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Procedure price report · Pathology

KRAS gene test for the two most common mutations

CPT 81275the billing code this page is about

A laboratory test on tumor tissue that looks only at KRAS gene positions 12 and 13, the spots most often altered in colorectal, lung, and pancreatic cancers.

Hospitals typically charge $426 cash for this outpatient procedure — the median across 1,834 hospitals that filed a usable cash price; the average of the middle 60% is $445. Most fall between $213 and $823 (20th–80th percentile).

Hospitals
1,834
States
50
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,834 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$143$232$426$698$1,256

The most expensive tenth of hospitals charges at least 8.8× what the cheapest tenth charges ($143 vs $1,256).

How the prices are spread

$104 – $139: 89 hospitals$104$139 – $186: 96 hospitals$186 – $248: 233 hospitals$186$248 – $330: 194 hospitals$330 – $440: 236 hospitals$330$440 – $587: 303 hospitals$587 – $783: 184 hospitals$587$783 – $1,045: 148 hospitals$1,045 – $1,393: 110 hospitals$1,045$1,393 – $1,858: 59 hospitals$1,393median $426price bands are equal on a log scale
Hospitals per price band (1,652 of 1,834 — the bands cover the 5th to 95th percentile)
FromToHospitals
$104$13989
$139$18696
$186$248233
$248$330194
$330$440236
$440$587303
$587$783184
$783$1,045148
$1,045$1,393110
$1,393$1,85859

By state

The median cash price in each state, against the national median of $426.

Alaska: median $286 across 11 hospitalsAK$286Maine: median $351 across 24 hospitalsME$351Vermont: 4 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $515 across 13 hospitalsNH$515Washington: median $532 across 45 hospitalsWA$532Idaho: 8 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 4 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $411 across 53 hospitalsMN$411Illinois: median $536 across 80 hospitalsIL$536Wisconsin: median $474 across 82 hospitalsWI$474Michigan: median $267 across 53 hospitalsMI$267New York: median $472 across 62 hospitalsNY$472Massachusetts: median $567 across 30 hospitalsMA$567Oregon: median $240 across 30 hospitalsOR$240Nevada: 9 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 6 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 3 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $372 across 25 hospitalsIA$372Indiana: median $396 across 69 hospitalsIN$396Ohio: median $539 across 89 hospitalsOH$539Pennsylvania: median $364 across 86 hospitalsPA$364New Jersey: median $222 across 47 hospitalsNJ$222Connecticut: median $536 across 12 hospitalsCT$536Rhode Island: 7 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $346 across 63 hospitalsCA$346Utah: median $1,068 across 26 hospitalsUT$1,068Colorado: median $355 across 34 hospitalsCO$355Nebraska: median $926 across 15 hospitalsNE$926Missouri: median $459 across 52 hospitalsMO$459Kentucky: median $537 across 38 hospitalsKY$537West Virginia: median $102 across 25 hospitalsWV$102Virginia: median $692 across 49 hospitalsVA$692Maryland: median $360 across 32 hospitalsMD$360Delaware: 5 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $585 across 28 hospitalsAZ$585New Mexico: median $349 across 13 hospitalsNM$349Kansas: median $649 across 29 hospitalsKS$649Arkansas: median $422 across 22 hospitalsAR$422Tennessee: median $251 across 35 hospitalsTN$251North Carolina: median $695 across 33 hospitalsNC$695South Carolina: median $486 across 34 hospitalsSC$486Oklahoma: median $406 across 42 hospitalsOK$406Louisiana: median $350 across 29 hospitalsLA$350Mississippi: median $176 across 34 hospitalsMS$176Alabama: median $347 across 16 hospitalsAL$347Georgia: median $283 across 67 hospitalsGA$283Hawaii: 7 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $326 across 155 hospitalsTX$326Florida: median $329 across 94 hospitalsFL$329
Cash price by state, most expensive first. National median $426. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT26$1,068+150%$1,068 – $1,256
Nebraska NE15$926+117%$390 – $1,043
North Carolina NC33$695+63%$168 – $1,083
Virginia VA49$692+62%$445 – $1,168
Kansas KS29$649+52%$206 – $1,330
Arizona AZ28$585+37%$260 – $847
Massachusetts MA30$567+33%$259 – $1,030
Ohio OH89$539+26%$303 – $1,106
Kentucky KY38$537+26%$257 – $580
Illinois IL80$536+26%$339 – $953
Connecticut CT12$536+26%$358 – $842
Washington WA45$532+25%$294 – $599
New Hampshire NH13$515+21%$227 – $937
South Carolina SC34$486+14%$453 – $1,349
Wisconsin WI82$474+11%$260 – $855
New York NY62$472+11%$193 – $842
Missouri MO52$459+8%$287 – $684
Arkansas AR22$422−1%$146 – $553
Minnesota MN53$411−4%$164 – $673
Oklahoma OK42$406−5%$204 – $664
Indiana IN69$396−7%$245 – $574
Iowa IA25$372−13%$186 – $658
Pennsylvania PA86$364−15%$222 – $1,025
Maryland MD32$360−15%$232 – $711
Colorado CO34$355−17%$206 – $1,204
Maine ME24$351−18%$163 – $552
Louisiana LA29$350−18%$103 – $495
New Mexico NM13$349−18%$267 – $462
Alabama AL16$347−19%$254 – $457
California CA63$346−19%$137 – $442
Florida FL94$329−23%$139 – $773
Texas TX155$326−24%$201 – $1,177
Alaska AK11$286−33%$183 – $873
Georgia GA67$283−34%$262 – $754
Michigan MI53$267−37%$112 – $719
Tennessee TN35$251−41%$199 – $1,114
Oregon OR30$240−44%$232 – $439
New Jersey NJ47$222−48%$193 – $441
Mississippi MS34$176−59%$82 – $802
West Virginia WV25$102−76%$76 – $848
Nevada NV9not enough hospitals filed a usable price
Idaho ID8not enough hospitals filed a usable price
Hawaii HI7not enough hospitals filed a usable price
Rhode Island RI7not enough hospitals filed a usable price
Wyoming WY6not enough hospitals filed a usable price
Delaware DE5not enough hospitals filed a usable price
North Dakota ND5not enough hospitals filed a usable price
Montana MT4not enough hospitals filed a usable price
Vermont VT4not enough hospitals filed a usable price
South Dakota SD3not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $426.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,497$411$205 – $819
Children’s20$401$146 – $744
Critical access310$530$260 – $843
Ownership
For-profit275$580$230 – $1,279
Government227$361$193 – $695
Non-profit1,325$426$213 – $774
System affiliation
Part of a system1,602$439$213 – $837
Independent232$399$209 – $789

Cash price vs list price

Median list price (chargemaster)$747
Median cash price$426
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,306 hospitals filed a usable inpatient cash price for this code. The median is $426 and the average of the middle 60% is $451; most fall between $227 and $822.

Cash price percentiles, inpatient, across 1,306 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$150$241$426$724$1,254

The most expensive tenth of hospitals charges at least 8.4× what the cheapest tenth charges ($150 vs $1,254).

Of the 1,432 hospitals that filed this code inpatient, 1,306 gave a usable cash price; 82 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 44 a list price only.

How complete is this

1,834 of the 3,956 hospitals with a price file in our corpus (46%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,981 hospitals that filed this code at all gave us
Usable cash price — counted1,834
Cash price carrying a plausibility flag — shown on the compare tool, excluded here93
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded52
Hospitals that filed this code1,981

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Kras Ngs Exon 2.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “KRAS gene test for the two most common mutations (CPT 81275) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81275-kras-gene-test-for-the-two-most-common-mutations