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Procedure price report · Pathology

Cystic fibrosis gene test, full sequence

CPT 81223the billing code this page is about

A genetic test that reads the entire coding sequence of the CFTR gene to look for any change, including rare ones not on standard panels.

Hospitals typically charge $1,012 cash for this outpatient procedure — the median across 1,222 hospitals that filed a usable cash price; the average of the middle 60% is $1,050. Most fall between $537 and $1,915 (20th–80th percentile).

Hospitals
1,222
States
49
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,222 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$409$599$1,012$1,627$3,002

The most expensive tenth of hospitals charges at least 7.3× what the cheapest tenth charges ($409 vs $3,002).

How the prices are spread

$241 – $321: 24 hospitals$241$321 – $429: 45 hospitals$429 – $573: 155 hospitals$429$573 – $764: 149 hospitals$764 – $1,020: 179 hospitals$764$1,020 – $1,362: 207 hospitals$1,362 – $1,818: 128 hospitals$1,362$1,818 – $2,426: 117 hospitals$2,426 – $3,239: 47 hospitals$2,426$3,239 – $4,323: 49 hospitals$3,239median $1,012price bands are equal on a log scale
Hospitals per price band (1,100 of 1,222 — the bands cover the 5th to 95th percentile)
FromToHospitals
$241$32124
$321$42945
$429$573155
$573$764149
$764$1,020179
$1,020$1,362207
$1,362$1,818128
$1,818$2,426117
$2,426$3,23947
$3,239$4,32349

By state

The median cash price in each state, against the national median of $1,012.

Alaska: 3 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 3 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 1 hospital filed a usable price — fewer than 10, so no figureVTNew Hampshire: 2 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $774 across 29 hospitalsWA$774Idaho: median $970 across 11 hospitalsID$970Montana: 2 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: 4 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $507 across 26 hospitalsMN$507Illinois: median $1,541 across 73 hospitalsIL$1,541Wisconsin: median $1,100 across 59 hospitalsWI$1,100Michigan: median $716 across 29 hospitalsMI$716New York: median $838 across 47 hospitalsNY$838Massachusetts: median $1,060 across 18 hospitalsMA$1,060Oregon: median $758 across 20 hospitalsOR$758Nevada: 9 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $479 across 18 hospitalsIA$479Indiana: median $757 across 43 hospitalsIN$757Ohio: median $1,141 across 78 hospitalsOH$1,141Pennsylvania: median $2,108 across 51 hospitalsPA$2,108New Jersey: median $549 across 40 hospitalsNJ$549Connecticut: 6 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $940 across 42 hospitalsCA$940Utah: median $1,280 across 33 hospitalsUT$1,280Colorado: median $946 across 31 hospitalsCO$946Nebraska: 9 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $1,200 across 37 hospitalsMO$1,200Kentucky: median $1,307 across 19 hospitalsKY$1,307West Virginia: median $1,132 across 13 hospitalsWV$1,132Virginia: median $3,352 across 27 hospitalsVA$3,352Maryland: median $1,128 across 25 hospitalsMD$1,128Delaware: 5 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $636 across 11 hospitalsAZ$636New Mexico: 4 hospitals filed a usable price — fewer than 10, so no figureNMKansas: 8 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: median $1,042 across 10 hospitalsAR$1,042Tennessee: median $861 across 24 hospitalsTN$861North Carolina: median $953 across 44 hospitalsNC$953South Carolina: median $1,435 across 28 hospitalsSC$1,435Oklahoma: median $785 across 35 hospitalsOK$785Louisiana: median $639 across 25 hospitalsLA$639Mississippi: median $503 across 19 hospitalsMS$503Alabama: median $599 across 11 hospitalsAL$599Georgia: median $1,627 across 42 hospitalsGA$1,627Hawaii: 2 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $950 across 110 hospitalsTX$950Florida: median $349 across 31 hospitalsFL$349
Cash price by state, most expensive first. National median $1,012. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Virginia VA27$3,352+231%$1,040 – $9,771
Pennsylvania PA51$2,108+108%$346 – $4,107
Georgia GA42$1,627+61%$1,059 – $2,025
Illinois IL73$1,541+52%$953 – $2,716
South Carolina SC28$1,435+42%$1,138 – $1,896
Kentucky KY19$1,307+29%$463 – $1,865
Utah UT33$1,280+27%$960 – $1,506
Missouri MO37$1,200+19%$986 – $2,780
Ohio OH78$1,141+13%$714 – $2,073
West Virginia WV13$1,132+12%$853 – $2,400
Maryland MD25$1,128+12%$717 – $2,617
Wisconsin WI59$1,100+9%$772 – $1,409
Massachusetts MA18$1,060+5%$693 – $1,720
Arkansas AR10$1,042+3%$299 – $1,042
Idaho ID11$970−4%$833 – $1,740
North Carolina NC44$953−6%$667 – $2,000
Texas TX110$950−6%$563 – $1,320
Colorado CO31$946−6%$570 – $2,144
California CA42$940−7%$499 – $3,326
Tennessee TN24$861−15%$649 – $1,040
New York NY47$838−17%$499 – $2,174
Oklahoma OK35$785−22%$396 – $1,191
Washington WA29$774−23%$732 – $1,399
Oregon OR20$758−25%$659 – $1,512
Indiana IN43$757−25%$153 – $1,521
Michigan MI29$716−29%$578 – $772
Louisiana LA25$639−37%$346 – $1,116
Arizona AZ11$636−37%$444 – $734
Alabama AL11$599−41%$499 – $1,825
New Jersey NJ40$549−46%$499 – $584
Minnesota MN26$507−50%$502 – $646
Mississippi MS19$503−50%$337 – $758
Iowa IA18$479−53%$479 – $1,091
Florida FL31$349−65%$124 – $807
Nebraska NE9not enough hospitals filed a usable price
Nevada NV9not enough hospitals filed a usable price
Kansas KS8not enough hospitals filed a usable price
Connecticut CT6not enough hospitals filed a usable price
Delaware DE5not enough hospitals filed a usable price
North Dakota ND4not enough hospitals filed a usable price
New Mexico NM4not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price
Alaska AK3not enough hospitals filed a usable price
Maine ME3not enough hospitals filed a usable price
Hawaii HI2not enough hospitals filed a usable price
Montana MT2not enough hospitals filed a usable price
New Hampshire NH2not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Vermont VT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $1,012.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care982$971$513 – $1,945
Children’s37$926$499 – $1,820
Critical access197$1,026$649 – $1,785
Ownership
For-profit132$950$503 – $1,822
Government140$749$489 – $1,483
Non-profit944$1,040$549 – $2,000
System affiliation
Part of a system1,087$1,022$537 – $1,945
Independent135$940$551 – $1,740

Cash price vs list price

Median list price (chargemaster)$1,859
Median cash price$1,012
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

887 hospitals filed a usable inpatient cash price for this code. The median is $1,050 and the average of the middle 60% is $1,096; most fall between $559 and $1,996.

Cash price percentiles, inpatient, across 887 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$428$643$1,050$1,627$3,002

The most expensive tenth of hospitals charges at least 7.0× what the cheapest tenth charges ($428 vs $3,002).

Of the 1,009 hospitals that filed this code inpatient, 887 gave a usable cash price; 70 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 52 a list price only.

How complete is this

1,222 of the 3,956 hospitals with a price file in our corpus (31%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,365 hospitals that filed this code at all gave us
Usable cash price — counted1,222
Cash price carrying a plausibility flag — shown on the compare tool, excluded here92
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded50
Hospitals that filed this code1,365

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as CFTR GENE FULL SEQUENCE.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Cystic fibrosis gene test, full sequence (CPT 81223) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81223-cystic-fibrosis-gene-test-full-sequence