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Procedure price report · Pathology

Cystic fibrosis gene test, common variants panel

CPT 81220the billing code this page is about

A genetic test of the CFTR gene that screens for a standard panel of the more frequently seen cystic fibrosis variants rather than reading the entire gene.

Hospitals typically charge $500 cash for this outpatient procedure — the median across 2,508 hospitals that filed a usable cash price; the average of the middle 60% is $542. Most fall between $206 and $1,129 (20th–80th percentile).

Hospitals
2,508
States
50
Filings dated
Dec 2022 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 2,508 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$119$247$500$961$1,670

The most expensive tenth of hospitals charges at least 14× what the cheapest tenth charges ($119 vs $1,670).

How the prices are spread

$74 – $106: 89 hospitals$74$106 – $150: 140 hospitals$150 – $213: 182 hospitals$150$213 – $303: 253 hospitals$303 – $431: 324 hospitals$303$431 – $612: 367 hospitals$612 – $870: 340 hospitals$612$870 – $1,236: 252 hospitals$1,236 – $1,757: 213 hospitals$1,236$1,757 – $2,497: 109 hospitals$1,757median $500price bands are equal on a log scale
Hospitals per price band (2,269 of 2,508 — the bands cover the 5th to 95th percentile)
FromToHospitals
$74$10689
$106$150140
$150$213182
$213$303253
$303$431324
$431$612367
$612$870340
$870$1,236252
$1,236$1,757213
$1,757$2,497109

By state

The median cash price in each state, against the national median of $500.

Alaska: median $731 across 13 hospitalsAK$731Maine: median $308 across 25 hospitalsME$308Vermont: median $530 across 13 hospitalsVT$530New Hampshire: median $1,178 across 22 hospitalsNH$1,178Washington: median $629 across 52 hospitalsWA$629Idaho: median $238 across 17 hospitalsID$238Montana: median $557 across 16 hospitalsMT$557North Dakota: median $1,002 across 15 hospitalsND$1,002Minnesota: median $279 across 64 hospitalsMN$279Illinois: median $559 across 124 hospitalsIL$559Wisconsin: median $419 across 92 hospitalsWI$419Michigan: median $521 across 57 hospitalsMI$521New York: median $668 across 113 hospitalsNY$668Massachusetts: median $1,066 across 44 hospitalsMA$1,066Oregon: median $327 across 40 hospitalsOR$327Nevada: median $404 across 16 hospitalsNV$404Wyoming: median $904 across 15 hospitalsWY$904South Dakota: 9 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $503 across 46 hospitalsIA$503Indiana: median $695 across 82 hospitalsIN$695Ohio: median $514 across 129 hospitalsOH$514Pennsylvania: median $730 across 114 hospitalsPA$730New Jersey: median $612 across 55 hospitalsNJ$612Connecticut: median $1,029 across 15 hospitalsCT$1,029Rhode Island: median $956 across 10 hospitalsRI$956California: median $242 across 118 hospitalsCA$242Utah: median $460 across 33 hospitalsUT$460Colorado: median $527 across 61 hospitalsCO$527Nebraska: median $464 across 30 hospitalsNE$464Missouri: median $490 across 66 hospitalsMO$490Kentucky: median $427 across 49 hospitalsKY$427West Virginia: median $178 across 36 hospitalsWV$178Virginia: median $843 across 63 hospitalsVA$843Maryland: median $197 across 34 hospitalsMD$197Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $748 across 26 hospitalsAZ$748New Mexico: median $717 across 10 hospitalsNM$717Kansas: median $686 across 37 hospitalsKS$686Arkansas: median $488 across 20 hospitalsAR$488Tennessee: median $401 across 53 hospitalsTN$401North Carolina: median $360 across 74 hospitalsNC$360South Carolina: median $896 across 45 hospitalsSC$896Oklahoma: median $416 across 51 hospitalsOK$416Louisiana: median $460 across 38 hospitalsLA$460Mississippi: median $284 across 39 hospitalsMS$284Alabama: median $626 across 28 hospitalsAL$626Georgia: median $300 across 87 hospitalsGA$300Hawaii: 8 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $338 across 179 hospitalsTX$338Florida: median $175 across 118 hospitalsFL$175
Cash price by state, most expensive first. National median $500. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
New Hampshire NH22$1,178+136%$684 – $1,525
Massachusetts MA44$1,066+113%$662 – $1,920
Connecticut CT15$1,029+106%$455 – $1,742
North Dakota ND15$1,002+100%$207 – $1,336
Rhode Island RI10$956+91%$712 – $1,790
Wyoming WY15$904+81%$352 – $1,480
South Carolina SC45$896+79%$389 – $965
Virginia VA63$843+69%$166 – $1,500
Arizona AZ26$748+50%$202 – $5,724
Alaska AK13$731+46%$501 – $1,737
Pennsylvania PA114$730+46%$243 – $3,094
New Mexico NM10$717+43%$273 – $1,192
Indiana IN82$695+39%$344 – $1,026
Kansas KS37$686+37%$284 – $2,324
New York NY113$668+34%$282 – $1,632
Washington WA52$629+26%$421 – $844
Alabama AL28$626+25%$254 – $836
New Jersey NJ55$612+22%$557 – $645
Illinois IL124$559+12%$286 – $836
Montana MT16$557+11%$189 – $970
Vermont VT13$530+6%$323 – $1,473
Colorado CO61$527+5%$332 – $921
Michigan MI57$521+4%$145 – $1,174
Ohio OH129$514+3%$339 – $1,192
Iowa IA46$503+1%$216 – $792
Missouri MO66$490−2%$328 – $836
Arkansas AR20$488−2%$180 – $565
Nebraska NE30$464−7%$210 – $1,064
Utah UT33$460−8%$328 – $541
Louisiana LA38$460−8%$232 – $1,062
Kentucky KY49$427−15%$199 – $964
Wisconsin WI92$419−16%$253 – $2,011
Oklahoma OK51$416−17%$300 – $704
Nevada NV16$404−19%$98 – $1,059
Tennessee TN53$401−20%$182 – $1,511
North Carolina NC74$360−28%$114 – $970
Texas TX179$338−32%$168 – $806
Oregon OR40$327−35%$197 – $551
Maine ME25$308−38%$206 – $1,274
Georgia GA87$300−40%$187 – $786
Mississippi MS39$284−43%$147 – $516
Minnesota MN64$279−44%$188 – $558
California CA118$242−52%$70 – $868
Idaho ID17$238−52%$229 – $1,007
Maryland MD34$197−61%$114 – $463
West Virginia WV36$178−64%$125 – $1,159
Florida FL118$175−65%$63 – $455
South Dakota SD9not enough hospitals filed a usable price
Hawaii HI8not enough hospitals filed a usable price
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $500.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,910$524$197 – $1,145
Children’s40$565$254 – $846
Critical access549$469$222 – $1,063
Ownership
For-profit319$459$167 – $1,192
Government406$431$165 – $904
Non-profit1,774$533$220 – $1,172
System affiliation
Part of a system2,088$490$207 – $1,130
Independent420$522$192 – $1,113

Cash price vs list price

Median list price (chargemaster)$840
Median cash price$500
Cash as a share of list, median hospital62%

At the typical hospital, asking for the cash price cuts the list price by about 38%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,769 hospitals filed a usable inpatient cash price for this code. The median is $526 and the average of the middle 60% is $567; most fall between $218 and $1,185.

Cash price percentiles, inpatient, across 1,769 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$135$256$526$996$1,749

The most expensive tenth of hospitals charges at least 13× what the cheapest tenth charges ($135 vs $1,749).

Of the 1,959 hospitals that filed this code inpatient, 1,769 gave a usable cash price; 109 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 81 a list price only.

How complete is this

2,508 of the 3,956 hospitals with a price file in our corpus (63%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 2,757 hospitals that filed this code at all gave us
Usable cash price — counted2,508
Cash price carrying a plausibility flag — shown on the compare tool, excluded here150
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded97
Hospitals that filed this code2,757

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between July 20, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Cystic Fibrosis Scn.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Cystic fibrosis gene test, common variants panel (CPT 81220) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81220-cystic-fibrosis-gene-test-common-variants-panel