalsMI$837New York: median $810 across 41 hospitalsNY$810Massachusetts: median $1,688 across 22 hospitalsMA$1,688Oregon: median $541 across 14 hospitalsOR$541Nevada: 8 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $648 across 17 hospitalsIA$648Indiana: median $727 across 36 hospitalsIN$727Ohio: median $1,196 across 43 hospitalsOH$1,196Pennsylvania: median $1,222 across 33 hospitalsPA$1,222New Jersey: median $743 across 38 hospitalsNJ$743Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 2 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $1,546 across 32 hospitalsCA$1,546Utah: median $135 across 23 hospitalsUT$135Colorado: median $713 across 18 hospitalsCO$713Nebraska: 6 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $1,250 across 15 hospitalsMO$1,250Kentucky: median $760 across 19 hospitalsKY$760West Virginia: 8 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $4,302 across 18 hospitalsVA$4,302Maryland: median $526 across 17 hospitalsMD$526Delaware: 2 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 8 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $793 across 12 hospitalsKS$793Arkansas: 7 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $2,551 across 19 hospitalsTN$2,551North Carolina: median $1,208 across 18 hospitalsNC$1,208South Carolina: median $1,736 across 12 hospitalsSC$1,736Oklahoma: median $532 across 20 hospitalsOK$532Louisiana: median $679 across 17 hospitalsLA$679Mississippi: median $328 across 13 hospitalsMS$328Alabama: 3 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $652 across 41 hospitalsGA$652Hawaii: 3 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $290 across 61 hospitalsTX$290Florida: median $1,130 across 29 hospitalsFL$1,130
Cash price by state, most expensive first. National median $777. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Virginia VA18$4,302+454%$2,599 – $8,530
Tennessee TN19$2,551+228%$435 – $2,599
Wisconsin WI35$1,931+149%$38 – $5,426
South Carolina SC12$1,736+124%$900 – $2,858
Massachusetts MA22$1,688+117%$966 – $2,299
California CA32$1,546+99%$171 – $1,546
Illinois IL42$1,294+67%$650 – $1,689
Missouri MO15$1,250+61%$490 – $1,342
Pennsylvania PA33$1,222+57%$399 – $5,227
North Carolina NC18$1,208+56%$376 – $1,277
Ohio OH43$1,196+54%$1,065 – $1,658
North Dakota ND13$1,175+51%$851 – $2,026
Florida FL29$1,130+46%$80 – $2,364
Washington WA30$1,030+33%$459 – $1,855
Michigan MI13$837+8%$156 – $932
New York NY41$810+4%$675 – $1,497
Kansas KS12$793+2%$708 – $1,260
Kentucky KY19$760−2%$538 – $2,841
New Jersey NJ38$743−4%$675 – $2,461
Indiana IN36$727−6%$512 – $1,291
Colorado CO18$713−8%$280 – $876
Louisiana LA17$679−13%$469 – $939
Georgia GA41$652−16%$523 – $726
Iowa IA17$648−17%$420 – $648
Oregon OR14$541−30%$541 – $1,792
Oklahoma OK20$532−31%$364 – $802
Maryland MD17$526−32%$381 – $853
Minnesota MN22$354−54%$37 – $408
Mississippi MS13$328−58%$255 – $852
Texas TX61$290−63%$290 – $1,348
Utah UT23$135−83%$135 – $159
Arizona AZ8not enough hospitals filed a usable price
Nevada NV8not enough hospitals filed a usable price
West Virginia WV8not enough hospitals filed a usable price
Arkansas AR7not enough hospitals filed a usable price
Nebraska NE6not enough hospitals filed a usable price
Alaska AK5not enough hospitals filed a usable price
Montana MT5not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Idaho ID4not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price
Alabama AL3not enough hospitals filed a usable price
Hawaii HI3not enough hospitals filed a usable price
Vermont VT3not enough hospitals filed a usable price
Delaware DE2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
Rhode Island RI2not enough hospitals filed a usable price
Maine ME1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $777.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care692$746$399 – $1,736
Children’s15fewer than 20 hospitals
Critical access150$947$383 – $1,847
Ownership
For-profit73$805$365 – $2,027
Government112$719$420 – $1,277
Non-profit672$810$388 – $1,792
System affiliation
Part of a system744$772$381 – $1,823
Independent118$793$399 – $1,403

Cash price vs list price

Median list price (chargemaster)$1,499
Median cash price$777
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

617 hospitals filed a usable inpatient cash price for this code. The median is $794 and the average of the middle 60% is $900; most fall between $370 and $1,653.

Cash price percentiles, inpatient, across 617 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$222$418$794$1,502$2,671

The most expensive tenth of hospitals charges at least 12× what the cheapest tenth charges ($222 vs $2,671).

Of the 714 hospitals that filed this code inpatient, 617 gave a usable cash price; 65 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 32 a list price only.

How complete is this

862 of the 3,956 hospitals with a price file in our corpus (22%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 974 hospitals that filed this code at all gave us
Usable cash price — counted862
Cash price carrying a plausibility flag — shown on the compare tool, excluded here82
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded29
Hospitals that filed this code974

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MLH1 GENE FULL SEQ.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Full sequencing of the MLH1 gene (CPT 81292) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81292-full-sequencing-of-the-mlh1-gene