Procedure price report · Pathology

BRCA2 gene test, full sequence

CPT code CPT 81216the billing code this page is about

A genetic test that reads the entire coding sequence of the BRCA2 gene to look for changes linked to hereditary breast and ovarian cancer risk.

Hospitals typically charge $254 cash for this outpatient procedure — the median across 250 hospitals that filed a usable cash price; the average of the middle 60% is $305. Most fall between $178 and $660 (20th–80th percentile).

Hospitals
250
States
35
Filings dated
Aug 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 250 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$90$185$254$578$2,449

The most expensive tenth of hospitals charges at least 27× what the cheapest tenth charges ($90 vs $2,449).

How the prices are spread

$76 – $108: 22 hospitals$76$108 – $153: 2 hospitals$153 – $216: 64 hospitals$153$216 – $306: 56 hospitals$306 – $434: 14 hospitals$306$434 – $614: 19 hospitals$614 – $870: 20 hospitals$614$870 – $1,231: 4 hospitals$1,231 – $1,744: 6 hospitals$1,231$1,744 – $2,470: 25 hospitals$1,744median $254price bands are equal on a log scale
Hospitals per price band (232 of 250 — the bands cover the 5th to 95th percentile)
FromToHospitals
$76$10822
$108$1532
$153$21664
$216$30656
$306$43414
$434$61419
$614$87020
$870$1,2314
$1,231$1,7446
$1,744$2,47025

By state

The median cash price in each state, against the national median of $254.

Alaska: 2 hospitals filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: median $547 across 10 hospitalsWA$547Idaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: 9 hospitals filed a usable price — fewer than 10, so no figureMNIllinois: 6 hospitals filed a usable price — fewer than 10, so no figureILWisconsin: 2 hospitals filed a usable price — fewer than 10, so no figureWIMichigan: median $255 across 10 hospitalsMI$255New York: median $185 across 16 hospitalsNY$185Massachusetts: 3 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 4 hospitals filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $178 across 11 hospitalsIA$178Indiana: median $272 across 12 hospitalsIN$272Ohio: median $658 across 13 hospitalsOH$658Pennsylvania: median $278 across 18 hospitalsPA$278New Jersey: median $204 across 22 hospitalsNJ$204Connecticut: 5 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $2,470 across 22 hospitalsCA$2,470Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: 2 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 2 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 2 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 4 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: no hospital in the corpus filed a usable priceWVVirginia: median $195 across 11 hospitalsVA$195Maryland: no hospital in the corpus filed a usable priceMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 1 hospital filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 5 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: no hospital in the corpus filed a usable priceNCSouth Carolina: 1 hospital filed a usable price — fewer than 10, so no figureSCOklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 2 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: no hospital in the corpus filed a usable priceMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: median $305 across 13 hospitalsGA$305Hawaii: no hospital in the corpus filed a usable priceHITexas: median $222 across 23 hospitalsTX$222Florida: 9 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $254. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
California CA22$2,470+873%$2,470 – $2,470
Ohio OH13$658+159%$466 – $1,875
Washington WA10$547+116%$281 – $893
Georgia GA13$305+20%$305 – $305
Pennsylvania PA18$278+9%$224 – $650
Indiana IN12$272+7%$239 – $367
Michigan MI10$255+1%$255 – $645
Texas TX23$222−12%$58 – $222
New Jersey NJ22$204−20%$185 – $204
Virginia VA11$195−23%$195 – $5,756
New York NY16$185−27%$185 – $244
Iowa IA11$178−30%$178 – $178
Florida FL9not enough hospitals filed a usable price
Minnesota MN9not enough hospitals filed a usable price
Illinois IL6not enough hospitals filed a usable price
Connecticut CT5not enough hospitals filed a usable price
Tennessee TN5not enough hospitals filed a usable price
Kentucky KY4not enough hospitals filed a usable price
Oregon OR4not enough hospitals filed a usable price
Massachusetts MA3not enough hospitals filed a usable price
Alaska AK2not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Colorado CO2not enough hospitals filed a usable price
Louisiana LA2not enough hospitals filed a usable price
Missouri MO2not enough hospitals filed a usable price
Nebraska NE2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Wisconsin WI2not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
Arizona AZ1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
South Carolina SC1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $254.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care214$234$178 – $771
Children’s15fewer than 20 hospitals
Critical access21$386$222 – $428
Ownership
For-profit16fewer than 20 hospitals
Government25$185$173 – $428
Non-profit209$255$178 – $773
System affiliation
Part of a system230$254$178 – $771
Independent20$227$185 – $555

Cash price vs list price

Median list price (chargemaster)$648
Median cash price$254
Cash as a share of list, median hospital56%

At the typical hospital, asking for the cash price cuts the list price by about 44%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

146 hospitals filed a usable inpatient cash price for this code. The median is $305 and the average of the middle 60% is $466; most fall between $178 and $1,875.

Cash price percentiles, inpatient, across 146 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$90$194$305$939$2,470

The most expensive tenth of hospitals charges at least 27× what the cheapest tenth charges ($90 vs $2,470).

Of the 163 hospitals that filed this code inpatient, 146 gave a usable cash price; 10 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 7 a list price only.

How complete is this

250 of the 3,956 hospitals with a price file in our corpus (6%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 268 hospitals that filed this code at all gave us
Usable cash price — counted250
Cash price carrying a plausibility flag — shown on the compare tool, excluded here9
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded8
Hospitals that filed this code268

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Hospitals file this code under descriptions such as BRCA2 GENE FULL SEQ ALYS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “BRCA2 gene test, full sequence (CPT 81216) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81216-brca2-gene-test-full-sequence