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Procedure price report · Pathology

MCOLN1 gene test for common mutations

CPT 81290the billing code this page is about

A laboratory test on a blood sample that checks the MCOLN1 gene for the small set of frequently seen changes associated with mucolipidosis type IV.

Hospitals typically charge $123 cash for this outpatient procedure — the median across 509 hospitals that filed a usable cash price; the average of the middle 60% is $122. Most fall between $44 and $280 (20th–80th percentile).

Hospitals
509
States
41
Filings dated
Sep 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 509 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$36$52$123$193$693

The most expensive tenth of hospitals charges at least 19× what the cheapest tenth charges ($36 vs $693).

How the prices are spread

$29 – $42: 58 hospitals$29$42 – $60: 68 hospitals$60 – $86: 48 hospitals$60$86 – $123: 55 hospitals$123 – $176: 105 hospitals$123$176 – $252: 46 hospitals$252 – $361: 30 hospitals$252$361 – $517: 5 hospitals$517 – $741: 24 hospitals$517$741 – $1,062: 20 hospitals$741median $123price bands are equal on a log scale
Hospitals per price band (459 of 509 — the bands cover the 5th to 95th percentile)
FromToHospitals
$29$4258
$42$6068
$60$8648
$86$12355
$123$176105
$176$25246
$252$36130
$361$5175
$517$74124
$741$1,06220

By state

The median cash price in each state, against the national median of $123.

Alaska: no hospital in the corpus filed a usable priceAKMaine: 7 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 1 hospital filed a usable price — fewer than 10, so no figureVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $55 across 17 hospitalsWA$55Idaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureNDMinnesota: median $173 across 10 hospitalsMN$173Illinois: median $140 across 26 hospitalsIL$140Wisconsin: median $160 across 17 hospitalsWI$160Michigan: median $36 across 18 hospitalsMI$36New York: median $69 across 37 hospitalsNY$69Massachusetts: median $170 across 19 hospitalsMA$170Oregon: 3 hospitals filed a usable price — fewer than 10, so no figureORNevada: 4 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $128 across 11 hospitalsIA$128Indiana: median $57 across 25 hospitalsIN$57Ohio: median $328 across 53 hospitalsOH$328Pennsylvania: median $119 across 33 hospitalsPA$119New Jersey: median $43 across 34 hospitalsNJ$43Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $134 across 28 hospitalsCA$134Utah: 2 hospitals filed a usable price — fewer than 10, so no figureUTColorado: 5 hospitals filed a usable price — fewer than 10, so no figureCONebraska: no hospital in the corpus filed a usable priceNEMissouri: 8 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $331 across 16 hospitalsKY$331West Virginia: 3 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: 6 hospitals filed a usable price — fewer than 10, so no figureVAMaryland: median $236 across 10 hospitalsMD$236Delaware: 3 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 4 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 2 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 5 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: no hospital in the corpus filed a usable priceARTennessee: 7 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: median $556 across 19 hospitalsNC$556South Carolina: median $90 across 11 hospitalsSC$90Oklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 4 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 5 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: no hospital in the corpus filed a usable priceGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $163 across 29 hospitalsTX$163Florida: median $80 across 13 hospitalsFL$80
Cash price by state, most expensive first. National median $123. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
North Carolina NC19$556+353%$142 – $649
Kentucky KY16$331+169%$47 – $1,664
Ohio OH53$328+167%$119 – $757
Maryland MD10$236+92%$155 – $321
Minnesota MN10$173+41%$25 – $173
Massachusetts MA19$170+39%$78 – $632
Texas TX29$163+33%$24 – $163
Wisconsin WI17$160+30%$113 – $175
Illinois IL26$140+14%$91 – $158
California CA28$134+9%$35 – $134
Iowa IA11$128+4%$128 – $128
Pennsylvania PA33$119−3%$28 – $1,062
South Carolina SC11$90−27%$90 – $90
Florida FL13$80−35%$39 – $80
New York NY37$69−44%$39 – $221
Indiana IN25$57−54%$35 – $77
Washington WA17$55−55%$45 – $64
New Jersey NJ34$43−65%$39 – $2,148
Michigan MI18$36−70%$31 – $54
Missouri MO8not enough hospitals filed a usable price
Maine ME7not enough hospitals filed a usable price
Tennessee TN7not enough hospitals filed a usable price
Virginia VA6not enough hospitals filed a usable price
Colorado CO5not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Kansas KS5not enough hospitals filed a usable price
Mississippi MS5not enough hospitals filed a usable price
Arizona AZ4not enough hospitals filed a usable price
Louisiana LA4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
Nevada NV4not enough hospitals filed a usable price
Delaware DE3not enough hospitals filed a usable price
Oregon OR3not enough hospitals filed a usable price
West Virginia WV3not enough hospitals filed a usable price
New Mexico NM2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Utah UT2not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
North Dakota ND1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Vermont VT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $123.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care453$124$43 – $285
Children’s10fewer than 20 hospitals
Critical access41$118$63 – $246
Ownership
For-profit26$76$48 – $160
Government46$63$39 – $144
Non-profit432$133$47 – $285
System affiliation
Part of a system463$128$44 – $285
Independent46$81$45 – $144

Cash price vs list price

Median list price (chargemaster)$201
Median cash price$123
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

354 hospitals filed a usable inpatient cash price for this code. The median is $134 and the average of the middle 60% is $140; most fall between $60 and $280.

Cash price percentiles, inpatient, across 354 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$36$73$134$221$693

The most expensive tenth of hospitals charges at least 19× what the cheapest tenth charges ($36 vs $693).

Of the 377 hospitals that filed this code inpatient, 354 gave a usable cash price; 14 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 9 a list price only.

How complete is this

509 of the 3,956 hospitals with a price file in our corpus (13%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 532 hospitals that filed this code at all gave us
Usable cash price — counted509
Cash price carrying a plausibility flag — shown on the compare tool, excluded here16
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded7
Hospitals that filed this code532

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as MCOLN1 GENE.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “MCOLN1 gene test for common mutations (CPT 81290) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81290-mcoln1-gene-test-for-common-mutations