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Procedure price report · Pathology

G6PC gene test for common variants

CPT 81250the billing code this page is about

Laboratory analysis of the G6PC gene for common variants linked to glycogen storage disease type 1a. Covers one test on one sample.

Hospitals typically charge $126 cash for this outpatient procedure — the median across 440 hospitals that filed a usable cash price; the average of the middle 60% is $131. Most fall between $58 and $263 (20th–80th percentile).

Hospitals
440
States
37
Filings dated
Dec 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 440 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$45$64$126$226$556

The most expensive tenth of hospitals charges at least 12× what the cheapest tenth charges ($45 vs $556).

How the prices are spread

$35 – $47: 24 hospitals$35$47 – $65: 68 hospitals$65 – $89: 56 hospitals$65$89 – $122: 40 hospitals$122 – $168: 81 hospitals$122$168 – $230: 43 hospitals$230 – $315: 25 hospitals$230$315 – $431: 26 hospitals$431 – $591: 13 hospitals$431$591 – $811: 21 hospitals$591median $126price bands are equal on a log scale
Hospitals per price band (397 of 440 — the bands cover the 5th to 95th percentile)
FromToHospitals
$35$4724
$47$6568
$65$8956
$89$12240
$122$16881
$168$23043
$230$31525
$315$43126
$431$59113
$591$81121

By state

The median cash price in each state, against the national median of $126.

Alaska: no hospital in the corpus filed a usable priceAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 3 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $61 across 10 hospitalsWA$61Idaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $112 across 20 hospitalsMN$112Illinois: median $140 across 25 hospitalsIL$140Wisconsin: median $195 across 17 hospitalsWI$195Michigan: median $31 across 13 hospitalsMI$31New York: median $58 across 16 hospitalsNY$58Massachusetts: median $379 across 15 hospitalsMA$379Oregon: no hospital in the corpus filed a usable priceORNevada: 5 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $118 across 11 hospitalsIA$118Indiana: median $85 across 14 hospitalsIN$85Ohio: median $123 across 39 hospitalsOH$123Pennsylvania: median $734 across 31 hospitalsPA$734New Jersey: median $64 across 34 hospitalsNJ$64Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 2 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $162 across 29 hospitalsCA$162Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: median $88 across 10 hospitalsCO$88Nebraska: no hospital in the corpus filed a usable priceNEMissouri: 2 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $332 across 12 hospitalsKY$332West Virginia: 1 hospital filed a usable price — fewer than 10, so no figureWVVirginia: 6 hospitals filed a usable price — fewer than 10, so no figureVAMaryland: 4 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 4 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 3 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 4 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $155 across 10 hospitalsTN$155North Carolina: median $649 across 16 hospitalsNC$649South Carolina: no hospital in the corpus filed a usable priceSCOklahoma: median $82 across 17 hospitalsOK$82Louisiana: 4 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 2 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 4 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: no hospital in the corpus filed a usable priceGAHawaii: 1 hospital filed a usable price — fewer than 10, so no figureHITexas: median $141 across 31 hospitalsTX$141Florida: median $105 across 18 hospitalsFL$105
Cash price by state, most expensive first. National median $126. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Pennsylvania PA31$734+482%$88 – $1,399
North Carolina NC16$649+414%$206 – $649
Massachusetts MA15$379+200%$130 – $528
Kentucky KY12$332+163%$97 – $332
Wisconsin WI17$195+55%$169 – $195
California CA29$162+29%$35 – $162
Tennessee TN10$155+23%$126 – $158
Texas TX31$141+12%$36 – $154
Illinois IL25$140+11%$134 – $140
Ohio OH39$123−2%$87 – $263
Iowa IA11$118−7%$118 – $118
Minnesota MN20$112−11%$34 – $200
Florida FL18$105−17%$41 – $391
Colorado CO10$88−30%$88 – $168
Indiana IN14$85−32%$75 – $121
Oklahoma OK17$82−35%$50 – $82
New Jersey NJ34$64−49%$58 – $1,155
Washington WA10$61−52%$56 – $88
New York NY16$58−54%$58 – $73
Michigan MI13$31−76%$31 – $81
Virginia VA6not enough hospitals filed a usable price
Nevada NV5not enough hospitals filed a usable price
Alabama AL4not enough hospitals filed a usable price
Arizona AZ4not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Kansas KS4not enough hospitals filed a usable price
Louisiana LA4not enough hospitals filed a usable price
Maryland MD4not enough hospitals filed a usable price
New Hampshire NH3not enough hospitals filed a usable price
New Mexico NM3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Missouri MO2not enough hospitals filed a usable price
Mississippi MS2not enough hospitals filed a usable price
Rhode Island RI2not enough hospitals filed a usable price
Hawaii HI1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price
West Virginia WV1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $126.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care392$131$58 – $310
Children’s11fewer than 20 hospitals
Critical access34$121$84 – $225
Ownership
For-profit30$126$58 – $310
Government35$88$58 – $168
Non-profit372$134$62 – $264
System affiliation
Part of a system404$134$58 – $289
Independent36$90$58 – $182

Cash price vs list price

Median list price (chargemaster)$280
Median cash price$126
Cash as a share of list, median hospital56%

At the typical hospital, asking for the cash price cuts the list price by about 44%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

306 hospitals filed a usable inpatient cash price for this code. The median is $140 and the average of the middle 60% is $150; most fall between $82 and $263.

Cash price percentiles, inpatient, across 306 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$36$87$140$224$509

The most expensive tenth of hospitals charges at least 14× what the cheapest tenth charges ($36 vs $509).

Of the 334 hospitals that filed this code inpatient, 306 gave a usable cash price; 18 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 10 a list price only.

How complete is this

440 of the 3,956 hospitals with a price file in our corpus (11%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 469 hospitals that filed this code at all gave us
Usable cash price — counted440
Cash price carrying a plausibility flag — shown on the compare tool, excluded here20
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded8
Hospitals that filed this code469

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as G6PC GENE.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “G6PC gene test for common variants (CPT 81250) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81250-g6pc-gene-test-for-common-variants