Procedure price report · Pathology

Spinal fluid test for infection using DNA sequencing

CPT code CPT 0480Uthe billing code this page is about

Laboratory analysis of cerebrospinal fluid that sequences genetic material from many organisms at once to look for bacteria, viruses, fungi or parasites causing infection.

Hospitals typically charge $3,298 cash for this outpatient procedure — the median across 158 hospitals that filed a usable cash price; the average of the middle 60% is $3,576. Most fall between $2,250 and $4,500 (20th–80th percentile).

Hospitals
158
States
20
Filings dated
Oct 2025 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 23, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 158 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$2,041$2,847$3,298$4,500$5,400

The most expensive tenth of hospitals charges at least 2.6× what the cheapest tenth charges ($2,041 vs $5,400).

How the prices are spread

$1,607 – $1,844: 8 hospitals$1,607$1,844 – $2,117: 13 hospitals$2,117 – $2,430: 8 hospitals$2,117$2,430 – $2,789: 3 hospitals$2,789 – $3,201: 34 hospitals$2,789$3,201 – $3,675: 19 hospitals$3,675 – $4,218: 2 hospitals$3,675$4,218 – $4,841: 39 hospitals$4,841 – $5,557: 12 hospitals$4,841$5,557 – $6,379: 12 hospitals$5,557median $3,298price bands are equal on a log scale
Hospitals per price band (150 of 158 — the bands cover the 5th to 95th percentile)
FromToHospitals
$1,607$1,8448
$1,844$2,11713
$2,117$2,4308
$2,430$2,7893
$2,789$3,20134
$3,201$3,67519
$3,675$4,2182
$4,218$4,84139
$4,841$5,55712
$5,557$6,37912

By state

The median cash price in each state, against the national median of $3,298.

Alaska: no hospital in the corpus filed a usable priceAKMaine: no hospital in the corpus filed a usable priceMEVermont: no hospital in the corpus filed a usable priceVTNew Hampshire: no hospital in the corpus filed a usable priceNHWashington: no hospital in the corpus filed a usable priceWAIdaho: no hospital in the corpus filed a usable priceIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: median $3,007 across 18 hospitalsMN$3,007Illinois: median $4,465 across 11 hospitalsIL$4,465Wisconsin: median $3,298 across 12 hospitalsWI$3,298Michigan: 8 hospitals filed a usable price — fewer than 10, so no figureMINew York: 4 hospitals filed a usable price — fewer than 10, so no figureNYMassachusetts: no hospital in the corpus filed a usable priceMAOregon: no hospital in the corpus filed a usable priceORNevada: no hospital in the corpus filed a usable priceNVWyoming: no hospital in the corpus filed a usable priceWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $2,041 across 11 hospitalsIA$2,041Indiana: no hospital in the corpus filed a usable priceINOhio: 5 hospitals filed a usable price — fewer than 10, so no figureOHPennsylvania: no hospital in the corpus filed a usable pricePANew Jersey: no hospital in the corpus filed a usable priceNJConnecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: no hospital in the corpus filed a usable priceCAUtah: no hospital in the corpus filed a usable priceUTColorado: median $4,050 across 11 hospitalsCO$4,050Nebraska: 1 hospital filed a usable price — fewer than 10, so no figureNEMissouri: no hospital in the corpus filed a usable priceMOKentucky: no hospital in the corpus filed a usable priceKYWest Virginia: no hospital in the corpus filed a usable priceWVVirginia: median $6,379 across 10 hospitalsVA$6,379Maryland: no hospital in the corpus filed a usable priceMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 3 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: no hospital in the corpus filed a usable priceKSArkansas: no hospital in the corpus filed a usable priceARTennessee: 1 hospital filed a usable price — fewer than 10, so no figureTNNorth Carolina: median $5,400 across 12 hospitalsNC$5,400South Carolina: median $3,455 across 12 hospitalsSC$3,455Oklahoma: 2 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: no hospital in the corpus filed a usable priceLAMississippi: no hospital in the corpus filed a usable priceMSAlabama: no hospital in the corpus filed a usable priceALGeorgia: no hospital in the corpus filed a usable priceGAHawaii: no hospital in the corpus filed a usable priceHITexas: median $4,500 across 30 hospitalsTX$4,500Florida: 1 hospital filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $3,298. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Virginia VA10$6,379+93%$3,189 – $6,379
North Carolina NC12$5,400+64%$5,400 – $5,400
Texas TX30$4,500+36%$4,500 – $4,500
Illinois IL11$4,465+35%$4,465 – $4,465
Colorado CO11$4,050+23%$3,150 – $5,250
South Carolina SC12$3,455+5%$3,455 – $3,455
Wisconsin WI12$3,2980%$2,985 – $3,298
Minnesota MN18$3,007−9%$3,007 – $3,008
Iowa IA11$2,041−38%$2,041 – $2,041
Michigan MI8not enough hospitals filed a usable price
Ohio OH5not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
New York NY4not enough hospitals filed a usable price
Arizona AZ3not enough hospitals filed a usable price
Oklahoma OK2not enough hospitals filed a usable price
Florida FL1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
Nebraska NE1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Tennessee TN1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $3,298.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care133$3,455$2,126 – $4,500
Children’s2fewer than 20 hospitals
Critical access22$3,007$2,985 – $4,465
Ownership
For-profit17fewer than 20 hospitals
Government13fewer than 20 hospitals
Non-profit127$3,298$2,126 – $4,500
System affiliation
Part of a system155$3,298$2,250 – $4,500
Independent3fewer than 20 hospitals

Cash price vs list price

Median list price (chargemaster)$6,379
Median cash price$3,298
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

132 hospitals filed a usable inpatient cash price for this code. The median is $3,455 and the average of the middle 60% is $3,610; most fall between $2,363 and $4,500.

Cash price percentiles, inpatient, across 132 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$2,041$2,847$3,455$4,500$5,400

The most expensive tenth of hospitals charges at least 2.6× what the cheapest tenth charges ($2,041 vs $5,400).

Of the 132 hospitals that filed this code inpatient, 132 gave a usable cash price; 0 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 0 a list price only.

How complete is this

158 of the 3,956 hospitals with a price file in our corpus (4%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 160 hospitals that filed this code at all gave us
Usable cash price — counted158
Cash price carrying a plausibility flag — shown on the compare tool, excluded here0
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded2
Hospitals that filed this code160

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 23, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Hospitals file this code under descriptions such as NFCT DS CSF METAG NGS ALYS.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Spinal fluid test for infection using DNA sequencing (CPT 0480U) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-0480u-spinal-fluid-test-for-infection-using-dna-sequencing