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Procedure price report · Pathology

EZH2 gene test for common variants

CPT 81237the billing code this page is about

Laboratory analysis of the EZH2 gene limited to common variant sites rather than the whole gene. Covers one test on one sample.

Hospitals typically charge $288 cash for this outpatient procedure — the median across 161 hospitals that filed a usable cash price; the average of the middle 60% is $274. Most fall between $175 and $403 (20th–80th percentile).

Hospitals
161
States
26
Filings dated
Dec 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 161 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$125$175$288$403$566

The most expensive tenth of hospitals charges at least 4.5× what the cheapest tenth charges ($125 vs $566).

How the prices are spread

$73 – $92: 1 hospitals$73$92 – $117: 7 hospitals$117 – $147: 6 hospitals$117$147 – $186: 28 hospitals$186 – $235: 20 hospitals$186$235 – $296: 18 hospitals$296 – $374: 21 hospitals$296$374 – $472: 29 hospitals$472 – $596: 11 hospitals$472$596 – $752: 5 hospitals$596median $288price bands are equal on a log scale
Hospitals per price band (146 of 161 — the bands cover the 5th to 95th percentile)
FromToHospitals
$73$921
$92$1177
$117$1476
$147$18628
$186$23520
$235$29618
$296$37421
$374$47229
$472$59611
$596$7525

By state

The median cash price in each state, against the national median of $288.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: 2 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: 7 hospitals filed a usable price — fewer than 10, so no figureMNIllinois: 5 hospitals filed a usable price — fewer than 10, so no figureILWisconsin: no hospital in the corpus filed a usable priceWIMichigan: 4 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $175 across 18 hospitalsNY$175Massachusetts: 6 hospitals filed a usable price — fewer than 10, so no figureMAOregon: no hospital in the corpus filed a usable priceORNevada: 1 hospital filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: 2 hospitals filed a usable price — fewer than 10, so no figureIAIndiana: no hospital in the corpus filed a usable priceINOhio: median $329 across 18 hospitalsOH$329Pennsylvania: median $60 across 12 hospitalsPA$60New Jersey: median $193 across 29 hospitalsNJ$193Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $403 across 20 hospitalsCA$403Utah: no hospital in the corpus filed a usable priceUTColorado: 1 hospital filed a usable price — fewer than 10, so no figureCONebraska: no hospital in the corpus filed a usable priceNEMissouri: 2 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: no hospital in the corpus filed a usable priceKYWest Virginia: 2 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: 4 hospitals filed a usable price — fewer than 10, so no figureVAMaryland: 8 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 1 hospital filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: no hospital in the corpus filed a usable priceARTennessee: 1 hospital filed a usable price — fewer than 10, so no figureTNNorth Carolina: no hospital in the corpus filed a usable priceNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 2 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: no hospital in the corpus filed a usable priceMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: 9 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: no hospital in the corpus filed a usable priceHITexas: no hospital in the corpus filed a usable priceTXFlorida: 2 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $288. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA20$403+40%$403 – $403
Ohio OH18$329+14%$329 – $329
New Jersey NJ29$193−33%$175 – $307
New York NY18$175−39%$175 – $231
Pennsylvania PA12$60−79%$55 – $263
Georgia GA9not enough hospitals filed a usable price
Maryland MD8not enough hospitals filed a usable price
Minnesota MN7not enough hospitals filed a usable price
Massachusetts MA6not enough hospitals filed a usable price
Illinois IL5not enough hospitals filed a usable price
Michigan MI4not enough hospitals filed a usable price
Virginia VA4not enough hospitals filed a usable price
Florida FL2not enough hospitals filed a usable price
Iowa IA2not enough hospitals filed a usable price
Louisiana LA2not enough hospitals filed a usable price
Missouri MO2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Washington WA2not enough hospitals filed a usable price
West Virginia WV2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Arizona AZ1not enough hospitals filed a usable price
Colorado CO1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
Nevada NV1not enough hospitals filed a usable price
Tennessee TN1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $288.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care149$262$175 – $403
Children’s4fewer than 20 hospitals
Critical access8fewer than 20 hospitals
Ownership
For-profit8fewer than 20 hospitals
Government15fewer than 20 hospitals
Non-profit138$288$175 – $403
System affiliation
Part of a system145$288$175 – $403
Independent16fewer than 20 hospitals

Cash price vs list price

Median list price (chargemaster)$527
Median cash price$288
Cash as a share of list, median hospital56%

At the typical hospital, asking for the cash price cuts the list price by about 44%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

101 hospitals filed a usable inpatient cash price for this code. The median is $329 and the average of the middle 60% is $349; most fall between $210 and $451.

Cash price percentiles, inpatient, across 101 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$105$281$329$403$566

The most expensive tenth of hospitals charges at least 5.4× what the cheapest tenth charges ($105 vs $566).

Of the 103 hospitals that filed this code inpatient, 101 gave a usable cash price; 1 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 1 a list price only.

How complete is this

161 of the 3,956 hospitals with a price file in our corpus (4%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 166 hospitals that filed this code at all gave us
Usable cash price — counted161
Cash price carrying a plausibility flag — shown on the compare tool, excluded here3
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded1
Hospitals that filed this code166

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as EZH2 GENE COMMON VARIANTS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “EZH2 gene test for common variants (CPT 81237) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81237-ezh2-gene-test-for-common-variants