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Procedure price report · Prophylactic vaccinations and inoculations

RSV preventive antibody shot for infants, 1 mL dose

CPT 90381the billing code this page is about

Covers the nirsevimab product given as a single muscle injection to help prevent respiratory syncytial virus illness in infants; billed for one 1 mL (100 mg) dose, with the injection charged separately.

Hospitals typically charge $923 cash for this outpatient procedure — the median across 1,114 hospitals that filed a usable cash price; the average of the middle 60% is $924. Most fall between $504 and $1,507 (20th–80th percentile).

Hospitals
1,114
States
48
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,114 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$366$565$923$1,352$2,168

The most expensive tenth of hospitals charges at least 5.9× what the cheapest tenth charges ($366 vs $2,168).

How the prices are spread

$265 – $336: 31 hospitals$265$336 – $425: 69 hospitals$425 – $539: 103 hospitals$425$539 – $683: 143 hospitals$683 – $865: 135 hospitals$683$865 – $1,096: 163 hospitals$1,096 – $1,388: 145 hospitals$1,096$1,388 – $1,758: 96 hospitals$1,758 – $2,227: 73 hospitals$1,758$2,227 – $2,822: 47 hospitals$2,227median $923price bands are equal on a log scale
Hospitals per price band (1,005 of 1,114 — the bands cover the 5th to 95th percentile)
FromToHospitals
$265$33631
$336$42569
$425$539103
$539$683143
$683$865135
$865$1,096163
$1,096$1,388145
$1,388$1,75896
$1,758$2,22773
$2,227$2,82247

By state

The median cash price in each state, against the national median of $923.

Alaska: 4 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 3 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $545 across 24 hospitalsWA$545Idaho: median $607 across 10 hospitalsID$607Montana: median $1,100 across 14 hospitalsMT$1,100North Dakota: median $493 across 10 hospitalsND$493Minnesota: median $585 across 52 hospitalsMN$585Illinois: median $857 across 46 hospitalsIL$857Wisconsin: median $1,024 across 57 hospitalsWI$1,024Michigan: median $751 across 43 hospitalsMI$751New York: median $893 across 47 hospitalsNY$893Massachusetts: 9 hospitals filed a usable price — fewer than 10, so no figureMAOregon: median $691 across 20 hospitalsOR$691Nevada: 5 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 2 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: median $715 across 12 hospitalsSD$715Iowa: median $592 across 56 hospitalsIA$592Indiana: median $1,135 across 48 hospitalsIN$1,135Ohio: median $1,352 across 39 hospitalsOH$1,352Pennsylvania: median $980 across 38 hospitalsPA$980New Jersey: median $247 across 16 hospitalsNJ$247Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $968 across 75 hospitalsCA$968Utah: median $1,431 across 12 hospitalsUT$1,431Colorado: median $1,008 across 25 hospitalsCO$1,008Nebraska: median $717 across 26 hospitalsNE$717Missouri: median $1,026 across 22 hospitalsMO$1,026Kentucky: median $453 across 10 hospitalsKY$453West Virginia: median $789 across 24 hospitalsWV$789Virginia: median $565 across 17 hospitalsVA$565Maryland: median $1,297 across 16 hospitalsMD$1,297Delaware: 3 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $347 across 10 hospitalsAZ$347New Mexico: median $1,005 across 10 hospitalsNM$1,005Kansas: median $908 across 22 hospitalsKS$908Arkansas: 4 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $546 across 15 hospitalsTN$546North Carolina: median $1,177 across 45 hospitalsNC$1,177South Carolina: median $1,323 across 31 hospitalsSC$1,323Oklahoma: median $700 across 14 hospitalsOK$700Louisiana: median $495 across 17 hospitalsLA$495Mississippi: median $544 across 12 hospitalsMS$544Alabama: 8 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: median $2,177 across 18 hospitalsGA$2,177Hawaii: median $956 across 13 hospitalsHI$956Texas: median $980 across 58 hospitalsTX$980Florida: median $1,282 across 46 hospitalsFL$1,282
Cash price by state, most expensive first. National median $923. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Georgia GA18$2,177+136%$1,078 – $2,767
Utah UT12$1,431+55%$1,193 – $1,602
Ohio OH39$1,352+46%$344 – $1,352
South Carolina SC31$1,323+43%$538 – $2,822
Maryland MD16$1,297+40%$874 – $1,927
Florida FL46$1,282+39%$963 – $1,563
North Carolina NC45$1,177+28%$571 – $2,828
Indiana IN48$1,135+23%$739 – $1,610
Montana MT14$1,100+19%$570 – $1,621
Missouri MO22$1,026+11%$501 – $1,351
Wisconsin WI57$1,024+11%$599 – $1,279
Colorado CO25$1,008+9%$504 – $1,764
New Mexico NM10$1,005+9%$1,005 – $1,005
Texas TX58$980+6%$891 – $2,769
Pennsylvania PA38$980+6%$372 – $1,662
California CA75$968+5%$366 – $1,882
Hawaii HI13$956+4%$655 – $1,253
Kansas KS22$908−2%$638 – $1,196
New York NY47$893−3%$596 – $1,507
Illinois IL46$857−7%$537 – $1,922
West Virginia WV24$789−15%$492 – $1,485
Michigan MI43$751−19%$525 – $1,063
Nebraska NE26$717−22%$437 – $1,104
South Dakota SD12$715−23%$668 – $769
Oklahoma OK14$700−24%$700 – $776
Oregon OR20$691−25%$472 – $2,130
Idaho ID10$607−34%$472 – $1,220
Iowa IA56$592−36%$443 – $997
Minnesota MN52$585−37%$227 – $922
Virginia VA17$565−39%$503 – $702
Tennessee TN15$546−41%$506 – $557
Washington WA24$545−41%$360 – $828
Mississippi MS12$544−41%$276 – $615
Louisiana LA17$495−46%$245 – $611
North Dakota ND10$493−47%$268 – $700
Kentucky KY10$453−51%$152 – $805
Arizona AZ10$347−62%$282 – $778
New Jersey NJ16$247−73%$177 – $896
Massachusetts MA9not enough hospitals filed a usable price
Alabama AL8not enough hospitals filed a usable price
Nevada NV5not enough hospitals filed a usable price
Alaska AK4not enough hospitals filed a usable price
Arkansas AR4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
Delaware DE3not enough hospitals filed a usable price
Maine ME3not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
Wyoming WY2not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $923.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care786$968$501 – $1,563
Children’s39$1,058$614 – $1,864
Critical access287$789$544 – $1,279
Ownership
For-profit94$1,282$611 – $2,425
Government181$858$506 – $1,311
Non-profit837$885$501 – $1,485
System affiliation
Part of a system951$939$515 – $1,497
Independent163$762$476 – $1,559

Cash price vs list price

Median list price (chargemaster)$1,482
Median cash price$923
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

798 hospitals filed a usable inpatient cash price for this code. The median is $936 and the average of the middle 60% is $906; most fall between $504 and $1,462.

Cash price percentiles, inpatient, across 798 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$366$557$936$1,297$2,143

The most expensive tenth of hospitals charges at least 5.9× what the cheapest tenth charges ($366 vs $2,143).

Of the 929 hospitals that filed this code inpatient, 798 gave a usable cash price; 49 carried a plausibility flag, 32 filed a number their own filing marks as not a price, 0 gave an estimate, and 50 a list price only.

How complete is this

1,114 of the 3,956 hospitals with a price file in our corpus (28%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,281 hospitals that filed this code at all gave us
Usable cash price — counted1,114
Cash price carrying a plausibility flag — shown on the compare tool, excluded here72
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded40
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded55
Hospitals that filed this code1,281

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Prophylactic vaccinations and inoculations family.

Hospitals file this code under descriptions such as NIRSEVIMAB-ALIP 100 MG/ML IM SYRG.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “RSV preventive antibody shot for infants, 1 mL dose (CPT 90381) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-90381-rsv-preventive-antibody-shot-for-infants-1-ml-dose