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Procedure price report · Pathology

GBA gene test for common Gaucher disease variants

CPT 81251the billing code this page is about

Laboratory analysis of the GBA gene for common variants associated with Gaucher disease. Covers one test on one sample.

Hospitals typically charge $161 cash for this outpatient procedure — the median across 667 hospitals that filed a usable cash price; the average of the middle 60% is $181. Most fall between $57 and $406 (20th–80th percentile).

Hospitals
667
States
46
Filings dated
Aug 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 667 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$47$67$161$332$675

The most expensive tenth of hospitals charges at least 14× what the cheapest tenth charges ($47 vs $675).

How the prices are spread

$35 – $51: 73 hospitals$35$51 – $75: 86 hospitals$75 – $111: 68 hospitals$75$111 – $163: 88 hospitals$163 – $240: 86 hospitals$163$240 – $354: 80 hospitals$354 – $521: 39 hospitals$354$521 – $767: 57 hospitals$767 – $1,130: 13 hospitals$767$1,130 – $1,664: 16 hospitals$1,130median $161price bands are equal on a log scale
Hospitals per price band (606 of 667 — the bands cover the 5th to 95th percentile)
FromToHospitals
$35$5173
$51$7586
$75$11168
$111$16388
$163$24086
$240$35480
$354$52139
$521$76757
$767$1,13013
$1,130$1,66416

By state

The median cash price in each state, against the national median of $161.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: 7 hospitals filed a usable price — fewer than 10, so no figureMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 5 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $71 across 18 hospitalsWA$71Idaho: 2 hospitals filed a usable price — fewer than 10, so no figureIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureNDMinnesota: median $91 across 17 hospitalsMN$91Illinois: median $140 across 26 hospitalsIL$140Wisconsin: median $160 across 18 hospitalsWI$160Michigan: median $36 across 20 hospitalsMI$36New York: median $73 across 38 hospitalsNY$73Massachusetts: median $230 across 26 hospitalsMA$230Oregon: 7 hospitals filed a usable price — fewer than 10, so no figureORNevada: 5 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $128 across 12 hospitalsIA$128Indiana: median $69 across 28 hospitalsIN$69Ohio: median $327 across 60 hospitalsOH$327Pennsylvania: median $226 across 40 hospitalsPA$226New Jersey: median $52 across 37 hospitalsNJ$52Connecticut: 7 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 2 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $161 across 37 hospitalsCA$161Utah: median $2,131 across 25 hospitalsUT$2,131Colorado: 8 hospitals filed a usable price — fewer than 10, so no figureCONebraska: no hospital in the corpus filed a usable priceNEMissouri: median $232 across 15 hospitalsMO$232Kentucky: median $325 across 18 hospitalsKY$325West Virginia: 5 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $397 across 14 hospitalsVA$397Maryland: median $312 across 17 hospitalsMD$312Delaware: 4 hospitals filed a usable price — fewer than 10, so no figureDEArizona: 5 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 3 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 6 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 8 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $121 across 16 hospitalsTN$121North Carolina: median $556 across 19 hospitalsNC$556South Carolina: median $199 across 11 hospitalsSC$199Oklahoma: 5 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 7 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 9 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 4 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: 3 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: 1 hospital filed a usable price — fewer than 10, so no figureHITexas: median $292 across 34 hospitalsTX$292Florida: median $80 across 15 hospitalsFL$80
Cash price by state, most expensive first. National median $161. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT25$2,131+1226%$2,131 – $2,507
North Carolina NC19$556+246%$142 – $649
Virginia VA14$397+147%$397 – $539
Ohio OH60$327+103%$202 – $613
Kentucky KY18$325+102%$97 – $1,664
Maryland MD17$312+94%$136 – $405
Texas TX34$292+82%$29 – $292
Missouri MO15$232+44%$223 – $407
Massachusetts MA26$230+43%$147 – $407
Pennsylvania PA40$226+41%$54 – $602
South Carolina SC11$199+24%$199 – $199
California CA37$1610%$47 – $161
Wisconsin WI18$1600%$136 – $164
Illinois IL26$140−13%$109 – $166
Iowa IA12$128−20%$128 – $128
Tennessee TN16$121−25%$61 – $167
Minnesota MN17$91−44%$39 – $173
Florida FL15$80−50%$47 – $155
New York NY38$73−55%$47 – $297
Washington WA18$71−56%$66 – $103
Indiana IN28$69−57%$60 – $108
New Jersey NJ37$52−68%$47 – $933
Michigan MI20$36−77%$31 – $65
Mississippi MS9not enough hospitals filed a usable price
Arkansas AR8not enough hospitals filed a usable price
Colorado CO8not enough hospitals filed a usable price
Connecticut CT7not enough hospitals filed a usable price
Louisiana LA7not enough hospitals filed a usable price
Maine ME7not enough hospitals filed a usable price
Oregon OR7not enough hospitals filed a usable price
Kansas KS6not enough hospitals filed a usable price
Arizona AZ5not enough hospitals filed a usable price
New Hampshire NH5not enough hospitals filed a usable price
Nevada NV5not enough hospitals filed a usable price
Oklahoma OK5not enough hospitals filed a usable price
West Virginia WV5not enough hospitals filed a usable price
Alabama AL4not enough hospitals filed a usable price
Delaware DE4not enough hospitals filed a usable price
Georgia GA3not enough hospitals filed a usable price
New Mexico NM3not enough hospitals filed a usable price
Idaho ID2not enough hospitals filed a usable price
Rhode Island RI2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Hawaii HI1not enough hospitals filed a usable price
North Dakota ND1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $161.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care575$160$54 – $397
Children’s19fewer than 20 hospitals
Critical access67$265$91 – $504
Ownership
For-profit45$142$59 – $340
Government56$86$47 – $190
Non-profit560$164$61 – $457
System affiliation
Part of a system595$161$60 – $408
Independent72$133$54 – $349

Cash price vs list price

Median list price (chargemaster)$287
Median cash price$161
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

466 hospitals filed a usable inpatient cash price for this code. The median is $173 and the average of the middle 60% is $201; most fall between $83 and $397.

Cash price percentiles, inpatient, across 466 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$47$94$173$332$676

The most expensive tenth of hospitals charges at least 14× what the cheapest tenth charges ($47 vs $676).

Of the 515 hospitals that filed this code inpatient, 466 gave a usable cash price; 26 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 23 a list price only.

How complete is this

667 of the 3,956 hospitals with a price file in our corpus (17%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 726 hospitals that filed this code at all gave us
Usable cash price — counted667
Cash price carrying a plausibility flag — shown on the compare tool, excluded here32
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded27
Hospitals that filed this code726

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as GBA GENE.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “GBA gene test for common Gaucher disease variants (CPT 81251) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81251-gba-gene-test-for-common-gaucher-disease-variants