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Procedure price report · Pathology

IDH2 gene test for common changes

CPT 81121the billing code this page is about

A laboratory test that looks for the most frequent mutations in the IDH2 gene, usually run on tumor tissue such as brain tumor or leukemia samples.

Hospitals typically charge $426 cash for this outpatient procedure — the median across 1,109 hospitals that filed a usable cash price; the average of the middle 60% is $450. Most fall between $244 and $778 (20th–80th percentile).

Hospitals
1,109
States
49
Filings dated
Aug 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,109 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$173$267$426$699$987

The most expensive tenth of hospitals charges at least 5.7× what the cheapest tenth charges ($173 vs $987).

How the prices are spread

$135 – $169: 33 hospitals$135$169 – $211: 79 hospitals$211 – $263: 104 hospitals$211$263 – $328: 142 hospitals$328 – $409: 113 hospitals$328$409 – $510: 149 hospitals$510 – $636: 101 hospitals$510$636 – $793: 116 hospitals$793 – $989: 110 hospitals$793$989 – $1,234: 52 hospitals$989median $426price bands are equal on a log scale
Hospitals per price band (999 of 1,109 — the bands cover the 5th to 95th percentile)
FromToHospitals
$135$16933
$169$21179
$211$263104
$263$328142
$328$409113
$409$510149
$510$636101
$636$793116
$793$989110
$989$1,23452

By state

The median cash price in each state, against the national median of $426.

Alaska: 2 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 6 hospitals filed a usable price — fewer than 10, so no figureMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $266 across 29 hospitalsWA$266Idaho: median $600 across 13 hospitalsID$600Montana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: 4 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $505 across 40 hospitalsMN$505Illinois: median $418 across 49 hospitalsIL$418Wisconsin: median $560 across 72 hospitalsWI$560Michigan: median $356 across 45 hospitalsMI$356New York: median $431 across 33 hospitalsNY$431Massachusetts: median $918 across 21 hospitalsMA$918Oregon: median $255 across 20 hospitalsOR$255Nevada: 4 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: 1 hospital filed a usable price — fewer than 10, so no figureSDIowa: median $284 across 14 hospitalsIA$284Indiana: median $426 across 28 hospitalsIN$426Ohio: median $669 across 69 hospitalsOH$669Pennsylvania: median $340 across 29 hospitalsPA$340New Jersey: median $325 across 35 hospitalsNJ$325Connecticut: 7 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $425 across 42 hospitalsCA$425Utah: median $624 across 23 hospitalsUT$624Colorado: median $384 across 25 hospitalsCO$384Nebraska: 3 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $446 across 33 hospitalsMO$446Kentucky: median $489 across 23 hospitalsKY$489West Virginia: 6 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: median $380 across 30 hospitalsVA$380Maryland: median $458 across 17 hospitalsMD$458Delaware: 2 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $992 across 16 hospitalsAZ$992New Mexico: 3 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $307 across 13 hospitalsKS$307Arkansas: median $458 across 15 hospitalsAR$458Tennessee: median $316 across 39 hospitalsTN$316North Carolina: median $470 across 37 hospitalsNC$470South Carolina: median $662 across 21 hospitalsSC$662Oklahoma: median $430 across 31 hospitalsOK$430Louisiana: median $395 across 12 hospitalsLA$395Mississippi: median $188 across 12 hospitalsMS$188Alabama: 5 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $267 across 56 hospitalsGA$267Hawaii: 4 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $371 across 76 hospitalsTX$371Florida: median $226 across 37 hospitalsFL$226
Cash price by state, most expensive first. National median $426. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Arizona AZ16$992+133%$452 – $1,163
Massachusetts MA21$918+115%$503 – $1,243
Ohio OH69$669+57%$233 – $1,327
South Carolina SC21$662+55%$662 – $1,642
Utah UT23$624+46%$624 – $735
Idaho ID13$600+41%$350 – $624
Wisconsin WI72$560+31%$305 – $835
Minnesota MN40$505+18%$105 – $553
Kentucky KY23$489+15%$251 – $702
North Carolina NC37$470+10%$289 – $644
Arkansas AR15$458+7%$144 – $519
Maryland MD17$458+7%$363 – $611
Missouri MO33$446+4%$321 – $559
New York NY33$431+1%$296 – $924
Oklahoma OK31$430+1%$248 – $476
Indiana IN28$4260%$330 – $672
California CA42$4250%$135 – $806
Illinois IL49$418−2%$223 – $917
Louisiana LA12$395−7%$246 – $757
Colorado CO25$384−10%$184 – $813
Virginia VA30$380−11%$252 – $703
Texas TX76$371−13%$207 – $444
Michigan MI45$356−16%$177 – $590
Pennsylvania PA29$340−20%$204 – $807
New Jersey NJ35$325−24%$296 – $476
Tennessee TN39$316−26%$232 – $503
Kansas KS13$307−28%$259 – $1,115
Iowa IA14$284−33%$284 – $284
Georgia GA56$267−37%$173 – $645
Washington WA29$266−38%$170 – $819
Oregon OR20$255−40%$255 – $704
Florida FL37$226−47%$106 – $388
Mississippi MS12$188−56%$164 – $362
Connecticut CT7not enough hospitals filed a usable price
Maine ME6not enough hospitals filed a usable price
West Virginia WV6not enough hospitals filed a usable price
Alabama AL5not enough hospitals filed a usable price
Hawaii HI4not enough hospitals filed a usable price
North Dakota ND4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
Nevada NV4not enough hospitals filed a usable price
Nebraska NE3not enough hospitals filed a usable price
New Mexico NM3not enough hospitals filed a usable price
Alaska AK2not enough hospitals filed a usable price
Delaware DE2not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
South Dakota SD1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $426.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care927$415$234 – $762
Children’s17fewer than 20 hospitals
Critical access159$473$259 – $787
Ownership
For-profit100$426$217 – $978
Government126$316$183 – $644
Non-profit877$444$255 – $794
System affiliation
Part of a system1,018$431$245 – $778
Independent91$362$233 – $800

Cash price vs list price

Median list price (chargemaster)$810
Median cash price$426
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

865 hospitals filed a usable inpatient cash price for this code. The median is $444 and the average of the middle 60% is $465; most fall between $242 and $806.

Cash price percentiles, inpatient, across 865 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$184$259$444$718$1,038

The most expensive tenth of hospitals charges at least 5.6× what the cheapest tenth charges ($184 vs $1,038).

Of the 918 hospitals that filed this code inpatient, 865 gave a usable cash price; 30 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 23 a list price only.

How complete is this

1,109 of the 3,956 hospitals with a price file in our corpus (28%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,169 hospitals that filed this code at all gave us
Usable cash price — counted1,109
Cash price carrying a plausibility flag — shown on the compare tool, excluded here36
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded23
Hospitals that filed this code1,169

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Pathology family.

Hospitals file this code under descriptions such as HC Idh2 Ngs.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “IDH2 gene test for common changes (CPT 81121) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-81121-idh2-gene-test-for-common-changes