Procedure price report · Other Laboratory

Double-stranded DNA antibody blood test

CPT code CPT 86225the billing code this page is about

Blood test measuring antibodies directed against native double-stranded DNA, used in autoimmune disease evaluation.

Hospitals typically charge $67 cash for this outpatient procedure — the median across 3,291 hospitals that filed a usable cash price; the average of the middle 60% is $70. Most fall between $24 and $132 (20th–80th percentile).

Hospitals
3,291
States
50
Filings dated
Aug 2022 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 3,291 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$15$30$67$118$189

The most expensive tenth of hospitals charges at least 13× what the cheapest tenth charges ($15 vs $189).

How the prices are spread

$10 – $14: 147 hospitals$10$14 – $20: 226 hospitals$20 – $28: 241 hospitals$20$28 – $39: 274 hospitals$39 – $55: 373 hospitals$39$55 – $76: 409 hospitals$76 – $106: 472 hospitals$76$106 – $148: 469 hospitals$148 – $207: 223 hospitals$148$207 – $289: 129 hospitals$207median $67price bands are equal on a log scale
Hospitals per price band (2,963 of 3,291 — the bands cover the 5th to 95th percentile)
FromToHospitals
$10$14147
$14$20226
$20$28241
$28$39274
$39$55373
$55$76409
$76$106472
$106$148469
$148$207223
$207$289129

By state

The median cash price in each state, against the national median of $67.

Alaska: median $93 across 19 hospitalsAK$93Maine: median $52 across 27 hospitalsME$52Vermont: median $103 across 14 hospitalsVT$103New Hampshire: median $86 across 25 hospitalsNH$86Washington: median $68 across 76 hospitalsWA$68Idaho: median $47 across 20 hospitalsID$47Montana: median $51 across 31 hospitalsMT$51North Dakota: median $80 across 33 hospitalsND$80Minnesota: median $80 across 103 hospitalsMN$80Illinois: median $93 across 141 hospitalsIL$93Wisconsin: median $100 across 103 hospitalsWI$100Michigan: median $48 across 100 hospitalsMI$48New York: median $44 across 105 hospitalsNY$44Massachusetts: median $86 across 52 hospitalsMA$86Oregon: median $63 across 50 hospitalsOR$63Nevada: median $67 across 20 hospitalsNV$67Wyoming: median $50 across 16 hospitalsWY$50South Dakota: median $116 across 37 hospitalsSD$116Iowa: median $67 across 86 hospitalsIA$67Indiana: median $42 across 95 hospitalsIN$42Ohio: median $62 across 138 hospitalsOH$62Pennsylvania: median $77 across 120 hospitalsPA$77New Jersey: median $16 across 57 hospitalsNJ$16Connecticut: median $59 across 20 hospitalsCT$59Rhode Island: median $110 across 10 hospitalsRI$110California: median $18 across 145 hospitalsCA$18Utah: median $45 across 42 hospitalsUT$45Colorado: median $77 across 71 hospitalsCO$77Nebraska: median $91 across 75 hospitalsNE$91Missouri: median $69 across 75 hospitalsMO$69Kentucky: median $82 across 67 hospitalsKY$82West Virginia: median $44 across 40 hospitalsWV$44Virginia: median $84 across 73 hospitalsVA$84Maryland: median $85 across 41 hospitalsMD$85Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $90 across 42 hospitalsAZ$90New Mexico: median $101 across 29 hospitalsNM$101Kansas: median $84 across 87 hospitalsKS$84Arkansas: median $27 across 37 hospitalsAR$27Tennessee: median $36 across 81 hospitalsTN$36North Carolina: median $69 across 89 hospitalsNC$69South Carolina: median $113 across 52 hospitalsSC$113Oklahoma: median $65 across 74 hospitalsOK$65Louisiana: median $32 across 50 hospitalsLA$32Mississippi: median $37 across 55 hospitalsMS$37Alabama: median $64 across 43 hospitalsAL$64Georgia: median $78 across 109 hospitalsGA$78Hawaii: median $86 across 21 hospitalsHI$86Texas: median $74 across 243 hospitalsTX$74Florida: median $26 across 145 hospitalsFL$26
Cash price by state, most expensive first. National median $67. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Dakota SD37$116+73%$64 – $192
South Carolina SC52$113+67%$60 – $175
Rhode Island RI10$110+63%$37 – $135
Vermont VT14$103+53%$73 – $212
New Mexico NM29$101+49%$44 – $145
Wisconsin WI103$100+48%$56 – $118
Alaska AK19$93+37%$20 – $139
Illinois IL141$93+37%$44 – $179
Nebraska NE75$91+35%$36 – $132
Arizona AZ42$90+33%$24 – $223
New Hampshire NH25$86+27%$27 – $170
Hawaii HI21$86+27%$69 – $115
Massachusetts MA52$86+27%$34 – $146
Maryland MD41$85+26%$65 – $101
Kansas KS87$84+24%$60 – $122
Virginia VA73$84+24%$45 – $210
Kentucky KY67$82+22%$35 – $272
Minnesota MN103$80+19%$31 – $128
North Dakota ND33$80+19%$25 – $107
Georgia GA109$78+16%$34 – $142
Colorado CO71$77+14%$29 – $131
Pennsylvania PA120$77+14%$22 – $192
Texas TX243$74+10%$16 – $259
North Carolina NC89$69+3%$26 – $135
Missouri MO75$69+2%$34 – $127
Washington WA76$68+1%$27 – $107
Iowa IA86$670%$35 – $111
Nevada NV20$670%$24 – $115
Oklahoma OK74$65−3%$37 – $104
Alabama AL43$64−6%$32 – $181
Oregon OR50$63−7%$42 – $125
Ohio OH138$62−8%$33 – $131
Connecticut CT20$59−13%$35 – $83
Maine ME27$52−23%$29 – $96
Montana MT31$51−24%$19 – $103
Wyoming WY16$50−26%$29 – $96
Michigan MI100$48−29%$16 – $112
Idaho ID20$47−30%$13 – $61
Utah UT42$45−33%$38 – $111
New York NY105$44−35%$20 – $147
West Virginia WV40$44−35%$8 – $76
Indiana IN95$42−38%$30 – $91
Mississippi MS55$37−45%$21 – $77
Tennessee TN81$36−47%$12 – $81
Louisiana LA50$32−52%$22 – $78
Arkansas AR37$27−60%$11 – $121
Florida FL145$26−61%$12 – $101
California CA145$18−74%$6 – $71
New Jersey NJ57$16−77%$15 – $83
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $67.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,270$59$21 – $135
Children’s63$80$27 – $125
Critical access949$77$35 – $125
Ownership
For-profit460$85$25 – $278
Government620$71$27 – $120
Non-profit2,202$63$23 – $128
System affiliation
Part of a system2,672$68$23 – $134
Independent619$66$27 – $113

Cash price vs list price

Median list price (chargemaster)$108
Median cash price$67
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

2,237 hospitals filed a usable inpatient cash price for this code. The median is $66 and the average of the middle 60% is $69; most fall between $24 and $131.

Cash price percentiles, inpatient, across 2,237 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$16$31$66$118$179

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($16 vs $179).

Of the 2,465 hospitals that filed this code inpatient, 2,237 gave a usable cash price; 116 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 112 a list price only.

How complete is this

3,291 of the 3,956 hospitals with a price file in our corpus (83%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,587 hospitals that filed this code at all gave us
Usable cash price — counted3,291
Cash price carrying a plausibility flag — shown on the compare tool, excluded here167
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded128
Hospitals that filed this code3,587

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between July 20, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Hospitals file this code under descriptions such as HC Anti-Dna Native.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Double-stranded DNA antibody blood test (CPT 86225) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-86225-double-stranded-dna-antibody-blood-test