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Procedure price report · Pathology

Chromosomal microarray for missing or extra DNA

CPT 81228the billing code this page is about

A whole-genome test that scans a blood or tissue sample for extra or missing chromosome segments, often used to evaluate developmental delay or birth differences.

Hospitals typically charge $1,350 cash for this outpatient procedure — the median across 623 hospitals that filed a usable cash price; the average of the middle 60% is $1,498. Most fall between $758 and $2,700 (20th–80th percentile).

Hospitals
623
States
46
Filings dated
Jul 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 623 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$472$874$1,350$2,550$4,037

The most expensive tenth of hospitals charges at least 8.6× what the cheapest tenth charges ($472 vs $4,037).

How the prices are spread

$251 – $344: 10 hospitals$251$344 – $472: 22 hospitals$472 – $648: 35 hospitals$472$648 – $888: 61 hospitals$888 – $1,218: 106 hospitals$888$1,218 – $1,671: 105 hospitals$1,671 – $2,292: 78 hospitals$1,671$2,292 – $3,143: 76 hospitals$3,143 – $4,311: 50 hospitals$3,143$4,311 – $5,912: 18 hospitals$4,311median $1,350price bands are equal on a log scale
Hospitals per price band (561 of 623 — the bands cover the 5th to 95th percentile)
FromToHospitals
$251$34410
$344$47222
$472$64835
$648$88861
$888$1,218106
$1,218$1,671105
$1,671$2,29278
$2,292$3,14376
$3,143$4,31150
$4,311$5,91218

By state

The median cash price in each state, against the national median of $1,350.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 2 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 1 hospital filed a usable price — fewer than 10, so no figureVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $988 across 13 hospitalsWA$988Idaho: 1 hospital filed a usable price — fewer than 10, so no figureIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $1,363 across 17 hospitalsMN$1,363Illinois: median $2,335 across 26 hospitalsIL$2,335Wisconsin: median $2,616 across 41 hospitalsWI$2,616Michigan: median $1,303 across 16 hospitalsMI$1,303New York: median $1,080 across 33 hospitalsNY$1,080Massachusetts: 2 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 9 hospitals filed a usable price — fewer than 10, so no figureORNevada: 1 hospital filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $864 across 17 hospitalsIA$864Indiana: median $1,296 across 31 hospitalsIN$1,296Ohio: median $3,236 across 30 hospitalsOH$3,236Pennsylvania: median $1,022 across 25 hospitalsPA$1,022New Jersey: median $990 across 26 hospitalsNJ$990Connecticut: 8 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $2,055 across 21 hospitalsCA$2,055Utah: 2 hospitals filed a usable price — fewer than 10, so no figureUTColorado: median $1,080 across 16 hospitalsCO$1,080Nebraska: 7 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $1,078 across 24 hospitalsMO$1,078Kentucky: 8 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: 5 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $1,264 across 11 hospitalsVA$1,264Maryland: median $2,608 across 13 hospitalsMD$2,608Delaware: 1 hospital filed a usable price — fewer than 10, so no figureDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 3 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 5 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 5 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $532 across 14 hospitalsTN$532North Carolina: 7 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: no hospital in the corpus filed a usable priceSCOklahoma: median $1,149 across 23 hospitalsOK$1,149Louisiana: median $1,240 across 13 hospitalsLA$1,240Mississippi: 9 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 3 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $2,971 across 39 hospitalsGA$2,971Hawaii: no hospital in the corpus filed a usable priceHITexas: median $1,434 across 61 hospitalsTX$1,434Florida: median $347 across 17 hospitalsFL$347
Cash price by state, most expensive first. National median $1,350. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Ohio OH30$3,236+140%$1,135 – $3,791
Georgia GA39$2,971+120%$705 – $3,128
Wisconsin WI41$2,616+94%$2,541 – $7,231
Maryland MD13$2,608+93%$1,436 – $3,556
Illinois IL26$2,335+73%$1,391 – $4,186
California CA21$2,055+52%$2,055 – $2,055
Texas TX61$1,434+6%$305 – $1,854
Minnesota MN17$1,363+1%$1,363 – $1,385
Michigan MI16$1,303−3%$1,242 – $2,616
Indiana IN31$1,296−4%$859 – $1,843
Virginia VA11$1,264−6%$1,264 – $1,683
Louisiana LA13$1,240−8%$688 – $1,898
Oklahoma OK23$1,149−15%$365 – $2,470
Colorado CO16$1,080−20%$874 – $7,405
New York NY33$1,080−20%$900 – $2,638
Missouri MO24$1,078−20%$624 – $1,481
Pennsylvania PA25$1,022−24%$123 – $1,035
New Jersey NJ26$990−27%$900 – $990
Washington WA13$988−27%$520 – $2,533
Iowa IA17$864−36%$864 – $1,362
Tennessee TN14$532−61%$299 – $1,140
Florida FL17$347−74%$80 – $1,308
Mississippi MS9not enough hospitals filed a usable price
Oregon OR9not enough hospitals filed a usable price
Connecticut CT8not enough hospitals filed a usable price
Kentucky KY8not enough hospitals filed a usable price
North Carolina NC7not enough hospitals filed a usable price
Nebraska NE7not enough hospitals filed a usable price
Arkansas AR5not enough hospitals filed a usable price
Kansas KS5not enough hospitals filed a usable price
North Dakota ND5not enough hospitals filed a usable price
West Virginia WV5not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Alabama AL3not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
New Mexico NM3not enough hospitals filed a usable price
Massachusetts MA2not enough hospitals filed a usable price
Maine ME2not enough hospitals filed a usable price
Utah UT2not enough hospitals filed a usable price
Delaware DE1not enough hospitals filed a usable price
Idaho ID1not enough hospitals filed a usable price
Nevada NV1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Vermont VT1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $1,350.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care497$1,302$814 – $2,971
Children’s21$1,592$694 – $2,421
Critical access101$1,385$705 – $2,616
Ownership
For-profit46$1,829$855 – $4,327
Government74$900$574 – $2,533
Non-profit499$1,350$859 – $2,616
System affiliation
Part of a system567$1,363$828 – $2,744
Independent56$1,090$694 – $2,470

Cash price vs list price

Median list price (chargemaster)$2,700
Median cash price$1,350
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

437 hospitals filed a usable inpatient cash price for this code. The median is $1,369 and the average of the middle 60% is $1,492; most fall between $701 and $2,638.

Cash price percentiles, inpatient, across 437 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$389$828$1,369$2,550$3,700

The most expensive tenth of hospitals charges at least 9.5× what the cheapest tenth charges ($389 vs $3,700).

Of the 491 hospitals that filed this code inpatient, 437 gave a usable cash price; 24 carried a plausibility flag, 1 filed a number their own filing marks as not a price, 0 gave an estimate, and 29 a list price only.

How complete is this

623 of the 3,956 hospitals with a price file in our corpus (16%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 679 hospitals that filed this code at all gave us
Usable cash price — counted623
Cash price carrying a plausibility flag — shown on the compare tool, excluded here29
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded3
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded24
Hospitals that filed this code679

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as CYTOG ALYS CHRML ABNR CGH.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Chromosomal microarray for missing or extra DNA (CPT 81228) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81228-chromosomal-microarray-for-missing-or-extra-dna