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Procedure price report · Pathology

Hereditary hemochromatosis gene test for common variants

CPT 81256the billing code this page is about

A laboratory test that checks the HFE gene for the common variants linked to iron overload.

Hospitals typically charge $244 cash for this outpatient procedure — the median across 2,946 hospitals that filed a usable cash price; the average of the middle 60% is $250. Most fall between $101 and $458 (20th–80th percentile).

Hospitals
2,946
States
50
Filings dated
Mar 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 2,946 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$68$121$244$404$603

The most expensive tenth of hospitals charges at least 8.9× what the cheapest tenth charges ($68 vs $603).

How the prices are spread

$50 – $66: 133 hospitals$50$66 – $87: 192 hospitals$87 – $115: 224 hospitals$87$115 – $152: 309 hospitals$152 – $201: 252 hospitals$152$201 – $266: 344 hospitals$266 – $351: 428 hospitals$266$351 – $464: 361 hospitals$464 – $613: 268 hospitals$464$613 – $810: 142 hospitals$613median $244price bands are equal on a log scale
Hospitals per price band (2,653 of 2,946 — the bands cover the 5th to 95th percentile)
FromToHospitals
$50$66133
$66$87192
$87$115224
$115$152309
$152$201252
$201$266344
$266$351428
$351$464361
$464$613268
$613$810142

By state

The median cash price in each state, against the national median of $244.

Alaska: median $409 across 16 hospitalsAK$409Maine: median $139 across 28 hospitalsME$139Vermont: median $235 across 13 hospitalsVT$235New Hampshire: median $315 across 24 hospitalsNH$315Washington: median $265 across 70 hospitalsWA$265Idaho: median $168 across 22 hospitalsID$168Montana: median $270 across 21 hospitalsMT$270North Dakota: median $247 across 26 hospitalsND$247Minnesota: median $228 across 92 hospitalsMN$228Illinois: median $378 across 132 hospitalsIL$378Wisconsin: median $403 across 99 hospitalsWI$403Michigan: median $132 across 85 hospitalsMI$132New York: median $173 across 101 hospitalsNY$173Massachusetts: median $316 across 50 hospitalsMA$316Oregon: median $199 across 37 hospitalsOR$199Nevada: median $197 across 19 hospitalsNV$197Wyoming: median $277 across 16 hospitalsWY$277South Dakota: median $384 across 24 hospitalsSD$384Iowa: median $290 across 76 hospitalsIA$290Indiana: median $281 across 93 hospitalsIN$281Ohio: median $286 across 134 hospitalsOH$286Pennsylvania: median $326 across 115 hospitalsPA$326New Jersey: median $72 across 54 hospitalsNJ$72Connecticut: median $212 across 20 hospitalsCT$212Rhode Island: median $199 across 10 hospitalsRI$199California: median $105 across 111 hospitalsCA$105Utah: median $659 across 37 hospitalsUT$659Colorado: median $246 across 63 hospitalsCO$246Nebraska: median $345 across 66 hospitalsNE$345Missouri: median $296 across 71 hospitalsMO$296Kentucky: median $318 across 63 hospitalsKY$318West Virginia: median $194 across 40 hospitalsWV$194Virginia: median $244 across 69 hospitalsVA$244Maryland: median $152 across 37 hospitalsMD$152Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $300 across 37 hospitalsAZ$300New Mexico: median $362 across 17 hospitalsNM$362Kansas: median $365 across 71 hospitalsKS$365Arkansas: median $120 across 36 hospitalsAR$120Tennessee: median $140 across 77 hospitalsTN$140North Carolina: median $186 across 84 hospitalsNC$186South Carolina: median $419 across 44 hospitalsSC$419Oklahoma: median $227 across 58 hospitalsOK$227Louisiana: median $159 across 48 hospitalsLA$159Mississippi: median $88 across 48 hospitalsMS$88Alabama: median $204 across 36 hospitalsAL$204Georgia: median $256 across 98 hospitalsGA$256Hawaii: median $182 across 14 hospitalsHI$182Texas: median $235 across 201 hospitalsTX$235Florida: median $86 across 136 hospitalsFL$86
Cash price by state, most expensive first. National median $244. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT37$659+170%$235 – $775
South Carolina SC44$419+71%$182 – $538
Alaska AK16$409+67%$265 – $710
Wisconsin WI99$403+65%$252 – $502
South Dakota SD24$384+57%$201 – $745
Illinois IL132$378+55%$210 – $571
Kansas KS71$365+50%$177 – $569
New Mexico NM17$362+48%$134 – $810
Nebraska NE66$345+41%$145 – $522
Pennsylvania PA115$326+34%$84 – $556
Kentucky KY63$318+30%$107 – $461
Massachusetts MA50$316+29%$190 – $380
New Hampshire NH24$315+29%$201 – $448
Arizona AZ37$300+23%$88 – $549
Missouri MO71$296+21%$141 – $426
Iowa IA76$290+19%$128 – $436
Ohio OH134$286+17%$156 – $335
Indiana IN93$281+15%$128 – $482
Wyoming WY16$277+13%$169 – $390
Montana MT21$270+10%$178 – $530
Washington WA70$265+9%$181 – $399
Georgia GA98$256+5%$139 – $379
North Dakota ND26$247+1%$114 – $430
Colorado CO63$246+1%$103 – $428
Virginia VA69$2440%$109 – $732
Texas TX201$235−4%$110 – $554
Vermont VT13$235−4%$183 – $442
Minnesota MN92$228−7%$125 – $403
Oklahoma OK58$227−7%$121 – $396
Connecticut CT20$212−13%$130 – $313
Alabama AL36$204−16%$97 – $465
Rhode Island RI10$199−19%$152 – $407
Oregon OR37$199−19%$115 – $332
Nevada NV19$197−19%$65 – $526
West Virginia WV40$194−21%$85 – $394
North Carolina NC84$186−24%$98 – $478
Hawaii HI14$182−26%$124 – $506
New York NY101$173−29%$81 – $358
Idaho ID22$168−31%$119 – $256
Louisiana LA48$159−35%$92 – $412
Maryland MD37$152−38%$102 – $313
Tennessee TN77$140−43%$112 – $257
Maine ME28$139−43%$91 – $332
Michigan MI85$132−46%$56 – $308
Arkansas AR36$120−51%$48 – $258
California CA111$105−57%$61 – $266
Mississippi MS48$88−64%$43 – $252
Florida FL136$86−65%$61 – $206
New Jersey NJ54$72−71%$65 – $221
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $244.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,093$223$90 – $445
Children’s35$204$69 – $378
Critical access808$289$141 – $478
Ownership
For-profit387$225$75 – $549
Government527$255$119 – $466
Non-profit2,022$244$100 – $440
System affiliation
Part of a system2,407$244$96 – $458
Independent539$243$122 – $439

Cash price vs list price

Median list price (chargemaster)$394
Median cash price$244
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

2,014 hospitals filed a usable inpatient cash price for this code. The median is $256 and the average of the middle 60% is $258; most fall between $115 and $461.

Cash price percentiles, inpatient, across 2,014 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$76$129$256$406$569

The most expensive tenth of hospitals charges at least 7.5× what the cheapest tenth charges ($76 vs $569).

Of the 2,221 hospitals that filed this code inpatient, 2,014 gave a usable cash price; 110 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 97 a list price only.

How complete is this

2,946 of the 3,956 hospitals with a price file in our corpus (74%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,207 hospitals that filed this code at all gave us
Usable cash price — counted2,946
Cash price carrying a plausibility flag — shown on the compare tool, excluded here149
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded111
Hospitals that filed this code3,207

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Hfe Hemochromatosis (Hemc).

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Hereditary hemochromatosis gene test for common variants (CPT 81256) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81256-hereditary-hemochromatosis-gene-test-for-common-variants