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Procedure price report · Pathology

EGFR gene test for common tumor variants

CPT 81235the billing code this page is about

Targeted sequencing of selected regions of the EGFR gene to find common variants, often done on lung tumor tissue. Covers one test on one sample.

Hospitals typically charge $644 cash for this outpatient procedure — the median across 1,923 hospitals that filed a usable cash price; the average of the middle 60% is $691. Most fall between $333 and $1,299 (20th–80th percentile).

Hospitals
1,923
States
50
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,923 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$230$373$644$1,129$1,770

The most expensive tenth of hospitals charges at least 7.7× what the cheapest tenth charges ($230 vs $1,770).

How the prices are spread

$176 – $230: 97 hospitals$176$230 – $301: 98 hospitals$301 – $394: 245 hospitals$301$394 – $516: 236 hospitals$516 – $676: 252 hospitals$516$676 – $885: 215 hospitals$885 – $1,158: 224 hospitals$885$1,158 – $1,517: 175 hospitals$1,517 – $1,986: 126 hospitals$1,517$1,986 – $2,600: 64 hospitals$1,986median $644price bands are equal on a log scale
Hospitals per price band (1,732 of 1,923 — the bands cover the 5th to 95th percentile)
FromToHospitals
$176$23097
$230$30198
$301$394245
$394$516236
$516$676252
$676$885215
$885$1,158224
$1,158$1,517175
$1,517$1,986126
$1,986$2,60064

By state

The median cash price in each state, against the national median of $644.

Alaska: 9 hospitals filed a usable price — fewer than 10, so no figureAKMaine: median $437 across 19 hospitalsME$437Vermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $979 across 11 hospitalsNH$979Washington: median $651 across 45 hospitalsWA$651Idaho: median $893 across 14 hospitalsID$893Montana: 4 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $792 across 47 hospitalsMN$792Illinois: median $812 across 72 hospitalsIL$812Wisconsin: median $974 across 82 hospitalsWI$974Michigan: median $657 across 64 hospitalsMI$657New York: median $812 across 69 hospitalsNY$812Massachusetts: median $958 across 41 hospitalsMA$958Oregon: median $390 across 24 hospitalsOR$390Nevada: median $447 across 10 hospitalsNV$447Wyoming: 6 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $351 across 29 hospitalsIA$351Indiana: median $475 across 58 hospitalsIN$475Ohio: median $875 across 92 hospitalsOH$875Pennsylvania: median $549 across 87 hospitalsPA$549New Jersey: median $373 across 47 hospitalsNJ$373Connecticut: median $701 across 15 hospitalsCT$701Rhode Island: 7 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $363 across 75 hospitalsCA$363Utah: median $1,637 across 28 hospitalsUT$1,637Colorado: median $520 across 33 hospitalsCO$520Nebraska: median $716 across 19 hospitalsNE$716Missouri: median $653 across 46 hospitalsMO$653Kentucky: median $647 across 37 hospitalsKY$647West Virginia: median $809 across 23 hospitalsWV$809Virginia: median $758 across 62 hospitalsVA$758Maryland: median $538 across 31 hospitalsMD$538Delaware: 5 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $1,420 across 27 hospitalsAZ$1,420New Mexico: 9 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $666 across 31 hospitalsKS$666Arkansas: median $396 across 22 hospitalsAR$396Tennessee: median $437 across 58 hospitalsTN$437North Carolina: median $487 across 59 hospitalsNC$487South Carolina: median $865 across 39 hospitalsSC$865Oklahoma: median $500 across 37 hospitalsOK$500Louisiana: median $455 across 31 hospitalsLA$455Mississippi: median $288 across 28 hospitalsMS$288Alabama: median $559 across 24 hospitalsAL$559Georgia: median $1,232 across 67 hospitalsGA$1,232Hawaii: 8 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $513 across 160 hospitalsTX$513Florida: median $446 across 100 hospitalsFL$446
Cash price by state, most expensive first. National median $644. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT28$1,637+154%$1,543 – $1,926
Arizona AZ27$1,420+120%$588 – $2,031
Georgia GA67$1,232+91%$538 – $1,684
New Hampshire NH11$979+52%$455 – $1,195
Wisconsin WI82$974+51%$428 – $1,359
Massachusetts MA41$958+49%$533 – $1,241
Idaho ID14$893+39%$388 – $1,819
Ohio OH92$875+36%$536 – $1,456
South Carolina SC39$865+34%$476 – $1,536
New York NY69$812+26%$325 – $1,414
Illinois IL72$812+26%$512 – $1,363
West Virginia WV23$809+26%$260 – $1,964
Minnesota MN47$792+23%$553 – $1,142
Virginia VA62$758+18%$338 – $937
Nebraska NE19$716+11%$498 – $865
Connecticut CT15$701+9%$383 – $1,249
Kansas KS31$666+3%$357 – $1,293
Michigan MI64$657+2%$196 – $1,184
Missouri MO46$653+1%$492 – $1,261
Washington WA45$651+1%$334 – $1,036
Kentucky KY37$6470%$364 – $1,422
Alabama AL24$559−13%$358 – $1,524
Pennsylvania PA87$549−15%$142 – $1,650
Maryland MD31$538−17%$388 – $722
Colorado CO33$520−19%$423 – $1,697
Texas TX160$513−20%$345 – $1,543
Oklahoma OK37$500−22%$175 – $974
North Carolina NC59$487−24%$250 – $685
Indiana IN58$475−26%$373 – $787
Louisiana LA31$455−29%$259 – $752
Nevada NV10$447−31%$54 – $909
Florida FL100$446−31%$240 – $1,058
Tennessee TN58$437−32%$205 – $1,092
Maine ME19$437−32%$256 – $680
Arkansas AR22$396−39%$190 – $722
Oregon OR24$390−40%$312 – $1,509
New Jersey NJ47$373−42%$325 – $1,170
California CA75$363−44%$187 – $834
Iowa IA29$351−45%$351 – $709
Mississippi MS28$288−55%$68 – $584
Alaska AK9not enough hospitals filed a usable price
New Mexico NM9not enough hospitals filed a usable price
Hawaii HI8not enough hospitals filed a usable price
Rhode Island RI7not enough hospitals filed a usable price
Wyoming WY6not enough hospitals filed a usable price
Delaware DE5not enough hospitals filed a usable price
North Dakota ND5not enough hospitals filed a usable price
South Dakota SD5not enough hospitals filed a usable price
Montana MT4not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $644.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,604$617$325 – $1,334
Children’s18fewer than 20 hospitals
Critical access294$723$429 – $1,227
Ownership
For-profit296$950$432 – $1,716
Government247$584$324 – $1,090
Non-profit1,373$616$328 – $1,184
System affiliation
Part of a system1,679$657$334 – $1,351
Independent244$572$325 – $1,164

Cash price vs list price

Median list price (chargemaster)$1,131
Median cash price$644
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,398 hospitals filed a usable inpatient cash price for this code. The median is $639 and the average of the middle 60% is $690; most fall between $338 and $1,303.

Cash price percentiles, inpatient, across 1,398 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$229$377$639$1,132$1,684

The most expensive tenth of hospitals charges at least 7.4× what the cheapest tenth charges ($229 vs $1,684).

Of the 1,550 hospitals that filed this code inpatient, 1,398 gave a usable cash price; 99 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 53 a list price only.

How complete is this

1,923 of the 3,956 hospitals with a price file in our corpus (49%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 2,115 hospitals that filed this code at all gave us
Usable cash price — counted1,923
Cash price carrying a plausibility flag — shown on the compare tool, excluded here133
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded59
Hospitals that filed this code2,115

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Egfr Exons 18-21 by Pcr.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “EGFR gene test for common tumor variants (CPT 81235) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81235-egfr-gene-test-for-common-tumor-variants